JP2025161809A5 - - Google Patents
Info
- Publication number
- JP2025161809A5 JP2025161809A5 JP2025109210A JP2025109210A JP2025161809A5 JP 2025161809 A5 JP2025161809 A5 JP 2025161809A5 JP 2025109210 A JP2025109210 A JP 2025109210A JP 2025109210 A JP2025109210 A JP 2025109210A JP 2025161809 A5 JP2025161809 A5 JP 2025161809A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- target nucleic
- crispr
- cell
- associated protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962897859P | 2019-09-09 | 2019-09-09 | |
| US62/897,859 | 2019-09-09 | ||
| PCT/US2020/049923 WO2021050534A1 (en) | 2019-09-09 | 2020-09-09 | Novel crispr dna targeting enzymes and systems |
| JP2022515511A JP7705382B2 (ja) | 2019-09-09 | 2020-09-09 | 新規ｃｒｉｓｐｒ ｄｎａターゲティング酵素及びシステム |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022515511A Division JP7705382B2 (ja) | 2019-09-09 | 2020-09-09 | 新規ｃｒｉｓｐｒ ｄｎａターゲティング酵素及びシステム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025161809A JP2025161809A (ja) | 2025-10-24 |
| JP2025161809A5 true JP2025161809A5 (https=) | 2025-11-20 |
Family
ID=74866391
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022515511A Active JP7705382B2 (ja) | 2019-09-09 | 2020-09-09 | 新規ｃｒｉｓｐｒ ｄｎａターゲティング酵素及びシステム |
| JP2025109210A Pending JP2025161809A (ja) | 2019-09-09 | 2025-06-27 | 新規ｃｒｉｓｐｒ ｄｎａターゲティング酵素及びシステム |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022515511A Active JP7705382B2 (ja) | 2019-09-09 | 2020-09-09 | 新規ｃｒｉｓｐｒ ｄｎａターゲティング酵素及びシステム |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US12460190B2 (https=) |
| EP (1) | EP4028047A4 (https=) |
| JP (2) | JP7705382B2 (https=) |
| KR (1) | KR20220054434A (https=) |
| CN (1) | CN114340657A (https=) |
| AU (1) | AU2020347147A1 (https=) |
| CA (1) | CA3150454A1 (https=) |
| IL (1) | IL291095A (https=) |
| MX (1) | MX2022002872A (https=) |
| WO (1) | WO2021050534A1 (https=) |
| ZA (1) | ZA202202628B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3204496A1 (en) | 2014-10-10 | 2017-08-16 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| AU2020347147A1 (en) | 2019-09-09 | 2022-03-03 | Arbor Biotechnologies, Inc. | Novel CRISPR DNA targeting enzymes and systems |
| EP4081533A4 (en) * | 2019-12-23 | 2024-03-20 | The Regents of The University of California | CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHOD OF USE THEREOF |
| WO2022192381A1 (en) | 2021-03-09 | 2022-09-15 | Arbor Biotechnologies, Inc. | Compositions comprising a variant polypeptide and uses thereof |
| US20240174997A1 (en) * | 2021-03-09 | 2024-05-30 | Arbor Biotechnologies, Inc. | Compositions comprising a variant polypeptide and uses thereof |
| IL308806A (en) | 2021-06-01 | 2024-01-01 | Arbor Biotechnologies Inc | Gene editing systems including nuclease crisper and their uses |
| WO2023250384A2 (en) * | 2022-06-22 | 2023-12-28 | The Regents Of The University Of California | Crispr-cas effector polypeptides and methods of use thereof |
| WO2024020557A1 (en) * | 2022-07-22 | 2024-01-25 | Arbor Biotechnologies, Inc. | Compositions comprising a variant nuclease and uses thereof |
| US20240035010A1 (en) * | 2022-07-22 | 2024-02-01 | Arbor Biotechnologies, Inc. | Compositions comprising a variant polypeptide and uses thereof |
| CN117625578B (zh) * | 2022-12-06 | 2024-12-27 | 山东舜丰生物科技有限公司 | Crispr酶和系统及应用 |
| WO2024173645A1 (en) | 2023-02-15 | 2024-08-22 | Arbor Biotechnologies, Inc. | Gene editing method for inhibiting aberrant splicing in stathmin 2 (stmn2) transcript |
| WO2025006563A1 (en) | 2023-06-26 | 2025-01-02 | Arbor Biotechnologies, Inc. | Gene editing systems targeting pcsk9 and uses thereof |
| WO2025171210A1 (en) | 2024-02-09 | 2025-08-14 | Arbor Biotechnologies, Inc. | Compositions and methods for gene editing via homology-mediated end joining |
| WO2025212120A1 (en) | 2024-04-05 | 2025-10-09 | Arbor Biotechnologies, Inc. | Chemical modifications of guide rnas for crispr nucleases |
| WO2026015829A2 (en) | 2024-07-12 | 2026-01-15 | Arbor Biotechnologies, Inc. | Small reverse transcriptases and gene editing systems comprising such |
| WO2026015832A2 (en) | 2024-07-12 | 2026-01-15 | Arbor Biotechnologies, Inc. | Reverse transcriptases and gene editing systems comprising such |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5593972A (en) | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| US20040052799A1 (en) * | 1996-11-15 | 2004-03-18 | Astra Aktiebolag | Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics |
| US20040216190A1 (en) | 2003-04-28 | 2004-10-28 | Kovalic David K. | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| JP4772045B2 (ja) | 2004-07-16 | 2011-09-14 | アメリカ合衆国 | Ｃｍｖ／ｒ核酸コンストラクトを含むａｉｄｓに対するワクチン |
| US8703147B2 (en) | 2007-11-05 | 2014-04-22 | The Walter And Eliza Hall Institute Of Medical Research | Methods and compositions for treating and preventing malaria (2) |
| EP4012714A1 (en) | 2010-03-23 | 2022-06-15 | Iogenetics, LLC. | Bioinformatic processes for determination of peptide binding |
| EP2785370B1 (en) | 2011-12-02 | 2021-07-21 | Rhode Island Hospital | Vaccine for falciparum malaria |
| AU2013359262C1 (en) | 2012-12-12 | 2021-05-13 | Massachusetts Institute Of Technology | CRISPR-Cas component systems, methods and compositions for sequence manipulation |
| WO2016094872A1 (en) | 2014-12-12 | 2016-06-16 | The Broad Institute Inc. | Dead guides for crispr transcription factors |
| WO2016094874A1 (en) | 2014-12-12 | 2016-06-16 | The Broad Institute Inc. | Escorted and functionalized guides for crispr-cas systems |
| US20180187190A1 (en) * | 2015-06-12 | 2018-07-05 | Erasmus University Medical Center Rotterdam | New crispr assays |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| EP4159856A1 (en) | 2015-06-18 | 2023-04-05 | The Broad Institute, Inc. | Novel crispr enzymes and systems |
| CN109153980B (zh) * | 2015-10-22 | 2023-04-14 | 布罗德研究所有限公司 | Vi-b型crispr酶和系统 |
| US20200263190A1 (en) | 2016-04-19 | 2020-08-20 | The Broad Institute, Inc. | Novel crispr enzymes and systems |
| US10125246B2 (en) * | 2016-06-24 | 2018-11-13 | King Fahd University Of Petroleum And Minerals | Low density polyethylene (LDPE)-asphaltene composition and method of preparation |
| WO2018071672A1 (en) * | 2016-10-12 | 2018-04-19 | The Regents Of The University Of Colorado | Novel engineered and chimeric nucleases |
| US11168322B2 (en) * | 2017-06-30 | 2021-11-09 | Arbor Biotechnologies, Inc. | CRISPR RNA targeting enzymes and systems and uses thereof |
| AU2020347147A1 (en) | 2019-09-09 | 2022-03-03 | Arbor Biotechnologies, Inc. | Novel CRISPR DNA targeting enzymes and systems |
-
2020
- 2020-09-09 AU AU2020347147A patent/AU2020347147A1/en active Pending
- 2020-09-09 WO PCT/US2020/049923 patent/WO2021050534A1/en not_active Ceased
- 2020-09-09 MX MX2022002872A patent/MX2022002872A/es unknown
- 2020-09-09 JP JP2022515511A patent/JP7705382B2/ja active Active
- 2020-09-09 EP EP20863249.7A patent/EP4028047A4/en active Pending
- 2020-09-09 CA CA3150454A patent/CA3150454A1/en active Pending
- 2020-09-09 KR KR1020227011364A patent/KR20220054434A/ko active Pending
- 2020-09-09 CN CN202080062919.7A patent/CN114340657A/zh active Pending
- 2020-09-09 US US17/641,523 patent/US12460190B2/en active Active
-
2021
- 2021-10-19 US US17/505,578 patent/US11453867B2/en active Active
-
2022
- 2022-03-03 ZA ZA2022/02628A patent/ZA202202628B/en unknown
- 2022-03-03 IL IL291095A patent/IL291095A/en unknown
- 2022-08-17 US US17/820,444 patent/US11795442B2/en active Active
- 2022-12-28 US US18/147,408 patent/US11976308B2/en active Active
-
2023
- 2023-09-12 US US18/465,755 patent/US20240101990A1/en active Pending
-
2025
- 2025-06-27 JP JP2025109210A patent/JP2025161809A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025161809A5 (https=) | ||
| RU2713328C2 (ru) | Гибридные днк/рнк-полинуклеотиды crispr и способы применения | |
| CN113373130A (zh) | Cas12蛋白、含有Cas12蛋白的基因编辑系统及应用 | |
| CN109136248B (zh) | 多靶点编辑载体及其构建方法和应用 | |
| FI3802807T3 (fi) | Rna-ohjattuja nukleaaseja ja niiden aktiivisia fragmentteja ja variantteja ja menetelmiä niiden käyttämiseksi | |
| AU2020356441B2 (en) | A nucleic acid delivery vector comprising a circular single stranded polynucleotide | |
| WO2018033110A1 (zh) | 一种基因点突变修复的方法 | |
| CN116694603A (zh) | 新型的Cas蛋白、Crispr-Cas系统及其在基因编辑领域中的用途 | |
| WO2023206872A1 (zh) | 一种工程优化的核酸酶、向导rna、编辑系统和应用 | |
| JPWO2021050534A5 (https=) | ||
| WO2023169482A1 (en) | Modified crispr-based gene editing system and methods of use | |
| CN112592923A (zh) | Ires序列、ires序列的应用和多顺反子表达载体 | |
| TW202417017A (zh) | 具有化學修飾的導引rna | |
| JP2022551931A (ja) | 改変エンドヌクレアーゼおよび関連方法 | |
| WO2023165613A1 (zh) | 5'→3'核酸外切酶在基因编辑系统中的用途和基因编辑系统及其编辑方法 | |
| JPWO2021046442A5 (https=) | ||
| US20220364122A1 (en) | Bacterial platform for delivery of gene-editing systems to eukaryotic cells | |
| JPWO2021138247A5 (https=) | ||
| JPWO2021041569A5 (https=) | ||
| JPWO2023275601A5 (https=) | ||
| CN117987464A (zh) | 一种供体构建体、用于修饰细胞基因组的组合物及修饰细胞基因组的方法 | |
| CN116004716A (zh) | 一种复制型dCas9-FokI系统进行高效基因编辑的方法 | |
| JP2024513967A (ja) | 非ウイルス相同性媒介末端結合 | |
| CA3155960C (en) | A nucleic acid delivery vector comprising a circular single stranded polynucleotide | |
| WO2022104381A1 (en) | A MINIMAL CRISPRi/a SYSTEM FOR TARGETED GENOME REGULATION |