MX2022002872A - Nuevas sistemas y enzimas de crispr dirigidos a adn. - Google Patents

Nuevas sistemas y enzimas de crispr dirigidos a adn.

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Publication number
MX2022002872A
MX2022002872A MX2022002872A MX2022002872A MX2022002872A MX 2022002872 A MX2022002872 A MX 2022002872A MX 2022002872 A MX2022002872 A MX 2022002872A MX 2022002872 A MX2022002872 A MX 2022002872A MX 2022002872 A MX2022002872 A MX 2022002872A
Authority
MX
Mexico
Prior art keywords
systems
dna targeting
nucleic acids
novel crispr
crispr dna
Prior art date
Application number
MX2022002872A
Other languages
English (en)
Inventor
David A Scott
David R Cheng
Winston X Yan
Tia M Ditommaso
Original Assignee
Arbor Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arbor Biotechnologies Inc filed Critical Arbor Biotechnologies Inc
Publication of MX2022002872A publication Critical patent/MX2022002872A/es

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C12N9/14—Hydrolases (3)
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/80—Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
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  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
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  • Mycology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La divulgación describe nuevos sistemas, métodos y composiciones para la manipulación de ácidos nucleicos de forma dirigida. La divulgación describe sistemas, componentes y métodos CRISPR diseñados y de origen no natural, para la modificación dirigida de ácidos nucleicos. Cada sistema incluye uno o más componentes proteicos y uno o más componentes de ácido nucleico que se dirigen juntos a los ácidos nucleicos.
MX2022002872A 2019-09-09 2020-09-09 Nuevas sistemas y enzimas de crispr dirigidos a adn. MX2022002872A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962897859P 2019-09-09 2019-09-09
PCT/US2020/049923 WO2021050534A1 (en) 2019-09-09 2020-09-09 Novel crispr dna targeting enzymes and systems

Publications (1)

Publication Number Publication Date
MX2022002872A true MX2022002872A (es) 2022-08-04

Family

ID=74866391

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022002872A MX2022002872A (es) 2019-09-09 2020-09-09 Nuevas sistemas y enzimas de crispr dirigidos a adn.

Country Status (11)

Country Link
US (5) US20220282308A1 (es)
EP (1) EP4028047A4 (es)
JP (1) JP2022547524A (es)
KR (1) KR20220054434A (es)
CN (1) CN114340657A (es)
AU (1) AU2020347147A1 (es)
CA (1) CA3150454A1 (es)
IL (1) IL291095A (es)
MX (1) MX2022002872A (es)
WO (1) WO2021050534A1 (es)
ZA (1) ZA202202628B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4028047A4 (en) 2019-09-09 2023-07-26 Arbor Biotechnologies, Inc. NOVEL ENZYMES AND SYSTEMS TARGETING CRISPR DNA
CA3158403A1 (en) * 2019-12-23 2021-07-01 Jennifer A. Doudna Crispr-cas effector polypeptides and methods of use thereof
CA3210992A1 (en) 2021-03-09 2022-09-15 Shaorong Chong Compositions comprising a variant polypeptide and uses thereof
US20230023791A1 (en) 2021-06-01 2023-01-26 Arbor Biotechnologies, Inc. Gene editing systems comprising a crispr nuclease and uses thereof
WO2023250384A2 (en) * 2022-06-22 2023-12-28 The Regents Of The University Of California Crispr-cas effector polypeptides and methods of use thereof
WO2024020557A1 (en) * 2022-07-22 2024-01-25 Arbor Biotechnologies, Inc. Compositions comprising a variant nuclease and uses thereof
WO2024020567A1 (en) * 2022-07-22 2024-01-25 Arbor Biotechnologies, Inc. Compositions comprising a variant polypeptide and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040052799A1 (en) * 1996-11-15 2004-03-18 Astra Aktiebolag Nucleic acid and amino acid sequences relating to Helicobacter pylori for diagnostics and therapeutics
US20040216190A1 (en) * 2003-04-28 2004-10-28 Kovalic David K. Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement
US8703147B2 (en) * 2007-11-05 2014-04-22 The Walter And Eliza Hall Institute Of Medical Research Methods and compositions for treating and preventing malaria (2)
EP2550529B1 (en) * 2010-03-23 2021-11-17 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
US9662379B2 (en) * 2011-12-02 2017-05-30 Rhode Island Hospital Vaccine for falciparum malaria
EP4159856A1 (en) * 2015-06-18 2023-04-05 The Broad Institute, Inc. Novel crispr enzymes and systems
US20170211142A1 (en) * 2015-10-22 2017-07-27 The Broad Institute, Inc. Novel crispr enzymes and systems
AU2017257274B2 (en) * 2016-04-19 2023-07-13 Massachusetts Institute Of Technology Novel CRISPR enzymes and systems
US10125246B2 (en) * 2016-06-24 2018-11-13 King Fahd University Of Petroleum And Minerals Low density polyethylene (LDPE)-asphaltene composition and method of preparation
WO2018071672A1 (en) * 2016-10-12 2018-04-19 The Regents Of The University Of Colorado Novel engineered and chimeric nucleases
US11168322B2 (en) * 2017-06-30 2021-11-09 Arbor Biotechnologies, Inc. CRISPR RNA targeting enzymes and systems and uses thereof
EP4028047A4 (en) 2019-09-09 2023-07-26 Arbor Biotechnologies, Inc. NOVEL ENZYMES AND SYSTEMS TARGETING CRISPR DNA

Also Published As

Publication number Publication date
US20230212542A1 (en) 2023-07-06
EP4028047A4 (en) 2023-07-26
CN114340657A (zh) 2022-04-12
US11453867B2 (en) 2022-09-27
EP4028047A1 (en) 2022-07-20
ZA202202628B (en) 2023-12-20
WO2021050534A1 (en) 2021-03-18
JP2022547524A (ja) 2022-11-14
US20220282308A1 (en) 2022-09-08
US20230057102A1 (en) 2023-02-23
AU2020347147A1 (en) 2022-03-03
KR20220054434A (ko) 2022-05-02
US20220033793A1 (en) 2022-02-03
US11795442B2 (en) 2023-10-24
IL291095A (en) 2022-05-01
US11976308B2 (en) 2024-05-07
US20240101990A1 (en) 2024-03-28
CA3150454A1 (en) 2021-03-18

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