JP2025109839A5 - - Google Patents

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Publication number
JP2025109839A5
JP2025109839A5 JP2025080039A JP2025080039A JP2025109839A5 JP 2025109839 A5 JP2025109839 A5 JP 2025109839A5 JP 2025080039 A JP2025080039 A JP 2025080039A JP 2025080039 A JP2025080039 A JP 2025080039A JP 2025109839 A5 JP2025109839 A5 JP 2025109839A5
Authority
JP
Japan
Prior art keywords
hla
sla
nucleotide sequences
cells
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025080039A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025109839A (ja
Filing date
Publication date
Priority claimed from JP2022523593A external-priority patent/JP7685249B2/ja
Application filed filed Critical
Publication of JP2025109839A publication Critical patent/JP2025109839A/ja
Publication of JP2025109839A5 publication Critical patent/JP2025109839A5/ja
Pending legal-status Critical Current

Links

JP2025080039A 2019-10-22 2025-05-12 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 Pending JP2025109839A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962924228P 2019-10-22 2019-10-22
US62/924,228 2019-10-22
US201962925859P 2019-10-25 2019-10-25
US62/925,859 2019-10-25
JP2022523593A JP7685249B2 (ja) 2019-10-22 2020-10-22 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法
PCT/US2020/056771 WO2021081156A1 (en) 2019-10-22 2020-10-22 Transgenic swine, methods of making and uses thereof, and methods of making human immune system mice

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022523593A Division JP7685249B2 (ja) 2019-10-22 2020-10-22 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Publications (2)

Publication Number Publication Date
JP2025109839A JP2025109839A (ja) 2025-07-25
JP2025109839A5 true JP2025109839A5 (https=) 2025-11-21

Family

ID=75620265

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022523593A Active JP7685249B2 (ja) 2019-10-22 2020-10-22 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法
JP2025080039A Pending JP2025109839A (ja) 2019-10-22 2025-05-12 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022523593A Active JP7685249B2 (ja) 2019-10-22 2020-10-22 トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法

Country Status (9)

Country Link
US (1) US20220279767A1 (https=)
EP (1) EP4048802A4 (https=)
JP (2) JP7685249B2 (https=)
KR (1) KR20220084296A (https=)
CN (1) CN114585744A (https=)
AU (1) AU2020370254B2 (https=)
CA (1) CA3155234A1 (https=)
IL (1) IL292406A (https=)
WO (1) WO2021081156A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2227584A1 (en) * 1995-08-04 1997-02-20 The General Hospital Corporation Transgenic swine and swine cells having human hla genes
US6639122B1 (en) * 2000-09-19 2003-10-28 Animal Technology Institute Taiwan Transgenic swine having HLA-D gene, swine cells thereof and xenografts therefrom
JP2014503217A (ja) * 2010-12-31 2014-02-13 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク マウスにおける自己t細胞の生成
WO2012145384A1 (en) * 2011-04-20 2012-10-26 University Of Washington Through Its Center For Commercialization Beta-2 microglobulin-deficient cells
DK3590332T3 (da) * 2011-10-28 2022-05-23 Regeneron Pharma Genmodificerede mus, der eksprimerer kimære major histokompatibilitetskompleks (MHC) II-molekyler
EP3058819B1 (en) * 2013-10-18 2021-05-19 Taiho Pharmaceutical Co., Ltd. Hla class i expressing non-human animal
AU2015360502A1 (en) * 2014-12-10 2017-06-29 Regents Of The University Of Minnesota Genetically modified cells, tissues, and organs for treating disease
EP3313176A4 (en) * 2015-06-26 2019-06-26 Indiana University Research&technology Corporation TRANSGENIC PIGS WITH GENETIC MODIFICATIONS OF SLA
MX394999B (es) * 2017-09-29 2025-03-24 Regeneron Pharma Animales no humanos que comprenden un locus ttr humanizado y metodos de uso
KR20210089659A (ko) * 2018-10-05 2021-07-16 제노세라퓨틱스, 인코포레이티드 이종이식 생성물 및 방법

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