JP2023510872A5 - - Google Patents

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Publication number
JP2023510872A5
JP2023510872A5 JP2022542899A JP2022542899A JP2023510872A5 JP 2023510872 A5 JP2023510872 A5 JP 2023510872A5 JP 2022542899 A JP2022542899 A JP 2022542899A JP 2022542899 A JP2022542899 A JP 2022542899A JP 2023510872 A5 JP2023510872 A5 JP 2023510872A5
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JP
Japan
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molecules
manipulated
gene
mhc
cells
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JP2022542899A
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English (en)
Japanese (ja)
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JP2023510872A (ja
JP7853210B2 (ja
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Priority claimed from PCT/US2021/013140 external-priority patent/WO2021146222A1/en
Publication of JP2023510872A publication Critical patent/JP2023510872A/ja
Publication of JP2023510872A5 publication Critical patent/JP2023510872A5/ja
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Publication of JP7853210B2 publication Critical patent/JP7853210B2/ja
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JP2022542899A 2020-01-13 2021-01-12 血液型抗原の修飾 Active JP7853210B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062960607P 2020-01-13 2020-01-13
US202062960617P 2020-01-13 2020-01-13
US62/960,607 2020-01-13
US62/960,617 2020-01-13
PCT/US2021/013140 WO2021146222A1 (en) 2020-01-13 2021-01-12 Modification of blood type antigens

Publications (3)

Publication Number Publication Date
JP2023510872A JP2023510872A (ja) 2023-03-15
JP2023510872A5 true JP2023510872A5 (https=) 2024-01-22
JP7853210B2 JP7853210B2 (ja) 2026-04-28

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JP2022542899A Active JP7853210B2 (ja) 2020-01-13 2021-01-12 血液型抗原の修飾

Country Status (7)

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US (1) US20230272429A1 (https=)
EP (1) EP4090743A1 (https=)
JP (1) JP7853210B2 (https=)
CN (1) CN116234906A (https=)
AU (1) AU2021207810A1 (https=)
CA (1) CA3164591A1 (https=)
WO (1) WO2021146222A1 (https=)

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US11162079B2 (en) 2019-05-10 2021-11-02 The Regents Of The University Of California Blood type O Rh-hypo-immunogenic pluripotent cells
US12221622B2 (en) 2019-05-10 2025-02-11 The Regents Of The University Of California Modified pluripotent cells
BR112023024231A2 (pt) * 2021-05-19 2024-01-30 Sana Biotechnology Inc Células t primárias rhd negativas hipoimunogênicas
US20240358761A1 (en) 2021-08-11 2024-10-31 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy
JP2024535677A (ja) 2021-08-11 2024-10-02 サナ バイオテクノロジー,インコーポレイテッド 即時血液媒介性炎症反応を減少させるための同種細胞療法を目的とした遺伝子改変細胞
EP4384598A1 (en) 2021-08-11 2024-06-19 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions
US20250129346A1 (en) * 2021-08-11 2025-04-24 Sana Biotechnology, Inc. Engineering cells for cell-based therapies, and associated compositions and methods
AU2022325232A1 (en) 2021-08-11 2024-02-08 Sana Biotechnology, Inc. Genetically modified primary cells for allogeneic cell therapy
WO2025117331A1 (en) 2023-12-01 2025-06-05 Eli Lilly And Company Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same
CN118291605A (zh) * 2024-04-10 2024-07-05 深圳市血液中心(深圳市输血医学研究所) 一种基于ngs的多系统红细胞血型基因分型方法和试剂盒
CN118638907A (zh) * 2024-06-26 2024-09-13 中国人民解放军联勤保障部队第九六〇医院 一种用于检测易漏检类孟买表型的snp标记
CN119913243A (zh) * 2025-04-01 2025-05-02 浙江省血液中心 Abo血型变异体的snp位点、b亚型变异型血型鉴定试剂盒和方法

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EP2840140B2 (en) 2012-12-12 2023-02-22 The Broad Institute, Inc. Crispr-Cas based method for mutation of prokaryotic cells
US20140310830A1 (en) 2012-12-12 2014-10-16 Feng Zhang CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes
WO2014093655A2 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
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WO2019084531A1 (en) * 2017-10-27 2019-05-02 The Children's Hospital Of Philadelphia MODIFIED RED GLOBES HAVING PHENOTYPES OF RARE ANTIGENS
WO2020018620A1 (en) * 2018-07-17 2020-01-23 The Regents Of The University Of California Chimeric antigen receptor t cells derived from immunoengineered pluripotent stem cells
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US11162079B2 (en) * 2019-05-10 2021-11-02 The Regents Of The University Of California Blood type O Rh-hypo-immunogenic pluripotent cells
US12221622B2 (en) * 2019-05-10 2025-02-11 The Regents Of The University Of California Modified pluripotent cells

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