JP2022543112A5 - - Google Patents
Info
- Publication number
- JP2022543112A5 JP2022543112A5 JP2022506729A JP2022506729A JP2022543112A5 JP 2022543112 A5 JP2022543112 A5 JP 2022543112A5 JP 2022506729 A JP2022506729 A JP 2022506729A JP 2022506729 A JP2022506729 A JP 2022506729A JP 2022543112 A5 JP2022543112 A5 JP 2022543112A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- gene
- sequence encoding
- group
- dux4
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962881840P | 2019-08-01 | 2019-08-01 | |
| US62/881,840 | 2019-08-01 | ||
| PCT/US2020/044635 WO2021022223A1 (en) | 2019-08-01 | 2020-07-31 | Dux4 expressing cells and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022543112A JP2022543112A (ja) | 2022-10-07 |
| JP2022543112A5 true JP2022543112A5 (https=) | 2023-08-08 |
Family
ID=72088403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506729A Pending JP2022543112A (ja) | 2019-08-01 | 2020-07-31 | Dux4発現細胞およびそれらの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20220267732A1 (https=) |
| EP (1) | EP4007596A1 (https=) |
| JP (1) | JP2022543112A (https=) |
| WO (1) | WO2021022223A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| JP2024501971A (ja) | 2020-12-31 | 2024-01-17 | サナ バイオテクノロジー,インコーポレイテッド | Car-t活性を調節するための方法及び組成物 |
| KR20240011831A (ko) * | 2021-05-26 | 2024-01-26 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법 |
| WO2022269393A1 (en) * | 2021-06-23 | 2022-12-29 | Crispr Therapeutics Ag | Engineered cells with improved protection from natural killer cell killing |
| KR20240046319A (ko) | 2021-07-14 | 2024-04-08 | 사나 바이오테크놀로지, 인크. | 저면역원성 세포에서의 y 염색체-연결 항원의 변경된 발현 |
| AU2022327174A1 (en) | 2021-08-11 | 2024-02-15 | Sana Biotechnology, Inc. | Inducible systems for altering gene expression in hypoimmunogenic cells |
| EP4384598A1 (en) * | 2021-08-11 | 2024-06-19 | Sana Biotechnology, Inc. | Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions |
| US20250339531A1 (en) * | 2021-11-12 | 2025-11-06 | Fred Hutchinson Cancer Center | Dux4 polypeptides and nucleic acids for treating inflammatory and autoimmune conditions |
| CN119072319A (zh) | 2021-12-23 | 2024-12-03 | 萨那生物技术股份有限公司 | 用于治疗自身免疫性疾病的嵌合抗原受体(car)t细胞及相关方法 |
| US20250302953A1 (en) | 2022-02-14 | 2025-10-02 | Sana Biotechnology, Inc. | Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells |
| IL318041A (en) * | 2022-07-01 | 2025-02-01 | Janssen Biotech Inc | Materials and methods for bioengineered iPSC populations |
| WO2024012420A1 (zh) * | 2022-07-11 | 2024-01-18 | 士泽生物医药(苏州)有限公司 | 一种表达faslg的通用型细胞及其制备方法 |
| WO2024125592A1 (zh) * | 2022-12-16 | 2024-06-20 | 士泽生物医药(苏州)有限公司 | 一种通用型细胞及其制备方法 |
| WO2025117331A1 (en) | 2023-12-01 | 2025-06-05 | Eli Lilly And Company | Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same |
| WO2025230941A1 (en) | 2024-04-30 | 2025-11-06 | Satellite Biosciences, Inc. | Hypoimmunogenic cell mixtures and methods of use thereof |
| WO2025230947A1 (en) | 2024-04-30 | 2025-11-06 | Satellite Biosciences, Inc. | Engineered hepatocytes for secreting polypeptides |
| GB202415025D0 (en) * | 2024-10-11 | 2024-11-27 | Ospedale San Raffaele Srl | Cell |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422251A (en) | 1986-11-26 | 1995-06-06 | Princeton University | Triple-stranded nucleic acids |
| GB8724885D0 (en) | 1987-10-23 | 1987-11-25 | Binns M M | Fowlpox virus promotors |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US5420032A (en) | 1991-12-23 | 1995-05-30 | Universitge Laval | Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence |
| US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| DE19539493A1 (de) | 1995-10-24 | 1997-04-30 | Thomae Gmbh Dr K | Starker homologer Promotor aus Hamster |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6599692B1 (en) | 1999-09-14 | 2003-07-29 | Sangamo Bioscience, Inc. | Functional genomics using zinc finger proteins |
| US7070934B2 (en) | 1999-01-12 | 2006-07-04 | Sangamo Biosciences, Inc. | Ligand-controlled regulation of endogenous gene expression |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| US7030215B2 (en) | 1999-03-24 | 2006-04-18 | Sangamo Biosciences, Inc. | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
| AU776576B2 (en) | 1999-12-06 | 2004-09-16 | Sangamo Biosciences, Inc. | Methods of using randomized libraries of zinc finger proteins for the identification of gene function |
| US6689558B2 (en) | 2000-02-08 | 2004-02-10 | Sangamo Biosciences, Inc. | Cells for drug discovery |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| US7067317B2 (en) | 2000-12-07 | 2006-06-27 | Sangamo Biosciences, Inc. | Regulation of angiogenesis with zinc finger proteins |
| JP2005500061A (ja) | 2001-08-20 | 2005-01-06 | ザ スクリップス リサーチ インスティテュート | Cnnについての亜鉛フィンガー結合ドメイン |
| US7262054B2 (en) | 2002-01-22 | 2007-08-28 | Sangamo Biosciences, Inc. | Zinc finger proteins for DNA binding and gene regulation in plants |
| US7361635B2 (en) | 2002-08-29 | 2008-04-22 | Sangamo Biosciences, Inc. | Simultaneous modulation of multiple genes |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7253273B2 (en) | 2004-04-08 | 2007-08-07 | Sangamo Biosciences, Inc. | Treatment of neuropathic pain with zinc finger proteins |
| AU2005232665B2 (en) | 2004-04-08 | 2010-05-13 | Sangamo Therapeutics, Inc. | Methods and compositions for treating neuropathic and neurodegenerative conditions |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
| US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
| CA3111953C (en) | 2011-04-05 | 2023-10-24 | Cellectis | Method for the generation of compact tale-nucleases and uses thereof |
| WO2013130824A1 (en) | 2012-02-29 | 2013-09-06 | Sangamo Biosciences, Inc. | Methods and compositions for treating huntington's disease |
| CN107921148A (zh) | 2015-05-08 | 2018-04-17 | 哈佛学院校长同事会 | 通用供体干细胞和相关方法 |
| WO2018073787A2 (en) * | 2016-10-19 | 2018-04-26 | Fred Hutchinson Cancer Research Center | Compositions and methods for reprogramming cells and for somatic cell nuclear transfer using duxc expression |
| JP2020505025A (ja) | 2017-01-13 | 2020-02-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 免疫工学的な改変をした多能性細胞 |
| CA3094322A1 (en) | 2017-03-20 | 2018-09-27 | Washington University | Cells and methods of uses and making the same |
| WO2020028134A1 (en) * | 2018-07-30 | 2020-02-06 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating cancer |
-
2020
- 2020-07-31 US US17/632,026 patent/US20220267732A1/en active Pending
- 2020-07-31 EP EP20757473.2A patent/EP4007596A1/en active Pending
- 2020-07-31 JP JP2022506729A patent/JP2022543112A/ja active Pending
- 2020-07-31 WO PCT/US2020/044635 patent/WO2021022223A1/en not_active Ceased
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