JP2025060848A5 - - Google Patents
Info
- Publication number
- JP2025060848A5 JP2025060848A5 JP2024229104A JP2024229104A JP2025060848A5 JP 2025060848 A5 JP2025060848 A5 JP 2025060848A5 JP 2024229104 A JP2024229104 A JP 2024229104A JP 2024229104 A JP2024229104 A JP 2024229104A JP 2025060848 A5 JP2025060848 A5 JP 2025060848A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleotides
- acceptor splice
- pyrimidine
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18214415 | 2018-12-20 | ||
| EP18214415.4 | 2018-12-20 | ||
| JP2021534372A JP7668737B2 (ja) | 2018-12-20 | 2019-12-19 | 生物学的および生物工学的用途向けに最適化された受容スプライス部位モジュール |
| PCT/EP2019/086454 WO2020127831A1 (en) | 2018-12-20 | 2019-12-19 | An optimized acceptor splice site module for biological and biotechnological applications |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534372A Division JP7668737B2 (ja) | 2018-12-20 | 2019-12-19 | 生物学的および生物工学的用途向けに最適化された受容スプライス部位モジュール |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025060848A JP2025060848A (ja) | 2025-04-10 |
| JP2025060848A5 true JP2025060848A5 (https=) | 2025-10-09 |
Family
ID=64755152
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534372A Active JP7668737B2 (ja) | 2018-12-20 | 2019-12-19 | 生物学的および生物工学的用途向けに最適化された受容スプライス部位モジュール |
| JP2024229104A Pending JP2025060848A (ja) | 2018-12-20 | 2024-12-25 | 生物学的および生物工学的用途向けに最適化された受容スプライス部位モジュール |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534372A Active JP7668737B2 (ja) | 2018-12-20 | 2019-12-19 | 生物学的および生物工学的用途向けに最適化された受容スプライス部位モジュール |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12502438B2 (https=) |
| EP (1) | EP3898996A1 (https=) |
| JP (2) | JP7668737B2 (https=) |
| KR (1) | KR102938671B1 (https=) |
| CN (1) | CN113474460A (https=) |
| AU (1) | AU2019406702B2 (https=) |
| CA (1) | CA3122909A1 (https=) |
| IL (1) | IL284021A (https=) |
| SG (1) | SG11202106356QA (https=) |
| WO (1) | WO2020127831A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202106356QA (en) * | 2018-12-20 | 2021-07-29 | Vigeneron Gmbh | An optimized acceptor splice site module for biological and biotechnological applications |
| WO2020205604A1 (en) | 2019-03-29 | 2020-10-08 | Salk Institute For Biological Studies | High-efficiency reconstitution of rna molecules |
| US20230287458A1 (en) * | 2020-07-14 | 2023-09-14 | Abeona Therapeutics Inc. | Recombinant adeno-associated viral vectors for multipartite gene delivery |
| US20230374476A1 (en) * | 2021-02-05 | 2023-11-23 | University Of Massachusetts | Prime editor system for in vivo genome editing |
| WO2022220968A1 (en) * | 2021-04-15 | 2022-10-20 | U1 Bio, Inc. | High efficiency trans-splicing for replacement of targeted rna sequences in human cells |
| JP2024517939A (ja) * | 2021-05-14 | 2024-04-23 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 編集タンパク質の発現のための方法および組成物 |
| CN116463380A (zh) * | 2023-03-30 | 2023-07-21 | 中国科学院深圳先进技术研究院 | 一种重组腺相关病毒载体组合物、外源基因表达系统及方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478745A (en) | 1992-12-04 | 1995-12-26 | University Of Pittsburgh | Recombinant viral vector system |
| US20030077754A1 (en) * | 1995-12-15 | 2003-04-24 | Mitchell Lloyd G. | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US20020193580A1 (en) * | 1995-12-15 | 2002-12-19 | Mitchell Lloyd G. | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US6436707B1 (en) * | 1998-03-27 | 2002-08-20 | Lexicon Genetics Incorporated | Vectors for gene mutagenesis and gene discovery |
| JP2009000120A (ja) | 1998-08-13 | 2009-01-08 | Virxsys Corp | スプライソソーム媒介ｒｎａトランス−スプライシングにおける使用のための方法及び組成物 |
| AU780231B2 (en) | 1998-11-10 | 2005-03-10 | University Of North Carolina At Chapel Hill, The | Virus vectors and methods of making and administering the same |
| GB9906615D0 (en) | 1999-03-22 | 1999-05-19 | Oxford Biomedica Ltd | Vector |
| CA2477295A1 (en) | 2002-02-25 | 2003-09-04 | Intronn, Inc. | Trans-splicing mediated imaging of gene expression |
| US7968334B2 (en) | 2004-01-23 | 2011-06-28 | Virxsys Corporation | Expression of apoAI and variants thereof using spliceosome mediated RNA trans-splicing |
| US9303078B2 (en) | 2009-10-08 | 2016-04-05 | Association Institut De Myologie | Nucleic acid molecules and methods for exchanging exon(s) by transsplicing |
| SG2014012207A (en) | 2011-08-12 | 2014-05-29 | Virxsys Corp | Compositions and methods for inducing apoptosis |
| WO2013075008A1 (en) | 2011-11-16 | 2013-05-23 | University Of Florida Research Foundation Inc. | Aav dual vector systems for gene therapy |
| AU2014255665B2 (en) | 2013-04-18 | 2018-08-02 | Fondazione Telethon | Effective delivery of large genes by dual AAV vectors |
| JP7007273B2 (ja) * | 2015-12-22 | 2022-01-24 | アンセルム（アンスティチュート・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル） | 遺伝子治療用の改良された複合型二重組換えａａｖベクターシステム |
| US12043848B2 (en) | 2017-10-16 | 2024-07-23 | Vigeneron Gmbh | AAV vectors |
| SG11202106356QA (en) * | 2018-12-20 | 2021-07-29 | Vigeneron Gmbh | An optimized acceptor splice site module for biological and biotechnological applications |
-
2019
- 2019-12-19 SG SG11202106356QA patent/SG11202106356QA/en unknown
- 2019-12-19 EP EP19829184.1A patent/EP3898996A1/en active Pending
- 2019-12-19 WO PCT/EP2019/086454 patent/WO2020127831A1/en not_active Ceased
- 2019-12-19 US US17/415,643 patent/US12502438B2/en active Active
- 2019-12-19 AU AU2019406702A patent/AU2019406702B2/en active Active
- 2019-12-19 CA CA3122909A patent/CA3122909A1/en active Pending
- 2019-12-19 JP JP2021534372A patent/JP7668737B2/ja active Active
- 2019-12-19 CN CN201980092298.4A patent/CN113474460A/zh active Pending
- 2019-12-19 KR KR1020217018661A patent/KR102938671B1/ko active Active
-
2021
- 2021-06-15 IL IL284021A patent/IL284021A/en unknown
-
2024
- 2024-12-25 JP JP2024229104A patent/JP2025060848A/ja active Pending
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