JP2025032110A5 - - Google Patents
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- Publication number
- JP2025032110A5 JP2025032110A5 JP2024196799A JP2024196799A JP2025032110A5 JP 2025032110 A5 JP2025032110 A5 JP 2025032110A5 JP 2024196799 A JP2024196799 A JP 2024196799A JP 2024196799 A JP2024196799 A JP 2024196799A JP 2025032110 A5 JP2025032110 A5 JP 2025032110A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- seq
- protein
- capsid protein
- aav capsid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025085876A JP2025119015A (ja) | 2019-05-24 | 2025-05-22 | 改変ウイルス粒子およびその使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962852791P | 2019-05-24 | 2019-05-24 | |
| US62/852,791 | 2019-05-24 | ||
| PCT/US2020/034328 WO2020242984A1 (en) | 2019-05-24 | 2020-05-22 | Modified viral particles and uses thereof |
| JP2021569402A JP2022533438A (ja) | 2019-05-24 | 2020-05-22 | 改変ウイルス粒子およびその使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569402A Division JP2022533438A (ja) | 2019-05-24 | 2020-05-22 | 改変ウイルス粒子およびその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025085876A Division JP2025119015A (ja) | 2019-05-24 | 2025-05-22 | 改変ウイルス粒子およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025032110A JP2025032110A (ja) | 2025-03-11 |
| JP2025032110A5 true JP2025032110A5 (https=) | 2025-06-02 |
Family
ID=71094822
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569402A Pending JP2022533438A (ja) | 2019-05-24 | 2020-05-22 | 改変ウイルス粒子およびその使用 |
| JP2024196799A Pending JP2025032110A (ja) | 2019-05-24 | 2024-11-11 | 改変ウイルス粒子およびその使用 |
| JP2025085876A Pending JP2025119015A (ja) | 2019-05-24 | 2025-05-22 | 改変ウイルス粒子およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569402A Pending JP2022533438A (ja) | 2019-05-24 | 2020-05-22 | 改変ウイルス粒子およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025085876A Pending JP2025119015A (ja) | 2019-05-24 | 2025-05-22 | 改変ウイルス粒子およびその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20220241430A1 (https=) |
| EP (1) | EP3976631A1 (https=) |
| JP (3) | JP2022533438A (https=) |
| KR (1) | KR20220011664A (https=) |
| CN (2) | CN113874386A (https=) |
| AR (2) | AR118997A1 (https=) |
| AU (1) | AU2020283537A1 (https=) |
| BR (1) | BR112021023692A2 (https=) |
| CA (1) | CA3140386A1 (https=) |
| CL (2) | CL2021003096A1 (https=) |
| CO (1) | CO2021017692A2 (https=) |
| IL (1) | IL288233A (https=) |
| MA (1) | MA56035A (https=) |
| MX (1) | MX2021014338A (https=) |
| PE (1) | PE20212357A1 (https=) |
| PH (1) | PH12021552887A1 (https=) |
| SG (1) | SG11202112917PA (https=) |
| TW (1) | TW202110869A (https=) |
| WO (1) | WO2020242984A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019227910B2 (en) | 2018-02-28 | 2025-07-17 | The Regents Of The University Of California | A modular system for gene and protein delivery based on AAV |
| JP2022533438A (ja) * | 2019-05-24 | 2022-07-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 改変ウイルス粒子およびその使用 |
| US20240124892A1 (en) * | 2021-03-02 | 2024-04-18 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Adeno-associated viruses and methods and materials for making and using adeno-associated viruses |
| WO2022232575A1 (en) * | 2021-04-30 | 2022-11-03 | Duke University | Compositions comprising adeno-associated virus chimera capsid proteins and methods of using the same |
| CA3222914A1 (en) * | 2021-06-23 | 2022-12-29 | Dyno Therapeutics, Inc. | Capsid variants and methods of using the same |
| US20250302998A1 (en) | 2022-05-09 | 2025-10-02 | Regeneron Pharmaceuticals, Inc. | Vectors and methods for in vivo antibody production |
| EP4536836A1 (en) | 2022-06-07 | 2025-04-16 | Regeneron Pharmaceuticals, Inc. | Pseudotyped viral particles for targeting tcr-expressing cells |
| WO2025042462A2 (en) * | 2023-08-24 | 2025-02-27 | Ohio State Innovation Foundation | Assays and methods for quality control of genome packaging for gene therapy |
| TW202528546A (zh) * | 2023-09-07 | 2025-07-16 | 美商再生元醫藥公司 | 經共價表面修飾之腺相關病毒的生產及純化 |
| TW202540433A (zh) * | 2023-11-21 | 2025-10-16 | 美商再生元醫藥公司 | 藉由活體外接合產生共價表面修飾之腺相關病毒及共價表面修飾的腺相關病毒之純化 |
| WO2026037757A1 (en) | 2024-08-13 | 2026-02-19 | F. Hoffmann-La Roche Ag | Modified aav particles |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2224907A1 (en) * | 1995-07-25 | 1997-02-13 | Introgene B.V. | Methods and means for targeted gene delivery |
| WO1998011244A2 (en) | 1996-09-11 | 1998-03-19 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Aav4 vector and uses thereof |
| US6156303A (en) | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| WO1999061601A2 (en) | 1998-05-28 | 1999-12-02 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Aav5 vector and uses thereof |
| ATE362542T1 (de) | 1998-11-05 | 2007-06-15 | Univ Pennsylvania | Nukleinsäuresequenzen des adeno-assoziierten virus des serotyps i, und vektoren und wirtszellen, die diese enthalten |
| MX359371B (es) * | 2001-11-13 | 2018-09-25 | Univ Pennsylvania | Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo. |
| ES2602610T3 (es) | 2007-05-31 | 2017-02-21 | Medigene Ag | Proteína estructural mutada de un parvovirus |
| ES2724975T3 (es) | 2009-12-10 | 2019-09-18 | Regeneron Pharma | Ratones que producen anticuerpos de cadena pesada |
| GB201002362D0 (en) | 2010-02-11 | 2010-03-31 | Isis Innovation | Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds |
| ES2926774T3 (es) * | 2013-03-15 | 2022-10-28 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores AAV de doble unión de glicano |
| CA2942289C (en) * | 2014-03-10 | 2024-05-21 | Uniqure Ip B.V. | Further improved aav vectors produced in insect cells |
| CA3124228C (en) | 2014-03-21 | 2024-05-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
| EP3151866B1 (en) * | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| US10550405B2 (en) * | 2017-03-15 | 2020-02-04 | The University Of North Carolina At Chapel Hill | Rational polyploid adeno-associated virus vectors and methods of making and using the same |
| PE20200488A1 (es) | 2017-06-27 | 2020-03-03 | Regeneron Pharma | Vectores virales recombinantes con tropismo modificado y usos de estos para la introduccion dirigida de material genetico a celulas humanas |
| LT3645553T (lt) * | 2017-06-27 | 2023-04-25 | Regeneron Pharmaceuticals, Inc. | Modifikuoto tropizmo rekombinantinės viruso dalelės ir jų panaudojimas genetinės medžiagos tiksliniam įvedimui į žmogaus ląsteles |
| AU2019227910B2 (en) * | 2018-02-28 | 2025-07-17 | The Regents Of The University Of California | A modular system for gene and protein delivery based on AAV |
| JP2022533438A (ja) * | 2019-05-24 | 2022-07-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 改変ウイルス粒子およびその使用 |
-
2020
- 2020-05-22 JP JP2021569402A patent/JP2022533438A/ja active Pending
- 2020-05-22 PE PE2021001934A patent/PE20212357A1/es unknown
- 2020-05-22 AU AU2020283537A patent/AU2020283537A1/en active Pending
- 2020-05-22 KR KR1020217041074A patent/KR20220011664A/ko active Pending
- 2020-05-22 TW TW109117155A patent/TW202110869A/zh unknown
- 2020-05-22 SG SG11202112917PA patent/SG11202112917PA/en unknown
- 2020-05-22 CA CA3140386A patent/CA3140386A1/en active Pending
- 2020-05-22 AR ARP200101465A patent/AR118997A1/es unknown
- 2020-05-22 PH PH1/2021/552887A patent/PH12021552887A1/en unknown
- 2020-05-22 MX MX2021014338A patent/MX2021014338A/es unknown
- 2020-05-22 WO PCT/US2020/034328 patent/WO2020242984A1/en not_active Ceased
- 2020-05-22 CN CN202080038612.3A patent/CN113874386A/zh active Pending
- 2020-05-22 EP EP20733099.4A patent/EP3976631A1/en active Pending
- 2020-05-22 US US17/612,669 patent/US20220241430A1/en active Pending
- 2020-05-22 MA MA056035A patent/MA56035A/fr unknown
- 2020-05-22 BR BR112021023692A patent/BR112021023692A2/pt unknown
- 2020-05-22 CN CN202210622571.3A patent/CN114989267A/zh active Pending
-
2021
- 2021-11-18 IL IL288233A patent/IL288233A/en unknown
- 2021-11-19 AR ARP210103220A patent/AR124119A2/es unknown
- 2021-11-23 CL CL2021003096A patent/CL2021003096A1/es unknown
- 2021-12-22 CO CONC2021/0017692A patent/CO2021017692A2/es unknown
-
2023
- 2023-03-03 CL CL2023000629A patent/CL2023000629A1/es unknown
-
2024
- 2024-11-11 JP JP2024196799A patent/JP2025032110A/ja active Pending
-
2025
- 2025-05-22 JP JP2025085876A patent/JP2025119015A/ja active Pending
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