JP2025004176A5 - - Google Patents
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- JP2025004176A5 JP2025004176A5 JP2024176918A JP2024176918A JP2025004176A5 JP 2025004176 A5 JP2025004176 A5 JP 2025004176A5 JP 2024176918 A JP2024176918 A JP 2024176918A JP 2024176918 A JP2024176918 A JP 2024176918A JP 2025004176 A5 JP2025004176 A5 JP 2025004176A5
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710069569.7 | 2017-02-08 | ||
| CN201710069569.7A CN108395482B (zh) | 2017-02-08 | 2017-02-08 | 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定 |
| JP2021119965A JP7241133B2 (ja) | 2017-02-08 | 2021-07-20 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
| JP2023033593A JP7571178B2 (ja) | 2017-02-08 | 2023-03-06 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023033593A Division JP7571178B2 (ja) | 2017-02-08 | 2023-03-06 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025004176A JP2025004176A (ja) | 2025-01-14 |
| JP2025004176A5 true JP2025004176A5 (enExample) | 2025-05-30 |
| JP7767549B2 JP7767549B2 (ja) | 2025-11-11 |
Family
ID=63094096
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563660A Active JP6918145B2 (ja) | 2017-02-08 | 2018-02-08 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
| JP2021119965A Active JP7241133B2 (ja) | 2017-02-08 | 2021-07-20 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
| JP2023033593A Active JP7571178B2 (ja) | 2017-02-08 | 2023-03-06 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
| JP2024176918A Active JP7767549B2 (ja) | 2017-02-08 | 2024-10-09 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563660A Active JP6918145B2 (ja) | 2017-02-08 | 2018-02-08 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
| JP2021119965A Active JP7241133B2 (ja) | 2017-02-08 | 2021-07-20 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
| JP2023033593A Active JP7571178B2 (ja) | 2017-02-08 | 2023-03-06 | Ｃｄ２０抗原を標的とするキメラ抗原受容体の構築およびその遺伝子改変ｔ細胞の活性同定 |
Country Status (16)
| Country | Link |
|---|---|
| US (6) | US11066457B2 (enExample) |
| EP (2) | EP4194473A1 (enExample) |
| JP (4) | JP6918145B2 (enExample) |
| CN (1) | CN108395482B (enExample) |
| DK (1) | DK3599251T5 (enExample) |
| ES (1) | ES2936474T3 (enExample) |
| FI (1) | FI3599251T3 (enExample) |
| HR (1) | HRP20230150T1 (enExample) |
| HU (1) | HUE061346T2 (enExample) |
| LT (1) | LT3599251T (enExample) |
| PL (1) | PL3599251T3 (enExample) |
| PT (1) | PT3599251T (enExample) |
| RS (1) | RS64106B1 (enExample) |
| SI (1) | SI3599251T1 (enExample) |
| SM (1) | SMT202300059T1 (enExample) |
| WO (1) | WO2018145649A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3656977T3 (pl) | 2012-09-14 | 2024-03-04 | Joy Global Underground Mining Llc | Głowica wrębiarki do maszyny górniczej |
| CN108395482B (zh) * | 2017-02-08 | 2021-02-05 | 西比曼生物科技（香港）有限公司 | 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定 |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| US12129304B2 (en) * | 2017-10-19 | 2024-10-29 | F. Hoffmann-La Roche Ag | Treatment of CD20-positive B-cell lymphoma with obinutuzumab |
| CN112955172A (zh) * | 2018-09-17 | 2021-06-11 | 美国卫生和人力服务部 | 靶向cd19和cd20的双顺反子嵌合抗原受体及其用途 |
| JP7386382B2 (ja) | 2018-12-12 | 2023-11-27 | カイト ファーマ インコーポレイテッド | キメラ抗原受容体及びｔ細胞受容体並びに使用方法 |
| CN109593137B (zh) * | 2018-12-29 | 2023-04-14 | 博生吉医药科技(苏州)有限公司 | 抗cd20抗体的新型cd20-car载体的构建及应用 |
| EP3918323A4 (en) | 2019-01-30 | 2022-12-28 | TrueBinding, Inc. | ANTI-GAL3 ANTIBODIES AND USES THEREOF |
| WO2021174124A1 (en) * | 2020-02-27 | 2021-09-02 | Sorrento Therapeutics, Inc. | Dimeric antigen receptors (dar) that bind cd20 |
| CN113402612A (zh) * | 2020-03-17 | 2021-09-17 | 西比曼生物科技（香港）有限公司 | 靶向cd19和cd20的联合嵌合抗原受体及其应用 |
| WO2021242776A2 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
| KR20230122618A (ko) | 2020-12-21 | 2023-08-22 | 알로젠 테라퓨틱스 인코포레이티드 | 프로테아제 활성화 cd45-게이트 car |
| WO2022164886A2 (en) * | 2021-01-27 | 2022-08-04 | Cellular Biomedicine Group Hk Limited | Chimeric antigen receptors targeting cd20 |
| WO2022165233A1 (en) | 2021-01-29 | 2022-08-04 | Allogene Therapeutics, Inc. | KNOCKDOWN OR KNOCKOUT OF ONE OR MORE OF TAP2, NLRC5, β2m, TRAC, RFX5, RFXAP AND RFXANK TO MITIGATE T CELL RECOGNITION OF ALLOGENEIC CELL PRODUCTS |
| IL309957A (en) | 2021-07-14 | 2024-03-01 | 2Seventy Bio Inc | Engineered t cell receptors fused to binding domains from antibodies |
| EP4408442A4 (en) * | 2021-10-01 | 2025-10-29 | Univ Texas | Immune cells loaded with antibodies and their methods of use in cancer treatment |
| WO2023196997A2 (en) | 2022-04-08 | 2023-10-12 | 2Seventy Bio, Inc. | Multipartite receptor and signaling complexes |
| CN117003872A (zh) * | 2022-04-28 | 2023-11-07 | 北京天广实生物技术股份有限公司 | 含有突变轻链可变区骨架的单链抗体片段 |
| EP4562134A1 (en) | 2022-07-29 | 2025-06-04 | Allogene Therapeutics, Inc. | Engineered cells with reduced gene expression to mitigate immune cell recognition |
| EP4626447A1 (en) | 2023-03-31 | 2025-10-08 | AbelZeta Inc. | Bispecific chimeric antigen receptors targeting cd20 and bcma |
| WO2025059162A1 (en) | 2023-09-11 | 2025-03-20 | Dana-Farber Cancer Institute, Inc. | Car-engager containing il-2 variants to enhance the functionality of car t cells |
| WO2025096560A1 (en) | 2023-10-30 | 2025-05-08 | Allogene Therapeutics, Inc. | Engineered cells |
| WO2025097041A1 (en) * | 2023-11-03 | 2025-05-08 | Board Of Regents, The University Of Texas System | Methods for the detection and treatment of resistant cancers co-expressing alpp and/or alpg/alppl2 |
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| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| TWI239352B (en) | 1997-07-23 | 2005-09-11 | Takara Bio Inc | Gene transfer method with the use of serum-free medium |
| US6410319B1 (en) | 1998-10-20 | 2002-06-25 | City Of Hope | CD20-specific redirected T cells and their use in cellular immunotherapy of CD20+ malignancies |
| WO2001029058A1 (en) | 1999-10-15 | 2001-04-26 | University Of Massachusetts | Rna interference pathway genes as tools for targeted genetic interference |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| WO2001096584A2 (en) | 2000-06-12 | 2001-12-20 | Akkadix Corporation | Materials and methods for the control of nematodes |
| US8287864B2 (en) | 2002-02-14 | 2012-10-16 | Immunomedics, Inc. | Structural variants of antibodies for improved therapeutic characteristics |
| PL216630B1 (pl) * | 2002-10-17 | 2014-04-30 | Genmab As | Izolowane ludzkie przeciwciało monoklonalne wiążące ludzki CD20, związane z tym przeciwciałem transfektoma, komórka gospodarza, transgeniczne zwierzę lub roślina, kompozycja, immunokoniugat, cząsteczka bispecyficzna, wektor ekspresyjny, kompozycja farmaceutyczna, zastosowanie medyczne, zestaw oraz przeciwciało antyidiotypowe i jego zastosowanie |
| KR101229731B1 (ko) * | 2003-10-16 | 2013-03-07 | 암젠 리서치 (뮌헨) 게엠베하 | 다중특이적 탈면역화된 ｃｄ3-바인더 |
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| US20130004480A1 (en) * | 2006-07-04 | 2013-01-03 | Paul Parren | CD20 Binding Molecules for the Treatment of Copd |
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| CN106279434B (zh) * | 2014-02-24 | 2020-07-03 | 西比曼生物科技（上海）有限公司 | 工程化cd20靶向性的nkt细胞及其制备方法和应用 |
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| CN109971725B (zh) | 2017-12-28 | 2024-02-02 | 上海细胞治疗研究院 | 抗体修饰的嵌合抗原受体修饰t细胞及其用途 |
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| CN113402612A (zh) | 2020-03-17 | 2021-09-17 | 西比曼生物科技（香港）有限公司 | 靶向cd19和cd20的联合嵌合抗原受体及其应用 |
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2017
- 2017-02-08 CN CN201710069569.7A patent/CN108395482B/zh active Active
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2018
- 2018-02-08 HU HUE18751050A patent/HUE061346T2/hu unknown
- 2018-02-08 JP JP2019563660A patent/JP6918145B2/ja active Active
- 2018-02-08 WO PCT/CN2018/075867 patent/WO2018145649A1/zh not_active Ceased
- 2018-02-08 LT LTEPPCT/CN2018/075867T patent/LT3599251T/lt unknown
- 2018-02-08 US US16/484,482 patent/US11066457B2/en active Active
- 2018-02-08 SM SM20230059T patent/SMT202300059T1/it unknown
- 2018-02-08 ES ES18751050T patent/ES2936474T3/es active Active
- 2018-02-08 HR HRP20230150TT patent/HRP20230150T1/hr unknown
- 2018-02-08 RS RS20230128A patent/RS64106B1/sr unknown
- 2018-02-08 EP EP22206642.5A patent/EP4194473A1/en active Pending
- 2018-02-08 SI SI201830854T patent/SI3599251T1/sl unknown
- 2018-02-08 DK DK18751050.8T patent/DK3599251T5/da active
- 2018-02-08 PL PL18751050.8T patent/PL3599251T3/pl unknown
- 2018-02-08 FI FIEP18751050.8T patent/FI3599251T3/fi active
- 2018-02-08 EP EP18751050.8A patent/EP3599251B1/en active Active
- 2018-02-08 PT PT187510508T patent/PT3599251T/pt unknown
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2021
- 2021-06-21 US US17/352,915 patent/US11472858B2/en active Active
- 2021-07-20 JP JP2021119965A patent/JP7241133B2/ja active Active
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2022
- 2022-04-19 US US17/723,859 patent/US11618778B2/en active Active
- 2022-05-23 US US17/750,855 patent/US11608369B2/en active Active
- 2022-06-03 US US17/831,637 patent/US20220340640A1/en active Pending
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2023
- 2023-02-23 US US18/173,187 patent/US20230242613A1/en active Pending
- 2023-03-06 JP JP2023033593A patent/JP7571178B2/ja active Active
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2024
- 2024-10-09 JP JP2024176918A patent/JP7767549B2/ja active Active