JP2024546875A5 - - Google Patents

Info

Publication number
JP2024546875A5
JP2024546875A5 JP2024535534A JP2024535534A JP2024546875A5 JP 2024546875 A5 JP2024546875 A5 JP 2024546875A5 JP 2024535534 A JP2024535534 A JP 2024535534A JP 2024535534 A JP2024535534 A JP 2024535534A JP 2024546875 A5 JP2024546875 A5 JP 2024546875A5
Authority
JP
Japan
Application number
JP2024535534A
Other languages
Japanese (ja)
Other versions
JPWO2023110918A5 (https=
JP2024546875A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/085689 external-priority patent/WO2023110918A1/en
Publication of JP2024546875A publication Critical patent/JP2024546875A/ja
Publication of JPWO2023110918A5 publication Critical patent/JPWO2023110918A5/ja
Publication of JP2024546875A5 publication Critical patent/JP2024546875A5/ja
Pending legal-status Critical Current

Links

JP2024535534A 2021-12-14 2022-12-13 二連型mhc標的化t細胞エンゲージャー Pending JP2024546875A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163289380P 2021-12-14 2021-12-14
US63/289,380 2021-12-14
US202263317256P 2022-03-07 2022-03-07
US63/317,256 2022-03-07
US202263328417P 2022-04-07 2022-04-07
US63/328,417 2022-04-07
PCT/EP2022/085689 WO2023110918A1 (en) 2021-12-14 2022-12-13 Dual mhc-targeting t cell engager

Publications (3)

Publication Number Publication Date
JP2024546875A JP2024546875A (ja) 2024-12-26
JPWO2023110918A5 JPWO2023110918A5 (https=) 2025-12-23
JP2024546875A5 true JP2024546875A5 (https=) 2025-12-23

Family

ID=84887466

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024535534A Pending JP2024546875A (ja) 2021-12-14 2022-12-13 二連型mhc標的化t細胞エンゲージャー

Country Status (8)

Country Link
US (1) US20250002586A1 (https=)
EP (1) EP4448570A1 (https=)
JP (1) JP2024546875A (https=)
KR (1) KR20240116828A (https=)
AU (1) AU2022413444A1 (https=)
CA (1) CA3240046A1 (https=)
MX (1) MX2024007473A (https=)
WO (1) WO2023110918A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025210181A1 (en) * 2024-04-04 2025-10-09 Cdr-Life Ag Antigen binding proteins targeting an hla-restricted kk-lc-1 peptide

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750325B1 (en) 1989-12-21 2004-06-15 Celltech R&D Limited CD3 specific recombinant antibody
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US7381803B1 (en) 1992-03-27 2008-06-03 Pdl Biopharma, Inc. Humanized antibodies against CD3
GB9524973D0 (en) 1995-12-06 1996-02-07 Lynxvale Ltd Viral vectors
CZ302070B6 (cs) 1998-04-21 2010-09-29 Micromet Ag Jednoretezcový multifunkcní polypeptid, polynukleotid, vektor obsahující tento polynukleotid, bunka transfekovaná tímto polynukleotidem, prostredek obsahující tento polypeptid, polynukleotid nebo vektor a jejich použití a zpusob identifikace aktiváto
AU2003264009A1 (en) 2002-08-15 2004-03-03 Epitomics, Inc. Humanized rabbit antibodies
JP3803790B2 (ja) 2003-02-17 2006-08-02 株式会社東北テクノアーチ 新規なダイアボディ型二重特異性抗体
EP1651659A4 (en) 2003-08-07 2008-09-17 Epitomics Inc METHOD FOR HUMANIZATION OF MONOCLONAL RABBIT ANTIBODIES
DE602004030811D1 (de) 2003-10-16 2011-02-10 Micromet Ag Multispezifische deimmunisierte cd3-bindende moleküle
JP5139800B2 (ja) 2004-06-03 2013-02-06 ノビミューン エスアー 抗cd3抗体およびその使用方法
WO2007101661A1 (en) 2006-03-09 2007-09-13 F.Hoffmann-La Roche Ag Anti-drug antibody assay
US20100015142A1 (en) 2006-12-21 2010-01-21 Macrogenics Inc. Methods for the treatment of lada and other adult- onset autoimmune using immunosuppressive monoclonal antibodies with reduced toxicity
IN2009DN05758A (https=) 2007-03-12 2015-07-24 Esbatech Ag
RS53008B2 (sr) 2007-04-03 2022-12-30 Amgen Res Munich Gmbh Interspecijski specifičan cd3-epsilon vezujući domen
KR20170036814A (ko) 2007-05-21 2017-04-03 앨더바이오 홀딩스 엘엘씨 신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체
KR101530723B1 (ko) 2007-06-25 2015-06-22 에스바테크 - 어 노바티스 컴파니 엘엘씨 단일 쇄 항체의 서열에 기초한 공학처리 및 최적화
US20090074780A1 (en) 2007-06-25 2009-03-19 David Urech Methods of modifying antibodies, and modified antibodies with improved functional properties
CN104004094B (zh) 2008-06-25 2017-09-22 艾斯巴技术-诺华有限责任公司 使用通用抗体构架进行的兔抗体的人源化
PL3241843T3 (pl) 2008-06-25 2021-12-27 Novartis Ag Optymalizacja rozpuszczalności cząsteczek immunowiążących
CA2898100C (en) 2013-01-14 2023-10-10 Xencor, Inc. Novel heterodimeric proteins
CA2902739C (en) 2013-03-15 2022-11-22 Xencor, Inc. Heterodimeric proteins
UA129760C2 (uk) 2013-12-17 2025-07-30 Дженентек, Інк. Анти-cd3 антитіло та спосіб його застосування
CA2939080A1 (en) 2014-02-11 2015-08-20 Genzyme Corporation Assays for detecting the presence or amount of an anti-drug antibody
CN110894240B (zh) 2014-11-26 2022-04-15 森科股份有限公司 结合cd3和肿瘤抗原的异二聚体抗体
EP3602056A1 (en) 2017-03-31 2020-02-05 Ablynx N.V. Improved immunogenicity assays
SG11202000025SA (en) * 2017-07-14 2020-02-27 Immatics Biotechnologies Gmbh Improved dual specificity polypeptide molecule
RU2020135920A (ru) 2018-04-05 2022-05-05 Новартис Аг Триспецифические связывающие молекулы против форм рака и пути их применения
CN118852456A (zh) * 2019-05-29 2024-10-29 Cue生物制药股份有限公司 多聚体t细胞调节多肽及其使用方法
EP4025908A4 (en) 2019-09-05 2023-07-19 Adverum Biotechnologies, Inc. ANTI-DRUG ANTIBODY TEST
NL2024375B1 (en) * 2019-12-04 2021-08-31 Apo T B V Methods and means for attracting immune effector cells to tumor cells.
KR20220113492A (ko) * 2019-12-11 2022-08-12 몰리큘라 파트너스 아게 변경된 표면 잔기를 갖는 설계된 안키린 반복 도메인
EP4304725A1 (en) 2021-03-09 2024-01-17 CDR-Life AG Rabbit-derived antigen binding protein nucleic acid libraries
US11912771B2 (en) 2021-03-09 2024-02-27 Cdr-Life Ag MAGE-A4 peptide-MHC antigen binding proteins

Similar Documents

Publication Publication Date Title
BR102022025291A2 (https=)
BR102023014872A2 (https=)
BR102023012440A2 (https=)
BR102023010976A2 (https=)
BR102023009641A2 (https=)
BR102023008688A2 (https=)
BR102023007252A2 (https=)
BR102023005164A2 (https=)
BR102023001877A2 (https=)
BR102023000289A2 (https=)
BR102022026909A2 (https=)
BR102022023461A2 (https=)
BR202022009269U2 (https=)
BR202022005961U2 (https=)
BR202022001779U2 (https=)
BR202022000931U2 (https=)
BY13149U (https=)
BY13159U (https=)
BY13140U (https=)
BY13141U (https=)
BY13142U (https=)
BY13143U (https=)
BY13176U (https=)
BY13145U (https=)
BY13174U (https=)