|
US4039676A
(en)
|
1975-06-23 |
1977-08-02 |
Ciba-Geigy Corporation |
2-piperidinoalkyl-1,4-benzodioxans
|
|
US6518423B1
(en)
|
1996-08-09 |
2003-02-11 |
Eisai Co., Ltd. |
Benzopiperidine derivatives
|
|
FR2793246B1
(fr)
|
1999-05-03 |
2001-06-29 |
Adir |
Nouveaux derives de 1-aza-2-alkyl-6-aryl-cycloalcanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
AU7514700A
(en)
|
1999-09-07 |
2001-04-10 |
Syngenta Participations Ag |
Cyanopiperidines
|
|
FR2801585B1
(fr)
|
1999-11-25 |
2002-02-15 |
Fournier Ind & Sante |
Nouveaux antagonistes des recepteurs de l'ii-8
|
|
AU2002211828A1
(en)
|
2000-10-02 |
2002-04-15 |
Merck & Co., Inc. |
Inhibitors of prenyl-protein transferase
|
|
FR2824827B1
(fr)
|
2001-05-17 |
2004-02-13 |
Fournier Lab Sa |
Nouveaux derives de 5-phenyl-1h-indole antagoniste des recepteurs de l'interleukine-8
|
|
FR2824826B1
(fr)
|
2001-05-17 |
2003-11-07 |
Fournier Lab Sa |
Nouveaux derives de 5-cyano-1h-indole antagonistes des recepteurs de l'interleukine-8
|
|
WO2003104180A1
(en)
|
2002-06-05 |
2003-12-18 |
Natco Pharma Limited |
Process for the preparation of 4-(4-fluorobenzoyl) butyric acid
|
|
JP2007504221A
(ja)
|
2003-09-03 |
2007-03-01 |
ガラパゴス・エヌブイ |
新規な4−ピペリジンカルボキシアミドおよび5ht2a受容体関連障害に対する薬剤の製造のためのその使用
|
|
BRPI0507657A
(pt)
|
2004-03-03 |
2007-07-10 |
Lilly Co Eli |
composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, método para tratar um distúrbio, e, uso de um composto ou um sal farmaceuticamente aceitável do mesmo
|
|
AR048523A1
(es)
|
2004-04-07 |
2006-05-03 |
Kalypsys Inc |
Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos
|
|
JP5406722B2
(ja)
|
2006-10-16 |
2014-02-05 |
グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング |
ブラジキニン1受容体モジュレータとしての置換されたスルホンアミド誘導体
|
|
PT2118074E
(pt)
|
2007-02-01 |
2014-03-20 |
Resverlogix Corp |
Compostos para a prevenção e tratamento de doenças cardiovasculares
|
|
DK2178870T3
(en)
|
2007-08-17 |
2018-10-22 |
Lg Chemical Ltd |
INDOLE AND INDAZOLIC COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSE
|
|
CN105254557A
(zh)
|
2009-05-29 |
2016-01-20 |
拉夸里亚创药株式会社 |
作为钙或钠通道阻滞剂的芳基取代羧酰胺衍生物
|
|
WO2012025155A1
(en)
|
2010-08-26 |
2012-03-01 |
Novartis Ag |
Hydroxamate-based inhibitors of deacetylases
|
|
BR102012024778A2
(pt)
|
2012-09-28 |
2014-08-19 |
Cristalia Prod Quimicos Farm |
Compostos heteroaromáticos; processo para preparar os compostos, composições farmacêuticas, usos e método de tratamento para as dores aguda e crônica
|
|
US10130632B2
(en)
|
2012-11-27 |
2018-11-20 |
Beth Israel Deaconess Medical Center, Inc. |
Methods for treating renal disease
|
|
EP3049405A4
(en)
|
2013-09-26 |
2017-03-08 |
Pharmakea Inc. |
Autotaxin inhibitor compounds
|
|
EP3186225A4
(en)
|
2014-08-27 |
2018-02-28 |
The Governing Council of the University of Toronto |
Cannabinoid type 1 receptor modulators
|
|
US10654838B2
(en)
|
2014-10-08 |
2020-05-19 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Aminopyridine compounds useful as inhibitors of protein prenylation
|
|
HUE053705T2
(hu)
|
2015-08-27 |
2021-07-28 |
Pfizer |
Biciklusos kondenzált heteroaril- vagy aril- vegyületek IRAK4 modulátorokként
|
|
CN106749330A
(zh)
|
2016-12-29 |
2017-05-31 |
长春海谱润斯科技有限公司 |
一种杂环衍生物及使用该杂环衍生物的有机发光器件
|
|
EP3787669A4
(en)
|
2018-04-30 |
2022-03-30 |
The Trustees of Indiana University |
COMPOUNDS FOR MODULATION OF LEVELS OF DDAH AND ADMA AND METHODS OF USE THEM TO TREAT DISEASES
|
|
US11618746B2
(en)
|
2018-12-17 |
2023-04-04 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of APOL1 and methods of using same
|
|
US20220144838A1
(en)
|
2019-03-13 |
2022-05-12 |
Nanjing Immunophage Biotech Co., Ltd. |
Compounds as Inhibitors of Macrophage Migration Inhibitory Factor
|
|
WO2021154997A1
(en)
|
2020-01-29 |
2021-08-05 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of apol1 and methods of using same
|
|
US20210246121A1
(en)
|
2020-02-04 |
2021-08-12 |
Vertex Pharmaceuticals Incorporated |
Solid forms of apol1 inhibitor and methods of using same
|
|
IL296035A
(en)
|
2020-03-06 |
2022-10-01 |
Vertex Pharma |
Methods of treating apol-1 dependent focal segmental glomerulosclerosis
|
|
IL296423A
(en)
|
2020-04-22 |
2022-11-01 |
Anima Biotech Inc |
Collagen 1 translation inhibitors and methods of use thereof
|
|
JP2023524563A
(ja)
|
2020-05-07 |
2023-06-12 |
ラムバム メド-テック リミテッド |
Apol1-関連疾患の治療に使用するための組成物
|
|
CN115867532A
(zh)
|
2020-06-12 |
2023-03-28 |
弗特克斯药品有限公司 |
Apol1的抑制剂及其用途
|
|
CA3185604A1
(en)
|
2020-06-12 |
2021-12-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of apol1 and use of the same
|
|
CN115867543A
(zh)
|
2020-06-12 |
2023-03-28 |
弗特克斯药品有限公司 |
Apol1抑制剂的固体形式及其使用方法
|
|
CN116547287B
(zh)
|
2020-08-26 |
2025-09-26 |
弗特克斯药品有限公司 |
Apol1的抑制剂及其使用方法
|
|
US20230119114A1
(en)
|
2021-08-26 |
2023-04-20 |
Vertex Pharmaceuticals Incorporated |
Solid forms of apol1 inhibitors and methods of using same
|
|
EP4440697A1
(en)
|
2021-11-30 |
2024-10-09 |
Vertex Pharmaceuticals Incorporated |
Spirocyclic inhibitors of apol1 and methods of using same
|
|
CN119212986A
(zh)
|
2022-02-08 |
2024-12-27 |
弗特克斯药品有限公司 |
作为apol1的抑制剂的螺哌啶衍生物及其使用方法
|
|
AU2023219516A1
(en)
|
2022-02-08 |
2024-08-22 |
Vertex Pharmaceuticals Incorporated |
2-methyl-4-phenylpiperidin-4-ol derivatives as inhibitors of apol1 and methods of using same
|
|
EP4476228A1
(en)
|
2022-02-08 |
2024-12-18 |
Vertex Pharmaceuticals Incorporated |
4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] derivatives as inhibitors of apol1 and methods of using same
|
|
CA3251050A1
(en)
|
2022-02-08 |
2023-08-17 |
Vertex Pharmaceuticals Incorporated |
2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES USED AS APOL1 INHIBITORS AND THEIR METHODS OF USE
|