JP2024542001A5 - - Google Patents

Info

Publication number
JP2024542001A5
JP2024542001A5 JP2024525459A JP2024525459A JP2024542001A5 JP 2024542001 A5 JP2024542001 A5 JP 2024542001A5 JP 2024525459 A JP2024525459 A JP 2024525459A JP 2024525459 A JP2024525459 A JP 2024525459A JP 2024542001 A5 JP2024542001 A5 JP 2024542001A5
Authority
JP
Japan
Prior art keywords
alkyl
optionally substituted
independently selected
nr8r9
glycero
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525459A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024542001A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/048223 external-priority patent/WO2023076598A1/en
Publication of JP2024542001A publication Critical patent/JP2024542001A/ja
Publication of JP2024542001A5 publication Critical patent/JP2024542001A5/ja
Pending legal-status Critical Current

Links

JP2024525459A 2021-10-29 2022-10-28 脂質アミン Pending JP2024542001A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163273421P 2021-10-29 2021-10-29
US63/273,421 2021-10-29
US202263308180P 2022-02-09 2022-02-09
US63/308,180 2022-02-09
US202263395243P 2022-08-04 2022-08-04
US63/395,243 2022-08-04
PCT/US2022/048223 WO2023076598A1 (en) 2021-10-29 2022-10-28 Lipid amines

Publications (2)

Publication Number Publication Date
JP2024542001A JP2024542001A (ja) 2024-11-13
JP2024542001A5 true JP2024542001A5 (enExample) 2025-11-17

Family

ID=84365358

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525459A Pending JP2024542001A (ja) 2021-10-29 2022-10-28 脂質アミン

Country Status (5)

Country Link
US (1) US20260109732A1 (enExample)
EP (1) EP4423107A1 (enExample)
JP (1) JP2024542001A (enExample)
TW (1) TW202332467A (enExample)
WO (1) WO2023076598A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118324841A (zh) * 2023-01-10 2024-07-12 辽宁键凯科技有限公司 一种类固醇-阳离子脂质化合物及其应用
CN121487722A (zh) * 2023-04-14 2026-02-06 北京剂泰生命科技有限公司 靶向脾的脂质纳米颗粒
AU2024265267A1 (en) * 2023-05-03 2025-11-20 Modernatx, Inc. Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
WO2024249920A2 (en) * 2023-05-31 2024-12-05 Northwestern University Lipid-gold salt molecules and formulation in lipid nanoparticle delivery systems

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US6071890A (en) * 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
DE19631189A1 (de) * 1996-08-02 1998-02-05 Max Delbrueck Centrum Neuartige kationische Amphiphile für den liposomalen Gentransfer
US5942634A (en) * 1997-05-09 1999-08-24 Genzyme Corporation Cationic amphiphiles for cell transfections
US6169078B1 (en) * 1998-05-12 2001-01-02 University Of Florida Materials and methods for the intracellular delivery of substances
US6656498B1 (en) * 1998-11-25 2003-12-02 Vanderbilt University Cationic liposomes for gene transfer
FR2797188A1 (fr) * 1999-08-04 2001-02-09 Univ Paris Nord Laboratoire De Composes lipidiques cationiques et leurs utilisation pour le transfert de substances d'interet therapeutique chargees negativement
JP5902197B2 (ja) 2011-01-11 2016-04-13 アルニラム・ファーマシューティカルズ・インコーポレーテッド Peg化脂質および薬剤送達のためのそれらの使用
WO2014172045A1 (en) 2013-03-15 2014-10-23 The University Of British Columbia Lipid nanoparticles for transfection and related methods
WO2015198326A1 (en) * 2014-06-26 2015-12-30 Ramot At Tel-Aviv University Ltd. Liposomal formulations for delivery of nucleic acids
EP4710943A3 (en) * 2015-08-28 2026-04-29 Molecular Transfer, Inc. Transfection complexes and methods of using the same
JP2023538260A (ja) * 2020-08-06 2023-09-07 モダーナティエックス・インコーポレイテッド ペイロード分子を気道上皮に送達するための組成物
WO2022104131A1 (en) * 2020-11-13 2022-05-19 Modernatx, Inc. Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis

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