JP2024542001A5 - - Google Patents
Info
- Publication number
- JP2024542001A5 JP2024542001A5 JP2024525459A JP2024525459A JP2024542001A5 JP 2024542001 A5 JP2024542001 A5 JP 2024542001A5 JP 2024525459 A JP2024525459 A JP 2024525459A JP 2024525459 A JP2024525459 A JP 2024525459A JP 2024542001 A5 JP2024542001 A5 JP 2024542001A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- independently selected
- nr8r9
- glycero
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163273421P | 2021-10-29 | 2021-10-29 | |
| US63/273,421 | 2021-10-29 | ||
| US202263308180P | 2022-02-09 | 2022-02-09 | |
| US63/308,180 | 2022-02-09 | ||
| US202263395243P | 2022-08-04 | 2022-08-04 | |
| US63/395,243 | 2022-08-04 | ||
| PCT/US2022/048223 WO2023076598A1 (en) | 2021-10-29 | 2022-10-28 | Lipid amines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024542001A JP2024542001A (ja) | 2024-11-13 |
| JP2024542001A5 true JP2024542001A5 (enExample) | 2025-11-17 |
Family
ID=84365358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024525459A Pending JP2024542001A (ja) | 2021-10-29 | 2022-10-28 | 脂質アミン |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20260109732A1 (enExample) |
| EP (1) | EP4423107A1 (enExample) |
| JP (1) | JP2024542001A (enExample) |
| TW (1) | TW202332467A (enExample) |
| WO (1) | WO2023076598A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4628497A4 (en) * | 2023-01-10 | 2026-05-13 | Jenkem Tech Co Ltd Liaoning | CATIONIC STEROID-LIPID COMPOUND AND ITS USES |
| EP4694871A1 (en) * | 2023-04-14 | 2026-02-18 | Beijing Jitai Pharmaceutical Technology Co., Ltd. | Lipid nanoparticle compositions and uses thereof |
| EP4704816A1 (en) * | 2023-05-03 | 2026-03-11 | ModernaTX, Inc. | Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis |
| WO2024249920A2 (en) * | 2023-05-31 | 2024-12-05 | Northwestern University | Lipid-gold salt molecules and formulation in lipid nanoparticle delivery systems |
| CN118027129A (zh) * | 2024-01-04 | 2024-05-14 | 江苏申基生物科技有限公司 | 一种可电离脂质化合物及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681702A (en) | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| US6071890A (en) * | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| DE19631189A1 (de) * | 1996-08-02 | 1998-02-05 | Max Delbrueck Centrum | Neuartige kationische Amphiphile für den liposomalen Gentransfer |
| US5942634A (en) * | 1997-05-09 | 1999-08-24 | Genzyme Corporation | Cationic amphiphiles for cell transfections |
| US6169078B1 (en) * | 1998-05-12 | 2001-01-02 | University Of Florida | Materials and methods for the intracellular delivery of substances |
| WO2000030444A1 (en) * | 1998-11-25 | 2000-06-02 | Vanderbilt University | Cationic liposomes for gene transfer |
| FR2797188A1 (fr) * | 1999-08-04 | 2001-02-09 | Univ Paris Nord Laboratoire De | Composes lipidiques cationiques et leurs utilisation pour le transfert de substances d'interet therapeutique chargees negativement |
| EP2217221B1 (en) * | 2007-10-17 | 2018-06-27 | Korea Advanced Institute of Science and Technology | Ldl-like cationic nanoparticles for deliverying nucleic acid gene, method for preparing thereof and method for deliverying nucleic acid gene using the same |
| US9999673B2 (en) | 2011-01-11 | 2018-06-19 | Alnylam Pharmaceuticals, Inc. | PEGylated lipids and their use for drug delivery |
| KR20140048404A (ko) * | 2012-10-11 | 2014-04-24 | 포항공과대학교 산학협력단 | 저밀도 지단백질 유사 나노입자 및 이를 포함하는 간 표적 진단 및 치료용 조성물 |
| CN105143456A (zh) | 2013-03-15 | 2015-12-09 | 不列颠哥伦比亚大学 | 用于转染的脂质纳米粒子和相关方法 |
| JP2017520549A (ja) * | 2014-06-26 | 2017-07-27 | ラモット アット テル アビブ ユニバーシティ， リミテッド | 核酸の送達のためのリポソーム製剤 |
| EP4710943A3 (en) * | 2015-08-28 | 2026-04-29 | Molecular Transfer, Inc. | Transfection complexes and methods of using the same |
| JP7332478B2 (ja) * | 2017-03-15 | 2023-08-23 | モデルナティエックス インコーポレイテッド | 脂質ナノ粒子製剤 |
| US11529314B2 (en) * | 2017-11-10 | 2022-12-20 | Board Of Regents, The University Of Texas System | Lipid-based nanoparticles for encapsulation and sustained release of therapeutic agents |
| WO2022032154A2 (en) * | 2020-08-06 | 2022-02-10 | Modernatx, Inc. | Compositions for the delivery of payload molecules to airway epithelium |
| CA3199784A1 (en) * | 2020-11-13 | 2022-05-19 | Modernatx, Inc. | Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis |
-
2022
- 2022-10-28 US US18/705,135 patent/US20260109732A1/en active Pending
- 2022-10-28 JP JP2024525459A patent/JP2024542001A/ja active Pending
- 2022-10-28 EP EP22814249.3A patent/EP4423107A1/en active Pending
- 2022-10-28 TW TW111141006A patent/TW202332467A/zh unknown
- 2022-10-28 WO PCT/US2022/048223 patent/WO2023076598A1/en not_active Ceased
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