JP2024540002A5 - - Google Patents

Info

Publication number
JP2024540002A5
JP2024540002A5 JP2024525021A JP2024525021A JP2024540002A5 JP 2024540002 A5 JP2024540002 A5 JP 2024540002A5 JP 2024525021 A JP2024525021 A JP 2024525021A JP 2024525021 A JP2024525021 A JP 2024525021A JP 2024540002 A5 JP2024540002 A5 JP 2024540002A5
Authority
JP
Japan
Prior art keywords
retroviral vector
leukemia virus
mouse leukemia
recombinant retroviral
vector according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525021A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540002A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/047596 external-priority patent/WO2023076177A2/en
Publication of JP2024540002A publication Critical patent/JP2024540002A/ja
Publication of JP2024540002A5 publication Critical patent/JP2024540002A5/ja
Pending legal-status Critical Current

Links

JP2024525021A 2021-10-25 2022-10-24 治療剤送達のための組成物および方法 Pending JP2024540002A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163271674P 2021-10-25 2021-10-25
US63/271,674 2021-10-25
US202263413165P 2022-10-04 2022-10-04
US63/413,165 2022-10-04
PCT/US2022/047596 WO2023076177A2 (en) 2021-10-25 2022-10-24 Compositions and methods for therapeutic delivery

Publications (2)

Publication Number Publication Date
JP2024540002A JP2024540002A (ja) 2024-10-31
JP2024540002A5 true JP2024540002A5 (https=) 2025-11-04

Family

ID=86158435

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525021A Pending JP2024540002A (ja) 2021-10-25 2022-10-24 治療剤送達のための組成物および方法

Country Status (8)

Country Link
US (2) US12234475B2 (https=)
EP (1) EP4423287A4 (https=)
JP (1) JP2024540002A (https=)
KR (1) KR20240099339A (https=)
AU (1) AU2022375623A1 (https=)
CA (1) CA3235894A1 (https=)
TW (1) TW202325851A (https=)
WO (1) WO2023076177A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3235894A1 (en) 2021-10-25 2023-05-04 Brile Chung Compositions and methods for therapeutic delivery

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19651443A1 (de) 1996-12-11 1998-06-18 Hoechst Ag Selbstverstärkende, pharmakologisch kontrollierbare Expressionssysteme
WO1998044938A1 (en) 1997-04-10 1998-10-15 University Of Southern California Modified proteins which bind extracellular matrix components
EP1914304A1 (en) 1998-10-14 2008-04-23 Darwin Molecular Corporation Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
JP2002516061A (ja) * 1997-10-14 2002-06-04 ダーウィン モレキュラー コーポレイション チミジンキナーゼ変異体ならびにチミジンキナーゼ活性およびグアニル酸キナーゼ活性を有する融合タンパク質
US6743631B1 (en) 1998-03-17 2004-06-01 North Shore University Hospital Research Corporation Use of human serum resistant vector particles and cell lines for human gene therapy
GB9810999D0 (en) * 1998-05-21 1998-07-22 Goken Joop Materials and methods relating to the expression of genes
US6490476B1 (en) 1999-10-14 2002-12-03 Cti Pet Systems, Inc. Combined PET and X-ray CT tomograph and method for using same
US6825033B2 (en) 2000-03-02 2004-11-30 University Of Southern California Mutated cyclin G1 protein
US20010046491A1 (en) 2000-03-23 2001-11-29 Valerie Kristoffer C. Tumor radiosensitization with mutant thymidine kinase in combination with a prodrug
US20050130132A1 (en) 2002-09-06 2005-06-16 Day Craig H. Compositions and methods for the diagnosis and treatment of herpes simplex virus infection
US20060216299A1 (en) 2002-10-30 2006-09-28 Rigel Pharmaceuticals, Inc. Cell cycle targets and peptides
US20070178066A1 (en) 2003-04-21 2007-08-02 Hall Frederick L Pathotropic targeted gene delivery system for cancer and other disorders
US20090123428A1 (en) 2003-04-21 2009-05-14 Hall Frederick L Pathotropic targeted gene delivery system for cancer and other disorders
US7815902B2 (en) 2003-07-09 2010-10-19 Henry Ford Health System Methods and compositions for cancer therapy using a novel adenovirus
WO2005007109A2 (en) 2003-07-09 2005-01-27 Henry Ford Health System Methods and compositions for cancer therapy using a novel adenovirus
US7632509B2 (en) * 2005-07-19 2009-12-15 Biosante Pharmaceuticals, Inc. Methods to express recombinant proteins from lentiviral vectors
CA2643102A1 (en) 2006-03-21 2007-09-27 The Regents Of The University Of California A method for noninvasively and quantitatively monitoring therapeutic and diagnostic transgene expression induced by ex vivo and in vivo gene targeting in organs, tissues and cells
PT2145189E (pt) 2007-05-08 2016-06-16 Us Health Pseudovírus de papilomavírus para deteção e terapêutica de tumores
CA2690627C (en) 2007-06-15 2014-12-02 Genelux Corporation Microorganisms for imaging and/or treatment of tumors
WO2009070636A2 (en) 2007-11-27 2009-06-04 Stanford University Engineered cells, imaging reporter gene/probe systems, and methods of imaging
US20090176260A1 (en) 2007-12-04 2009-07-09 Joseph Ching-Ming Wu Double-fusion human embryonic stem cells, methods of making double-fusion human embryonic stem cells, triple-fusion human embryonic stem cells, methods of making triple-fusion human embryonic stem cells, and methods of monitoring double-fusion human embryonic stem cells and triple-fusion human embryonic stem cells
US9296790B2 (en) 2008-10-03 2016-03-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for protein delivery
EP2376518A4 (en) 2008-12-18 2013-12-04 Avaris Ab COMPLEX AND METHOD FOR AMPLIFYING NUCLEAR RELEASE
KR101032871B1 (ko) 2009-07-10 2011-05-06 주식회사 바이오드 비엠피-2와 에이치에스브이-티케이 자살유전자를 동시에 포함하고 발현 할 수 있도록 하는 벡터와 이 벡터가 도입된 자가조절형 줄기세포 치료제
KR20140027063A (ko) 2010-10-28 2014-03-06 버지니아 커먼웰스 유니버시티 치료와 병용하는 암 영상화: 치료진단
JP2015505326A (ja) 2012-01-18 2015-02-19 ニューメディシンズ,インコーポレーテッド 放射線防護及び放射線誘発性毒性緩和のためのil−12
AU2014236208B2 (en) 2013-03-14 2018-07-19 Genvivo, Inc. Thymidine kinase diagnostic assay for gene therapy applications
JP2018526007A (ja) * 2015-09-04 2018-09-13 トカジェン インコーポレーテッド 2aペプチドを含む組換えベクター
WO2017147269A1 (en) * 2016-02-23 2017-08-31 Salk Institute For Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
EP3568474A1 (en) * 2017-01-10 2019-11-20 Intrexon Corporation Modulating expression of polypeptides via new gene switch expression systems
WO2018150345A1 (en) * 2017-02-16 2018-08-23 De Vita Bio Life Sciences An expression vector
EP3592368A1 (en) * 2017-03-08 2020-01-15 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of use
JP7216668B2 (ja) * 2017-05-26 2023-02-01 エピセントアールエックス,インコーポレイテッド 導入遺伝子を保持する組換えアデノウイルス
EP3983444A4 (en) * 2019-06-14 2023-10-25 Dana-Farber Cancer Institute, Inc. Antibodies against pd-1 and methods of use thereof
US12071633B2 (en) * 2020-10-13 2024-08-27 Kriya Therapeutics, Inc. Viral vector constructs for delivery of nucleic acids encoding cytokines and uses thereof for treating cancer
CA3235894A1 (en) 2021-10-25 2023-05-04 Brile Chung Compositions and methods for therapeutic delivery

Similar Documents

Publication Publication Date Title
EP3490583B1 (en) Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules
EP3461491B1 (en) Enhanced adoptive cell therapy
Walther et al. Transcriptional regulation of the interferon-beta 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines.
Schmidt et al. Design and structural requirements of the potent and safe TLR-9 agonistic immunomodulator MGN1703
US20050013799A1 (en) Methods of prevention and treatment of asthma, and allergic conditions
WO2017041739A1 (zh) 改造的白介素12及其在制备治疗肿瘤药物中的用途
EP3845646A1 (en) Modified antisense oligonucleotide for inhibition of foxp3 expression
JP5933674B2 (ja) 癌治療用の組合せ製品
JP2024540002A5 (https=)
CN115552019A (zh) 在髓样细胞和小胶质细胞中特异性表达治疗性蛋白的病毒载体
JP2023544142A5 (https=)
JP2024038026A (ja) 活性成分として抗がんウイルス、免疫チェックポイント阻害剤及びヒドロキシ尿素を含む、がんを処置するための医薬組成物
WO2005063290A2 (en) Use of il-18 binding protein in inflammations
JP2023544141A5 (https=)
JP2023512337A (ja) インターロイキン-12とフィブロネクチンのエクストラドメインbに結合する抗体とを含む組換えタンパク質を含む組成物の投与単位およびレジメン、使用、方法または製剤
Montero et al. Immune effects observed after the injection of plasmids coding for rainbow trout (Oncorhynchus mykiss) CK5B, CK6 and CK7A chemokines demonstrate their immunomodulatory capacity and reveal CK6 as a major interferon inducer
Lasek et al. Interleukin 12: Antitumor activity and immunotherapeutic potential in oncology
US20250186551A1 (en) Therapeutic nucleic acid molecule, mixture, and drug, and use thereof in treating solid tumor
EP4460507A2 (en) Methods and compositions for enhancement of tumor immunogenicity and stimulating anti-tumor immune responses in an animal
JP2023521076A5 (https=)
Pahl et al. Protection against Progressive Leishmaniasis
HK40009404B (en) Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules
HK40009404A (en) Oncolytic herpes simplex virus vectors expressing immune system-stimulatory molecules
US20040110696A1 (en) Gene therapy system and method using alpha-msh and its derivatives
Amedei et al. Cancer Immunotherapy: The Share of Cytokines and Chemokines