JP2024539193A - マトリックスメタロプロテイナーゼ７（ＭＭＰ７）の発現を抑制するためのＲＮＡｉ剤、その組成物、及び使用の方法 - Google Patents

マトリックスメタロプロテイナーゼ７（ＭＭＰ７）の発現を抑制するためのＲＮＡｉ剤、その組成物、及び使用の方法 Download PDF

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JP2024539193A
JP2024539193A JP2024523783A JP2024523783A JP2024539193A JP 2024539193 A JP2024539193 A JP 2024539193A JP 2024523783 A JP2024523783 A JP 2024523783A JP 2024523783 A JP2024523783 A JP 2024523783A JP 2024539193 A JP2024539193 A JP 2024539193A
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rnai agent
mmp7
nucleotides
sense strand
antisense strand
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ニコラス アンソニー
ペイ タオ
ダブリュ．ブッシュ エリック
ユアン ティンティン
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アローヘッド ファーマシューティカルズ インコーポレイテッド
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JP2024523783A 2021-10-22 2022-10-21 マトリックスメタロプロテイナーゼ７（ＭＭＰ７）の発現を抑制するためのＲＮＡｉ剤、その組成物、及び使用の方法 Pending JP2024539193A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163270849P 2021-10-22 2021-10-22
US63/270,849 2021-10-22
US202263308289P 2022-02-09 2022-02-09
US63/308,289 2022-02-09
US202263345654P 2022-05-25 2022-05-25
US63/345,654 2022-05-25
PCT/US2022/078498 WO2023070082A2 (en) 2021-10-22 2022-10-21 Rnai agents for inhibiting expression of matrix metalloproteinase 7(mmp7), compositions thereof, and methods of use

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JP2024539193A true JP2024539193A (ja) 2024-10-28
JP2024539193A5 JP2024539193A5 (https=) 2025-10-28

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US (1) US20230265437A1 (https=)
EP (1) EP4419689A2 (https=)
JP (1) JP2024539193A (https=)
KR (1) KR20240099296A (https=)
AU (1) AU2022368927A1 (https=)
CA (1) CA3235224A1 (https=)
CL (1) CL2024001175A1 (https=)
CO (1) CO2024005110A2 (https=)
IL (1) IL312239A (https=)
MX (1) MX2024004912A (https=)
PE (1) PE20241185A1 (https=)
TW (1) TW202334416A (https=)
WO (1) WO2023070082A2 (https=)

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TW202503060A (zh) * 2023-06-13 2025-01-16 大陸商上海拓界生物醫藥科技有限公司 靶向ＭＭＰ７的ｓｉＲＮＡ、ｓｉＲＮＡ綴合物及其醫藥用途
CN121693569A (zh) 2023-07-28 2026-03-17 长春金赛药业有限责任公司 siRNA及其组合物
CN120309596A (zh) * 2024-01-15 2025-07-15 武汉人福创新药物研发中心有限公司 靶向αvβ6的化合物及其用途
WO2025228156A1 (zh) * 2024-04-30 2025-11-06 北京炫景瑞医药科技有限公司 肾靶向的双链寡核苷酸缀合物及其用途

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US20030194704A1 (en) * 2002-04-03 2003-10-16 Penn Sharron Gaynor Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
US20050118625A1 (en) * 2003-10-02 2005-06-02 Mounts William M. Nucleic acid arrays for detecting gene expression associated with human osteoarthritis and human proteases
WO2006092795A2 (en) * 2005-03-01 2006-09-08 Qbi Enterprises Ltd. Oligoribonucleotides and methods of use thereof for treatment of ocular scarring and other fibrotic conditions
WO2019089765A1 (en) * 2017-11-01 2019-05-09 Arrowhead Pharmcaceuticals, Inc. Integrin ligands and uses thereof
US12372530B2 (en) * 2017-11-15 2025-07-29 Beth Israel Deaconess Medical Center, Inc. Markers for the diagnosis and treatment of non-alcoholic steatohepatitis (NASH) and advanced liver fibrosis
CN116783294A (zh) * 2020-09-11 2023-09-19 箭头药业股份有限公司 整联蛋白靶向配体及其用途

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PE20241185A1 (es) 2024-06-03
TW202334416A (zh) 2023-09-01
KR20240099296A (ko) 2024-06-28
US20230265437A1 (en) 2023-08-24
CO2024005110A2 (es) 2024-05-30
WO2023070082A3 (en) 2023-07-06
MX2024004912A (es) 2024-05-06
CL2024001175A1 (es) 2024-12-20
WO2023070082A2 (en) 2023-04-27
EP4419689A2 (en) 2024-08-28
AU2022368927A1 (en) 2024-04-11
CA3235224A1 (en) 2023-04-27
IL312239A (en) 2024-06-01

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