JP2024539068A5 - - Google Patents
Info
- Publication number
- JP2024539068A5 JP2024539068A5 JP2024523187A JP2024523187A JP2024539068A5 JP 2024539068 A5 JP2024539068 A5 JP 2024539068A5 JP 2024523187 A JP2024523187 A JP 2024523187A JP 2024523187 A JP2024523187 A JP 2024523187A JP 2024539068 A5 JP2024539068 A5 JP 2024539068A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridine
- oxazolo
- methyl
- amino
- piperidyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21203314 | 2021-10-19 | ||
| EP21203314.6 | 2021-10-19 | ||
| EP22174872 | 2022-05-23 | ||
| EP22174872.6 | 2022-05-23 | ||
| PCT/EP2022/078755 WO2023066825A1 (en) | 2021-10-19 | 2022-10-17 | Fused bicyclic heteroaryl compounds useful as nlrp3 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024539068A JP2024539068A (ja) | 2024-10-28 |
| JP2024539068A5 true JP2024539068A5 (https=) | 2025-10-09 |
Family
ID=84359071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024523187A Pending JP2024539068A (ja) | 2021-10-19 | 2022-10-17 | Ｎｌｒｐ３阻害剤として有用な縮合二環式ヘテロアリール化合物 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20240279237A1 (https=) |
| EP (1) | EP4419532A1 (https=) |
| JP (1) | JP2024539068A (https=) |
| KR (1) | KR20240088922A (https=) |
| AR (1) | AR127386A1 (https=) |
| AU (1) | AU2022369332A1 (https=) |
| CA (1) | CA3228369A1 (https=) |
| CL (1) | CL2024001106A1 (https=) |
| CO (1) | CO2024004552A2 (https=) |
| CR (1) | CR20240158A (https=) |
| IL (1) | IL310442A (https=) |
| MX (1) | MX2024004503A (https=) |
| PE (1) | PE20241176A1 (https=) |
| TW (1) | TW202330545A (https=) |
| WO (1) | WO2023066825A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| CA3261365A1 (en) * | 2022-07-28 | 2024-02-01 | Ac Immune Sa | NEW COMPOUNDS |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| EP4667468A1 (en) * | 2023-02-14 | 2025-12-24 | Shenzhen Zhongge Biological Technology Co., Ltd. | Compound for inhibiting nlrp3, preparation method, and use |
| AU2024258000A1 (en) | 2023-04-19 | 2025-08-14 | F. Hoffmann-La Roche Ag | Oxazolo[4,5-b]pyrazine and oxazolo[4,5-b]pyridine derivatives as nlrp3 inhibitors for the treatment of e.g. inflammatory diseases |
| WO2025067343A1 (zh) * | 2023-09-27 | 2025-04-03 | 纽欧申医药(上海)有限公司 | 并环化合物及其应用 |
| WO2025099241A1 (en) * | 2023-11-10 | 2025-05-15 | Evotec International Gmbh | Nlrp3 modulators |
| US20250195511A1 (en) * | 2023-12-14 | 2025-06-19 | Merck Sharp & Dohme Llc | Indazole derivatives useful as inhibitors of nod-like receptor protein 3 |
| TW202532066A (zh) * | 2023-12-14 | 2025-08-16 | 美商默沙東有限責任公司 | 作為nod樣受體蛋白3抑制劑之氮雜吲唑衍生物 |
| WO2025146160A1 (zh) * | 2024-01-05 | 2025-07-10 | 北京普祺医药科技股份有限公司 | 杂环化合物及其药物组合物 |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
| WO2025172260A1 (en) * | 2024-02-12 | 2025-08-21 | Evotec International Gmbh | Nlrp3 modulators |
| WO2025172521A1 (en) * | 2024-02-15 | 2025-08-21 | Evotec International Gmbh | Nlrp3 modulators |
| WO2026054623A1 (ko) * | 2024-09-09 | 2026-03-12 | (주) 업테라 | 신규 nlrp3 억제제 화합물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102116166B1 (ko) * | 2017-09-20 | 2020-05-27 | 건국대학교 글로컬산학협력단 | Nlrp3 억제제 |
| EP3953360B1 (en) | 2019-04-09 | 2024-02-28 | F. Hoffmann-La Roche AG | Heterocyclic compounds as inhibitors of monoacylglycerol lipase (magl) |
-
2022
- 2022-10-17 CA CA3228369A patent/CA3228369A1/en active Pending
- 2022-10-17 KR KR1020247012834A patent/KR20240088922A/ko active Pending
- 2022-10-17 EP EP22803219.9A patent/EP4419532A1/en active Pending
- 2022-10-17 MX MX2024004503A patent/MX2024004503A/es unknown
- 2022-10-17 AU AU2022369332A patent/AU2022369332A1/en active Pending
- 2022-10-17 JP JP2024523187A patent/JP2024539068A/ja active Pending
- 2022-10-17 WO PCT/EP2022/078755 patent/WO2023066825A1/en not_active Ceased
- 2022-10-17 AR ARP220102819A patent/AR127386A1/es unknown
- 2022-10-17 IL IL310442A patent/IL310442A/en unknown
- 2022-10-17 PE PE2024000806A patent/PE20241176A1/es unknown
- 2022-10-17 CR CR20240158A patent/CR20240158A/es unknown
- 2022-10-18 TW TW111139412A patent/TW202330545A/zh unknown
-
2024
- 2024-04-11 CL CL2024001106A patent/CL2024001106A1/es unknown
- 2024-04-11 CO CONC2024/0004552A patent/CO2024004552A2/es unknown
- 2024-04-17 US US18/637,966 patent/US20240279237A1/en active Pending
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