JP2024538973A5 - - Google Patents

Info

Publication number
JP2024538973A5
JP2024538973A5 JP2024521169A JP2024521169A JP2024538973A5 JP 2024538973 A5 JP2024538973 A5 JP 2024538973A5 JP 2024521169 A JP2024521169 A JP 2024521169A JP 2024521169 A JP2024521169 A JP 2024521169A JP 2024538973 A5 JP2024538973 A5 JP 2024538973A5
Authority
JP
Japan
Prior art keywords
sequence
reference sequence
pbnj
target sequence
target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024521169A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024538973A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/078666 external-priority patent/WO2023076908A1/en
Publication of JP2024538973A publication Critical patent/JP2024538973A/ja
Publication of JP2024538973A5 publication Critical patent/JP2024538973A5/ja
Pending legal-status Critical Current

Links

JP2024521169A 2021-10-25 2022-10-25 ポリメラーゼ連鎖反応によるターゲット識別を向上させるオフターゲットブロック配列 Pending JP2024538973A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163271522P 2021-10-25 2021-10-25
US63/271,522 2021-10-25
PCT/US2022/078666 WO2023076908A1 (en) 2021-10-25 2022-10-25 Off-target blocking sequences to improve target discrimination by polymerase chain reaction

Publications (2)

Publication Number Publication Date
JP2024538973A JP2024538973A (ja) 2024-10-28
JP2024538973A5 true JP2024538973A5 (https=) 2025-10-30

Family

ID=86158535

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024521169A Pending JP2024538973A (ja) 2021-10-25 2022-10-25 ポリメラーゼ連鎖反応によるターゲット識別を向上させるオフターゲットブロック配列

Country Status (6)

Country Link
US (1) US20230250467A1 (https=)
EP (1) EP4423297A4 (https=)
JP (1) JP2024538973A (https=)
AU (1) AU2022375767A1 (https=)
CA (1) CA3234121A1 (https=)
WO (1) WO2023076908A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250340934A1 (en) * 2024-05-06 2025-11-06 Gt Molecular, Inc. Selective blocking to detect and amplify low abundant template

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7348146B2 (en) * 2003-10-02 2008-03-25 Epoch Biosciences, Inc. Single nucleotide polymorphism analysis of highly polymorphic target sequences
US20110287424A1 (en) * 2009-03-27 2011-11-24 Life Technologies Corporation Methylation-specific competitive allele-specific taqman polymerase chain reaction (cast-pcr)
US9404147B2 (en) * 2011-12-19 2016-08-02 Gen-Probe Incorporated Closed nucleic acid structures
EP2959016A4 (en) * 2013-02-21 2016-10-12 Toma Biosciences Inc METHOD, COMPOSITIONS AND NUCLEIC ACID ANALYSIS KITS
CN114959098A (zh) * 2016-07-01 2022-08-30 嘉士伯有限公司 通过应用混合分裂方法筛选生物群体内突变体的方法
WO2022192732A1 (en) * 2021-03-12 2022-09-15 Gt Molecular, Llc Multiplexed genotyping assays with a single probe using fluorescent amplitude tuning

Similar Documents

Publication Publication Date Title
AU2022226186A1 (en) Methods for detection of donor-derived cell-free dna in transplant recipients of multiple organs
AU2022237538A1 (en) Methods for determination of transplant rejection
US20240410000A1 (en) Hla gene amplification primer, kit, sequencing library establishment method, and sequencing method
CN110964814B (zh) 用于核酸序列变异检测的引物、组合物及方法
CN113930500B (zh) 人pik3ca基因突变的数字pcr检测方法及应用
WO2005072133A2 (en) Nucleic acid detection
CN110392739B (zh) 检测dna突变的测序方法
EP4237584B1 (en) Generic cartridge and method for multiplex nucleic acid detection
AU2015213570B2 (en) NGS systems control and methods involving the same
CN108456721B (zh) 同步检测基因突变和甲基化的方法及其应用
US20010039012A1 (en) Methods for diagnostic screening
CN113308519B (zh) 用于检测单碱基突变位点的引物和探针及检测方法
JP2002027993A (ja) 特定の核酸を検出定量するための等長プライマー伸長法およびキット
JP2024538973A5 (https=)
JP5258760B2 (ja) メチル化核酸又は非メチル化核酸を増幅する方法
US8367814B2 (en) Assay for BCR/ABL gene rearrangement
US20230250467A1 (en) Off-target blocking sequences to improve target discrimination by polymerase chain reaction
JPWO2005021743A1 (ja) 核酸増幅用プライマー及びこれを用いた大腸癌の検査方法
US20230250472A1 (en) Digital method for analyzing nucleic acids in samples
Zhang et al. Multiplex one-step direct asymmetric PCR of blood and dual-labelled probe-mediated melting curve for genotyping of MTHFR and MTRR polymorphisms
CN116783308A (zh) 用于多重核酸检测的通用卡盒和方法
JP2982304B2 (ja) 核酸の識別方法及び核酸の識別用検査セット
JP7461624B2 (ja) B型肝炎ワクチンに対する免疫応答性の遺伝的要因を検出する方法及びキット
CN119570953A (zh) 利用荧光pcr毛细管电泳技术检测猪亲缘关系及个体识别的检测试剂盒及其应用
KR20260035341A (ko) 인간 유래 세포를 검출하기 위한 AluYb9 올리고 뉴클레오티드 프라이머 세트 및 이의 용도