JP2024536362A5 - - Google Patents
Info
- Publication number
- JP2024536362A5 JP2024536362A5 JP2024520693A JP2024520693A JP2024536362A5 JP 2024536362 A5 JP2024536362 A5 JP 2024536362A5 JP 2024520693 A JP2024520693 A JP 2024520693A JP 2024520693 A JP2024520693 A JP 2024520693A JP 2024536362 A5 JP2024536362 A5 JP 2024536362A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- alkylene
- independently
- cooh
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21200719 | 2021-10-04 | ||
| EP21200719.9 | 2021-10-04 | ||
| EP22151771.7 | 2022-01-17 | ||
| EP22151771 | 2022-01-17 | ||
| PCT/EP2022/077598 WO2023057457A1 (en) | 2021-10-04 | 2022-10-04 | Radiolabelled fibroblast activation protein ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024536362A JP2024536362A (ja) | 2024-10-04 |
| JP2024536362A5 true JP2024536362A5 (enExample) | 2025-10-15 |
Family
ID=84330437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024520693A Pending JP2024536362A (ja) | 2021-10-04 | 2022-10-04 | 放射標識化された線維芽細胞活性化タンパク質リガンド |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4412996A1 (enExample) |
| JP (1) | JP2024536362A (enExample) |
| KR (1) | KR20240093543A (enExample) |
| AU (1) | AU2022358921A1 (enExample) |
| CA (1) | CA3234394A1 (enExample) |
| IL (1) | IL311694A (enExample) |
| MX (1) | MX2024004077A (enExample) |
| WO (1) | WO2023057457A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202426433A (zh) | 2022-09-23 | 2024-07-01 | 瑞士商紐利迪姆股份公司 | 成纖維細胞活化蛋白（ｆａｐ）抑制劑、ｆａｐ結合物及其診斷與治療用途 |
| KR20250073273A (ko) * | 2022-09-23 | 2025-05-27 | 누클리디움 아게 | 고순도 구리 방사성 의약 조성물 및 이의 진단 및 치료 용도 |
| CN120957982A (zh) | 2023-05-08 | 2025-11-14 | 江苏恒瑞医药股份有限公司 | 靶向成纤维细胞活化蛋白的配体 |
| CN116925041B (zh) * | 2023-06-12 | 2024-12-24 | 上海交通大学医学院附属仁济医院 | 靶向成纤维细胞激活蛋白的氟标记放射性药物前体、放射性标记化合物及其应用 |
| CN120136958A (zh) * | 2023-12-13 | 2025-06-13 | 无锡诺宇医药科技有限公司 | Fap靶向放射性药物 |
| WO2025167951A1 (zh) * | 2024-02-07 | 2025-08-14 | 苏州博锐创合医药有限公司 | 一种成纤维细胞活化蛋白抑制剂 |
| TW202600606A (zh) * | 2024-02-21 | 2026-01-01 | 美商雅博得樂醫療公司 | 抗體連接子結合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005087235A1 (en) | 2004-03-09 | 2005-09-22 | National Health Research Institutes | Pyrrolidine compounds |
| WO2013107820A1 (en) | 2012-01-17 | 2013-07-25 | Universiteit Antwerpen | Novel fap inhibitors |
| CN116474108A (zh) | 2016-12-14 | 2023-07-25 | 普渡研究基金会 | 成纤维细胞活化蛋白(fap)-靶向成像和治疗 |
| EA202090776A1 (ru) | 2017-10-23 | 2020-07-27 | Дзе Джонс Хопкинс Юниверсити | Визуализирующие и радиотерапевтические агенты, нацеленные на фибробласт-активирующий белок-альфа (fapalpha) |
| US11780821B2 (en) | 2017-12-15 | 2023-10-10 | Praxis Biotech LLC | Inhibitors of fibroblast activation protein |
| EP3749663A1 (en) | 2018-02-06 | 2020-12-16 | Universität Heidelberg | Fap inhibitor |
| WO2019154859A1 (en) | 2018-02-06 | 2019-08-15 | Universität Heidelberg | Fap inhibitor |
| EP4019507A1 (en) * | 2020-02-12 | 2022-06-29 | Philochem AG | Fibroblast activation protein ligands for targeted delivery applications |
-
2022
- 2022-10-04 KR KR1020247015053A patent/KR20240093543A/ko active Pending
- 2022-10-04 MX MX2024004077A patent/MX2024004077A/es unknown
- 2022-10-04 WO PCT/EP2022/077598 patent/WO2023057457A1/en not_active Ceased
- 2022-10-04 JP JP2024520693A patent/JP2024536362A/ja active Pending
- 2022-10-04 CA CA3234394A patent/CA3234394A1/en active Pending
- 2022-10-04 IL IL311694A patent/IL311694A/en unknown
- 2022-10-04 AU AU2022358921A patent/AU2022358921A1/en active Pending
- 2022-10-04 EP EP22801357.9A patent/EP4412996A1/en active Pending
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