IL311694A - Radiolabelled fibroblast activation protein ligands - Google Patents
Radiolabelled fibroblast activation protein ligandsInfo
- Publication number
- IL311694A IL311694A IL311694A IL31169424A IL311694A IL 311694 A IL311694 A IL 311694A IL 311694 A IL311694 A IL 311694A IL 31169424 A IL31169424 A IL 31169424A IL 311694 A IL311694 A IL 311694A
- Authority
- IL
- Israel
- Prior art keywords
- radiolabelled
- activation protein
- fibroblast activation
- protein ligands
- ligands
- Prior art date
Links
- 230000004913 activation Effects 0.000 title 1
- 210000002950 fibroblast Anatomy 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/06—Aluminium compounds
- C07F5/069—Aluminium compounds without C-aluminium linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21200719 | 2021-10-04 | ||
| EP22151771 | 2022-01-17 | ||
| PCT/EP2022/077598 WO2023057457A1 (en) | 2021-10-04 | 2022-10-04 | Radiolabelled fibroblast activation protein ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL311694A true IL311694A (en) | 2024-05-01 |
Family
ID=84330437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL311694A IL311694A (en) | 2021-10-04 | 2022-10-04 | Radiolabelled fibroblast activation protein ligands |
Country Status (4)
| Country | Link |
|---|---|
| AU (1) | AU2022358921A1 (en) |
| CA (1) | CA3234394A1 (en) |
| IL (1) | IL311694A (en) |
| WO (1) | WO2023057457A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240189460A1 (en) * | 2022-09-23 | 2024-06-13 | Nuclidium Ag | High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof |
| CN116925041A (en) * | 2023-06-12 | 2023-10-24 | 上海交通大学医学院附属仁济医院 | Fluorine-labeled radiopharmaceuticals precursors, radiolabeled compounds, and uses thereof, targeting fibroblast activation proteins |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100844593B1 (en) | 2004-03-09 | 2008-07-07 | 내셔날 헬스 리서치 인스티튜트 | Pyrrolidine compounds |
| EP2804859B1 (en) | 2012-01-17 | 2019-06-12 | Universiteit Antwerpen | Novel fap inhibitors |
| WO2018111989A1 (en) | 2016-12-14 | 2018-06-21 | Purdue Research Foundation | Fibroblast activation protein (fap)-targeted imaging and therapy |
| MX2020004807A (en) | 2017-10-23 | 2020-10-05 | Univ Johns Hopkins | Imaging and radiotherapeutics agents targeting fibroblast-activation protein-¿ (fap-¿). |
| WO2019118932A1 (en) | 2017-12-15 | 2019-06-20 | Praxis Biotech LLC | Inhibitors of fibroblast activation protein |
| WO2019154859A1 (en) | 2018-02-06 | 2019-08-15 | Universität Heidelberg | Fap inhibitor |
| JP2021512949A (en) | 2018-02-06 | 2021-05-20 | ウニベルジテート ハイデルベルク | FAP inhibitor |
| EP3891138B1 (en) * | 2020-02-12 | 2022-01-12 | Philochem AG | Fibroblast activation protein ligands for targeted delivery applications |
-
2022
- 2022-10-04 WO PCT/EP2022/077598 patent/WO2023057457A1/en active Application Filing
- 2022-10-04 CA CA3234394A patent/CA3234394A1/en active Pending
- 2022-10-04 IL IL311694A patent/IL311694A/en unknown
- 2022-10-04 AU AU2022358921A patent/AU2022358921A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2022358921A1 (en) | 2024-05-02 |
| CA3234394A1 (en) | 2023-04-13 |
| WO2023057457A1 (en) | 2023-04-13 |
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