JP2024535354A - がん治療組成物およびその使用 - Google Patents

がん治療組成物およびその使用 Download PDF

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JP2024535354A
JP2024535354A JP2024518367A JP2024518367A JP2024535354A JP 2024535354 A JP2024535354 A JP 2024535354A JP 2024518367 A JP2024518367 A JP 2024518367A JP 2024518367 A JP2024518367 A JP 2024518367A JP 2024535354 A JP2024535354 A JP 2024535354A
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composition
nucleic acid
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cancer
bis
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JP2024535354A5 (https=
Inventor
スティーブン グレゴリー リード，
ダリック アルバート カーター，
マルコルム スコット ダシー，
ラース ピーター アクセル バーグランド，
ジェシー ホン－セ エラスムス，
ジホ キム，
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エイチディーティー バイオ コーポレーション
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Publication of JP2024535354A5 publication Critical patent/JP2024535354A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A61K39/001156—Tyrosinase and tyrosinase related proteinases [TRP-1 or TRP-2]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186—MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001193—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; PAP or PSGR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
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    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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    • A61K2039/53—DNA (RNA) vaccination
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    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Virology (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2024518367A 2021-09-22 2022-09-12 がん治療組成物およびその使用 Pending JP2024535354A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163247167P 2021-09-22 2021-09-22
US63/247,167 2021-09-22
US202263302360P 2022-01-24 2022-01-24
US63/302,360 2022-01-24
PCT/US2022/076304 WO2023049636A2 (en) 2021-09-22 2022-09-12 Cancer therapy compositions and uses thereof

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Publication Number Publication Date
JP2024535354A true JP2024535354A (ja) 2024-09-30
JP2024535354A5 JP2024535354A5 (https=) 2025-09-24

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ID=85721230

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JP2024518367A Pending JP2024535354A (ja) 2021-09-22 2022-09-12 がん治療組成物およびその使用

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US (2) US12485163B2 (https=)
EP (1) EP4404957A4 (https=)
JP (1) JP2024535354A (https=)
KR (1) KR20240111819A (https=)
AU (1) AU2022348995A1 (https=)
CA (1) CA3232725A1 (https=)
WO (1) WO2023049636A2 (https=)

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JP2024535354A (ja) 2021-09-22 2024-09-30 エイチディーティー バイオ コーポレーション がん治療組成物およびその使用
EP4404919A4 (en) 2021-09-22 2025-08-20 Hdt Bio Corp DRIED NANOPARTICLE COMPOSITIONS
CA3232719A1 (en) 2021-09-22 2023-03-30 Steven Gregory REED Sars-cov-2 rna vaccine compositions and methods of use
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WO2026039538A1 (en) * 2024-08-14 2026-02-19 Trishula Therapeutics, Inc. Methods of treating pancreatic tumors expressing certain biomarkers

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