JP2024532845A5 - - Google Patents
Info
- Publication number
- JP2024532845A5 JP2024532845A5 JP2024510224A JP2024510224A JP2024532845A5 JP 2024532845 A5 JP2024532845 A5 JP 2024532845A5 JP 2024510224 A JP2024510224 A JP 2024510224A JP 2024510224 A JP2024510224 A JP 2024510224A JP 2024532845 A5 JP2024532845 A5 JP 2024532845A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- optionally substituted
- substituted
- cancer
- alternatively
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2021/112906 | 2021-08-17 | ||
| CN2021112906 | 2021-08-17 | ||
| PCT/CN2022/112674 WO2023020457A1 (en) | 2021-08-17 | 2022-08-16 | Pyridazinone or pyridinone compounds, preparation methods and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024532845A JP2024532845A (ja) | 2024-09-10 |
| JP2024532845A5 true JP2024532845A5 (enExample) | 2025-08-13 |
Family
ID=85240081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024510224A Pending JP2024532845A (ja) | 2021-08-17 | 2022-08-16 | ピリダジノンまたはピリジノン化合物、その製造方法および用途 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240343727A1 (enExample) |
| EP (1) | EP4387966A4 (enExample) |
| JP (1) | JP2024532845A (enExample) |
| CN (1) | CN117897380A (enExample) |
| WO (1) | WO2023020457A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4423078A1 (en) * | 2021-10-28 | 2024-09-04 | Gilead Sciences, Inc. | Pyridizin-3(2h)-one derivatives |
| CN119968364A (zh) * | 2022-09-30 | 2025-05-09 | 阿兹卡拉疗法公司 | 哒嗪-3(2h)-酮和吡啶-2(1h)-酮parp抑制剂化合物 |
| GB202217888D0 (en) * | 2022-11-29 | 2023-01-11 | Duke Street Bio Ltd | Pharmaceutical compound |
| TW202430518A (zh) * | 2023-01-06 | 2024-08-01 | 大陸商齊魯製藥有限公司 | Parp7抑制劑的製備方法 |
| CN116874496B (zh) * | 2023-07-10 | 2025-07-25 | 东南大学 | 三环类化合物及其制备方法、药物组合物和应用 |
| CN117777099A (zh) * | 2023-12-26 | 2024-03-29 | 诺沃斯达药业(上海)有限公司 | Parp7抑制剂及其用途 |
| CN118772063B (zh) * | 2024-07-04 | 2025-06-13 | 西北师范大学 | 一种四氢哒嗪类化合物的合成方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19921567A1 (de) * | 1999-05-11 | 2000-11-16 | Basf Ag | Verwendung von Phthalazine-Derivaten |
| KR20070057859A (ko) * | 2004-08-26 | 2007-06-07 | 쿠도스 파마슈티칼스 리미티드 | 4-헤테로아릴메틸 치환된 프탈라지논 유도체 |
| GB0419072D0 (en) * | 2004-08-26 | 2004-09-29 | Kudos Pharm Ltd | Phthalazinone derivatives |
| GB0610680D0 (en) * | 2006-05-31 | 2006-07-12 | Istituto Di Ricerche D Biolog | Therapeutic compounds |
| US8466150B2 (en) * | 2006-12-28 | 2013-06-18 | Abbott Laboratories | Inhibitors of poly(ADP-ribose)polymerase |
| AR070221A1 (es) * | 2008-01-23 | 2010-03-25 | Astrazeneca Ab | Derivados de ftalazinona inhibidores de polimerasas, composiciones farmaceuticas que los contienen y usos de los mismos para prevenir y/o tratar tumores cancerigenos,lesiones isquemicas y otras enfermedades asociadas. |
| CN103130723B (zh) * | 2011-11-30 | 2015-01-14 | 成都地奥制药集团有限公司 | 一种多聚(adp-核糖)聚合酶抑制剂 |
| CN106946792B (zh) * | 2017-03-29 | 2019-07-26 | 深圳市坤健创新药物研究院 | 一种酞嗪酮的异羟肟酸衍生物及其制备方法与应用 |
| EP3737361A4 (en) * | 2018-01-11 | 2021-08-25 | Centaurus Therapeutics | INHIBITORS OF DIHYDROCERAMIDE DESATURASE FOR THE TREATMENT OF DISEASES |
| BR112020022006A2 (pt) * | 2018-04-30 | 2021-01-26 | Ribon Therapeutics Inc. | piridazinonas como inibidores de parp7 |
| CN119552152A (zh) * | 2018-10-12 | 2025-03-04 | 益方生物科技(上海)股份有限公司 | 甲状腺激素受体激动剂 |
| WO2021087018A1 (en) * | 2019-10-30 | 2021-05-06 | Ribon Therapeutics, Inc. | Pyridazinones as parp7 inhibitors |
| CN115477640A (zh) * | 2021-05-31 | 2022-12-16 | 由理生物医药（上海）有限公司 | 作为parp7抑制剂的哒嗪酮类化合物 |
-
2022
- 2022-08-16 CN CN202280055111.5A patent/CN117897380A/zh active Pending
- 2022-08-16 JP JP2024510224A patent/JP2024532845A/ja active Pending
- 2022-08-16 WO PCT/CN2022/112674 patent/WO2023020457A1/en not_active Ceased
- 2022-08-16 US US18/578,677 patent/US20240343727A1/en active Pending
- 2022-08-16 EP EP22857769.8A patent/EP4387966A4/en active Pending
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