JP2024529506A5 - - Google Patents

Info

Publication number
JP2024529506A5
JP2024529506A5 JP2024505498A JP2024505498A JP2024529506A5 JP 2024529506 A5 JP2024529506 A5 JP 2024529506A5 JP 2024505498 A JP2024505498 A JP 2024505498A JP 2024505498 A JP2024505498 A JP 2024505498A JP 2024529506 A5 JP2024529506 A5 JP 2024529506A5
Authority
JP
Japan
Prior art keywords
substituted
seq
sequence
chain
nectin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024505498A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024529506A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/038720 external-priority patent/WO2023009751A2/en
Publication of JP2024529506A publication Critical patent/JP2024529506A/ja
Publication of JP2024529506A5 publication Critical patent/JP2024529506A5/ja
Pending legal-status Critical Current

Links

JP2024505498A 2021-07-30 2022-07-28 ネクチン-4に特異的な抗体および抗体複合体、並びにそれらの使用方法 Pending JP2024529506A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163227666P 2021-07-30 2021-07-30
US63/227,666 2021-07-30
US202263322914P 2022-03-23 2022-03-23
US63/322,914 2022-03-23
US202263344932P 2022-05-23 2022-05-23
US63/344,932 2022-05-23
PCT/US2022/038720 WO2023009751A2 (en) 2021-07-30 2022-07-28 Antibodies and antibody conjugates specific for nectin-4 and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024529506A JP2024529506A (ja) 2024-08-06
JP2024529506A5 true JP2024529506A5 (enExample) 2025-10-15

Family

ID=85088249

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2024505116A Pending JP2024529466A (ja) 2021-07-30 2022-07-28 抗体薬物コンジュゲート及びその使用方法
JP2024505498A Pending JP2024529506A (ja) 2021-07-30 2022-07-28 ネクチン-4に特異的な抗体および抗体複合体、並びにそれらの使用方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2024505116A Pending JP2024529466A (ja) 2021-07-30 2022-07-28 抗体薬物コンジュゲート及びその使用方法

Country Status (9)

Country Link
US (2) US20250121090A1 (enExample)
EP (3) EP4377320A4 (enExample)
JP (2) JP2024529466A (enExample)
KR (2) KR20240049858A (enExample)
AU (2) AU2022319782A1 (enExample)
CA (2) CA3227844A1 (enExample)
IL (1) IL310432A (enExample)
MX (2) MX2024001396A (enExample)
WO (3) WO2023009759A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250121090A1 (en) * 2021-07-30 2025-04-17 R.P. Scherer Technologies, Llc Antibody-Drug Conjugates and Methods of Use Thereof
KR20250161707A (ko) * 2024-05-08 2025-11-18 아주대학교산학협력단 Nectin-2에 결합하는 항체 약물 접합체 및 이의 용도

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX369148B (es) * 2012-09-19 2019-10-30 Innate Pharma Agentes de unión kir3dl2.
US9310374B2 (en) * 2012-11-16 2016-04-12 Redwood Bioscience, Inc. Hydrazinyl-indole compounds and methods for producing a conjugate
CN115504924A (zh) * 2013-11-27 2022-12-23 雷德伍德生物科技股份有限公司 肼基-吡咯并化合物及用于生成缀合物的方法
EP3373937B1 (en) * 2015-11-09 2021-12-22 R.P. Scherer Technologies, LLC Anti-cd22 antibody-maytansine conjugates and methods of use thereof
KR102127421B1 (ko) * 2017-03-21 2020-06-26 주식회사 펩트론 Muc1에 특이적으로 결합하는 항체 및 그의 용도
WO2019113248A1 (en) * 2017-12-07 2019-06-13 The Regents Of The University Of California Anti-upar antibody-drug conjugates and methods of use thereof
KR20200117992A (ko) * 2017-12-11 2020-10-14 트리페이스 리서치 앤드 디벨로프먼트 쓰리 코포레이션 항-cd22 항체-메이탄신 컨쥬게이트, 그것의 조합, 및 사용 방법
KR102896085B1 (ko) * 2018-01-15 2025-12-08 스티흐팅 산퀸 불드포르지닝 인자 h 강화 항체 및 이의 사용
KR102892725B1 (ko) * 2018-05-09 2025-12-01 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디. 인간 넥틴4에 특이적인 항체
CN119896746A (zh) * 2019-01-23 2025-04-29 R.P.谢勒技术有限责任公司 用于抗体-药物缀合物的含有糖苷的肽接头
US20250121090A1 (en) * 2021-07-30 2025-04-17 R.P. Scherer Technologies, Llc Antibody-Drug Conjugates and Methods of Use Thereof

Similar Documents

Publication Publication Date Title
JP7854016B2 (ja) 腫瘍治療薬及びその応用
JP2022065174A5 (enExample)
JP2024529506A5 (enExample)
JP2022064924A5 (enExample)
EP2552959B1 (en) Antibodies to muc16 and methods of use thereof
CN113301920B (zh) 包含配体、间隔物、肽接头和生物分子的复合物
JP2018502050A5 (enExample)
TW201918263A (zh) 抗體-藥物結合物之改良製造方法
JP2020500016A5 (enExample)
RU2015101803A (ru) Перекрестно реактивные антитела к jagged 1/k jagged 2, активируемые антитела к jagged и способы их применения
JP2021524270A5 (enExample)
AU2017320913A1 (en) Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates
JP7360766B2 (ja) 抗ヒトMUC1抗体Fabフラグメント、ペプチドリンカー及び/又は配位子を含む複合体
WO2023168384A2 (en) Methods of treating cancer using multi-specific binding proteins that bind nkg2d, cd16, and her2
DK1086137T3 (da) Sammensætning og fremgangsmåde til at modulere dendritisk T-celle cellevekselvirkning
KR20220151630A (ko) 신규 고리형 디뉴클레오티드 유도체를 포함하는 항체 약물 컨쥬게이트
RU2019129839A (ru) Производные майтанзиноида с саморасщепляющимися пептидными линкерами и их конъюгаты
JP2024508808A5 (enExample)
WO2019036433A2 (en) ANTIBODIES IN THE FORM OF PRODRUGS, PRODRUGS BASED THEREON, THEIR METHODS OF USE AND PREPARATION
JPWO2020032165A1 (ja) ビオチン改変二量体とフタロシアニン染料とのコンジュゲート
AU2022234694A9 (en) Compound or salt thereof, and antibody obtained using same
CN115916839A (zh) 抗pdl1×egfr的双特异性抗体
JP2024542944A5 (enExample)
JP2024536383A5 (enExample)
WO2025036480A1 (zh) 化合物以及含有该化合物的抗体偶联药物