JP2024529068A5 - - Google Patents
Info
- Publication number
- JP2024529068A5 JP2024529068A5 JP2024507166A JP2024507166A JP2024529068A5 JP 2024529068 A5 JP2024529068 A5 JP 2024529068A5 JP 2024507166 A JP2024507166 A JP 2024507166A JP 2024507166 A JP2024507166 A JP 2024507166A JP 2024529068 A5 JP2024529068 A5 JP 2024529068A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- cancer
- heterocyclyl
- general formula
- compound represented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110913249 | 2021-08-10 | ||
| CN202110913249.1 | 2021-08-10 | ||
| CN202111142090.4 | 2021-09-28 | ||
| CN202111142090 | 2021-09-28 | ||
| CN202111500231 | 2021-12-09 | ||
| CN202111500231.5 | 2021-12-09 | ||
| PCT/CN2022/111395 WO2023016484A1 (zh) | 2021-08-10 | 2022-08-10 | 磺酰胺衍生物、其制备方法及其在医药上的应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024529068A JP2024529068A (ja) | 2024-08-01 |
| JP2024529068A5 true JP2024529068A5 (enExample) | 2025-08-19 |
Family
ID=85200573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024507166A Pending JP2024529068A (ja) | 2021-08-10 | 2022-08-10 | スルファミド誘導体、その調製方法及びその医薬的使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250145637A1 (enExample) |
| EP (1) | EP4385989A4 (enExample) |
| JP (1) | JP2024529068A (enExample) |
| KR (1) | KR20240046530A (enExample) |
| CN (1) | CN117597341A (enExample) |
| AU (1) | AU2022325367A1 (enExample) |
| CA (1) | CA3228411A1 (enExample) |
| MX (1) | MX2024001777A (enExample) |
| TW (1) | TW202321263A (enExample) |
| WO (1) | WO2023016484A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023088233A1 (en) | 2021-11-16 | 2023-05-25 | Insilico Medicine Ip Limited | Lysine acetyltransferase 6a (kat6a) inhibitors and uses thereof |
| CA3241874A1 (en) * | 2021-12-13 | 2023-06-22 | Aurigene Oncology Limited | Fused benzoisoxazolyl compounds as kat6a inhibitors |
| CN116621859A (zh) * | 2022-02-18 | 2023-08-22 | 山东轩竹医药科技有限公司 | 三并环类kat6抑制剂 |
| AU2023241822A1 (en) | 2022-03-28 | 2024-09-26 | Isosterix, Inc. | Inhibitors of the myst family of lysine acetyl transferases |
| AU2024217108A1 (en) * | 2023-02-10 | 2025-09-18 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Crystalline form of sulfonamide derivative and preparation method therefor |
| CN120917003A (zh) | 2023-03-16 | 2025-11-07 | 奥列马制药公司 | 酰基磺酰胺kat6a抑制剂 |
| WO2024201334A1 (en) * | 2023-03-30 | 2024-10-03 | Pfizer Inc. | Kat6a as a predictive biomarker for treatment with a kat6a inhibitor and methods of treatment thereof |
| WO2025007873A1 (zh) | 2023-07-04 | 2025-01-09 | 上海齐鲁制药研究中心有限公司 | Kat6抑制剂 |
| WO2025098417A1 (zh) * | 2023-11-08 | 2025-05-15 | 再和医药科技（苏州）有限公司 | 磺酰胺类化合物及其应用 |
| US20250161289A1 (en) * | 2023-11-10 | 2025-05-22 | Prelude Therapeutics Incorporated | KAT6 Targeting Compounds |
| WO2025136811A1 (en) * | 2023-12-18 | 2025-06-26 | Ideaya Biosciences, Inc. | Chemical compounds and uses thereof |
| WO2026086887A1 (zh) * | 2024-10-23 | 2026-04-30 | 江苏恒瑞医药股份有限公司 | Kat6抑制剂与ar protac的联合 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
| ES2188584T3 (es) * | 1991-03-28 | 2003-07-01 | Eisai Co Ltd | Derivados heterociclicos de amina. |
| WO2002074746A1 (en) * | 2001-03-16 | 2002-09-26 | Yamanouchi Pharmaceutical Co., Ltd. | Benzazepine derivatives |
| AU2003215380B2 (en) * | 2002-02-22 | 2008-10-02 | Bayer Pharmaceuticals Corporation | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders |
| AU2006281803B9 (en) * | 2005-08-18 | 2013-05-30 | Genmab A/S | Therapy with CD4 binding peptides and radiation |
| CN105492430B (zh) * | 2013-03-15 | 2017-10-10 | 基因泰克公司 | 取代的苯并噁唑及其使用方法 |
| WO2015102929A1 (en) * | 2013-12-30 | 2015-07-09 | Novartis Ag | Tricyclic sulfonamide derivatives |
| TWI705967B (zh) * | 2014-03-20 | 2020-10-01 | 美商卡佩拉醫療公司 | 苯并咪唑衍生物及其醫藥組合物及使用方法 |
| GB201510019D0 (en) | 2015-06-09 | 2015-07-22 | Cancer Therapeutics Crc Pty Ltd | Compounds |
| US10787430B2 (en) | 2016-06-17 | 2020-09-29 | Fronthera U.S. Pharmaceuticals Llc | Hemoglobin modifier compounds and uses thereof |
| GB201713962D0 (en) | 2017-08-31 | 2017-10-18 | Ctxt Pty Ltd | Compounds |
| US11685732B2 (en) | 2017-11-29 | 2023-06-27 | Epizyme, Inc. | MYST family histone acetyltransferase inhibitors |
| GB201810092D0 (en) * | 2018-06-20 | 2018-08-08 | Ctxt Pty Ltd | Compounds |
| GB201810581D0 (en) | 2018-06-28 | 2018-08-15 | Ctxt Pty Ltd | Compounds |
| WO2020048548A1 (zh) * | 2018-09-07 | 2020-03-12 | 正大天晴药业集团股份有限公司 | 一种作用于crbn蛋白的三并环类化合物 |
| EA202092908A1 (ru) | 2018-09-28 | 2021-05-14 | Праксис Пресижн Медсинз, Инк. | Модуляторы ионных каналов |
| CN114072394A (zh) | 2019-04-25 | 2022-02-18 | 拜耳股份公司 | 用于治疗癌症的酰基磺酰胺 |
| PH12021553107A1 (en) * | 2019-06-18 | 2022-08-01 | Ctxt Pty Ltd | Benzisoxazole sulfonamide derivatives |
| AU2020295006B2 (en) * | 2019-06-19 | 2023-11-09 | Ctxt Pty Ltd | Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives |
-
2022
- 2022-08-10 JP JP2024507166A patent/JP2024529068A/ja active Pending
- 2022-08-10 WO PCT/CN2022/111395 patent/WO2023016484A1/zh not_active Ceased
- 2022-08-10 CN CN202280046780.6A patent/CN117597341A/zh active Pending
- 2022-08-10 CA CA3228411A patent/CA3228411A1/en active Pending
- 2022-08-10 EP EP22855464.8A patent/EP4385989A4/en active Pending
- 2022-08-10 US US18/682,647 patent/US20250145637A1/en active Pending
- 2022-08-10 TW TW111130097A patent/TW202321263A/zh unknown
- 2022-08-10 KR KR1020247007144A patent/KR20240046530A/ko active Pending
- 2022-08-10 AU AU2022325367A patent/AU2022325367A1/en active Pending
- 2022-08-10 MX MX2024001777A patent/MX2024001777A/es unknown