JP2024525150A5 - - Google Patents

Info

Publication number
JP2024525150A5
JP2024525150A5 JP2023577130A JP2023577130A JP2024525150A5 JP 2024525150 A5 JP2024525150 A5 JP 2024525150A5 JP 2023577130 A JP2023577130 A JP 2023577130A JP 2023577130 A JP2023577130 A JP 2023577130A JP 2024525150 A5 JP2024525150 A5 JP 2024525150A5
Authority
JP
Japan
Prior art keywords
groups
group
unsubstituted
substituted
alkyloxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577130A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525150A (ja
Filing date
Publication date
Priority claimed from EP21315095.6A external-priority patent/EP4105218A1/en
Application filed filed Critical
Priority claimed from PCT/EP2022/066231 external-priority patent/WO2022263472A1/en
Publication of JP2024525150A publication Critical patent/JP2024525150A/ja
Publication of JP2024525150A5 publication Critical patent/JP2024525150A5/ja
Pending legal-status Critical Current

Links

JP2023577130A 2021-06-15 2022-06-14 置換ピロロ［２，３－ｄ］ピリミジン類、それらの製造及びそれらの治療適用 Pending JP2024525150A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP21315095.6 2021-06-15
EP21315095.6A EP4105218A1 (en) 2021-06-15 2021-06-15 Substituted pyrrolo[2,3-d] pyrimidines, their preparation and their therapeutic application
EP22315117 2022-06-02
EP22315117.6 2022-06-02
PCT/EP2022/066231 WO2022263472A1 (en) 2021-06-15 2022-06-14 Substituted pyrrolo[2,3-d]pyrimidines, their preparation and their therapeutic application

Publications (2)

Publication Number Publication Date
JP2024525150A JP2024525150A (ja) 2024-07-10
JP2024525150A5 true JP2024525150A5 (https=) 2025-06-12

Family

ID=82214141

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577130A Pending JP2024525150A (ja) 2021-06-15 2022-06-14 置換ピロロ［２，３－ｄ］ピリミジン類、それらの製造及びそれらの治療適用

Country Status (11)

Country Link
US (1) US20240383901A1 (https=)
EP (1) EP4355748A1 (https=)
JP (1) JP2024525150A (https=)
KR (1) KR20240021910A (https=)
AU (1) AU2022294022A1 (https=)
BR (1) BR112023025042A2 (https=)
CA (1) CA3223786A1 (https=)
CO (1) CO2024000083A2 (https=)
IL (1) IL309195A (https=)
MX (1) MX2023015016A (https=)
WO (1) WO2022263472A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025141029A1 (en) * 2023-12-27 2025-07-03 Sanofi Substituted pyrrolo[2,3-d]pyrimidines, their preparation and their therapeutic application
KR20250163526A (ko) 2024-05-14 2025-11-21 김성우 음전하 증폭장치가 장착된 어싱용 발판

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2988722B1 (fr) * 2012-04-03 2014-05-09 Sanofi Sa Nouveaux derives de thienopyrimidines, leurs procedes de preparation et leurs utilisations therapeutiques
CN106146515B (zh) * 2015-04-17 2020-09-04 常州隆赛医药科技有限公司 新型激酶抑制剂的制备及应用
US11214565B2 (en) * 2015-11-20 2022-01-04 Denali Therapeutics Inc. Compound, compositions, and methods
JP2018537502A (ja) * 2015-12-16 2018-12-20 サウザーン リサーチ インスチチュート ピロロピリミジン化合物、キナーゼｌｒｒｋ２阻害剤としての使用、及びその調製方法
EP3587422A4 (en) 2017-02-22 2020-05-06 Daegu-Gyeongbuk Medical Innovation Foundation PYRROLOPYRIMIDINE DERIVATIVE COMPOUND, PRODUCTION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION WITH THIS COMPOUND AS AN ACTIVE SUBSTANCE FOR PREVENTING OR TREATING PROTEIN KINASE-RELATED DISEASE
WO2020092136A1 (en) * 2018-10-31 2020-05-07 Merck Sharp & Dohme Corp. N-heteroaryl indazole derivatives as lrrk2 inhibitors, pharmaceutical compositions, and uses thereof
EP3915985A4 (en) 2019-01-18 2022-09-28 Voronoi Co., Ltd. PYRROLOPYRIDE DERIVATIVE AND USE THEREOF FOR THE PREVENTION AND TREATMENT OF PROTEIN KINASE RELATED DISEASES

Similar Documents

Publication Publication Date Title
CN105669676B (zh) 制备jak抑制剂及相关中间化合物的方法
EP2315521B1 (en) Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine h 4 receptor
MD4800C1 (ro) Compuşi de aminopirimidinil ca inhibitori de JAK
JP2025521545A (ja) 脊髄小脳失調症３型を処置するための化合物
WO2016024185A1 (en) Pyrrolo[2,3-d]pyrimidine derivatives useful for inhibiting janus kinase
MD3419978T2 (ro) Derivaţi de pirazolo[1,5-a]pirazin-4-il
JP2013503191A (ja) ヤヌスキナーゼインヒビターとしての複素環式化合物
JP2024525150A5 (https=)
US11273168B2 (en) Methods of treating anxiety by administering a substituted quinolone
RS65308B1 (sr) Biciklična ketonska jedinjenja i postupci za njihovu upotrebu
KR102485731B1 (ko) Jak 효소 억제제 및 이의 제조 방법과 용도
JP2020536915A (ja) Ｒｉｐ１キナーゼ阻害剤として使用するための二環式化合物
US20230159521A1 (en) 1h-pyrazolo[4,3-g]isoquinoline and 1h-pyrazolo[4,3-g]quinoline derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (aatd)
CN107667097B (zh) 3-乙基双环[3.2.0]庚-3-烯-6-酮的对映体的分离
JP2021100953A (ja) ピリミジニルシクロペンタン化合物の調製方法
JP2017515845A5 (https=)
WO2021084498A1 (en) Fluorinated quinoline, quinoxaline and benzo[b][1,4]oxazine derivatives as dihydroorotate dehydrogenase (dhodh) inhibitors for the treatment of cancer, autoimmune and inflammatory diseases
JP7688449B2 (ja) ピリジン縮合環系化合物とその製造方法、中間体、組成物及び使用
WO2023001247A1 (zh) 哒嗪酮类化合物
CN116425770A (zh) 作为Cdc7抑制剂的四并环类化合物
TWI878888B (zh) Ripk1抑制劑及使用方法
CN1630646A (zh) 旋光性吡咯衍生物及其制造方法
WO2013137479A1 (en) Decahydroquinoxaline derivatives and analogs thereof
RU2024100573A (ru) Замещенные пирроло[2,3-d]пиримидины, их получение и их терапевтическое применение
AU2022246900A8 (en) Processes for making bicyclic ketone compounds