JP2024524891A5 - - Google Patents

Info

Publication number
JP2024524891A5
JP2024524891A5 JP2023576235A JP2023576235A JP2024524891A5 JP 2024524891 A5 JP2024524891 A5 JP 2024524891A5 JP 2023576235 A JP2023576235 A JP 2023576235A JP 2023576235 A JP2023576235 A JP 2023576235A JP 2024524891 A5 JP2024524891 A5 JP 2024524891A5
Authority
JP
Japan
Prior art keywords
antibody
sequence
functional variant
heavy chain
cytokine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023576235A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024524891A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/067236 external-priority patent/WO2022268983A2/en
Publication of JP2024524891A publication Critical patent/JP2024524891A/ja
Publication of JP2024524891A5 publication Critical patent/JP2024524891A5/ja
Pending legal-status Critical Current

Links

JP2023576235A 2021-06-23 2022-06-23 インターロイキン-15に基づく免疫サイトカイン Pending JP2024524891A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP21181271 2021-06-23
EP21181271.4 2021-06-23
EP22163748.1 2022-03-23
EP22163748 2022-03-23
PCT/EP2022/067236 WO2022268983A2 (en) 2021-06-23 2022-06-23 Interleukin-15 based immunocytokines

Publications (2)

Publication Number Publication Date
JP2024524891A JP2024524891A (ja) 2024-07-09
JP2024524891A5 true JP2024524891A5 (enExample) 2025-06-10

Family

ID=82361370

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023576235A Pending JP2024524891A (ja) 2021-06-23 2022-06-23 インターロイキン-15に基づく免疫サイトカイン

Country Status (10)

Country Link
US (1) US20240294594A1 (enExample)
EP (1) EP4359428A2 (enExample)
JP (1) JP2024524891A (enExample)
KR (1) KR20240024242A (enExample)
AU (1) AU2022296794A1 (enExample)
BR (1) BR112023027312A2 (enExample)
CA (1) CA3221886A1 (enExample)
IL (1) IL309533A (enExample)
MX (1) MX2023015444A (enExample)
WO (1) WO2022268983A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3444271T (pt) 2013-08-08 2022-01-05 Inst Nat Sante Rech Med Modulocinas baseadas em il-15 e no domínio sushi de il-15ralfa
US20230030674A1 (en) * 2019-12-06 2023-02-02 Sotio Biotech A.S. Humanized cldn18.2 antibodies
WO2025177263A1 (en) * 2024-02-25 2025-08-28 Biohaven Therapeutics Ltd. Myostatin-binding proteins

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI259837B (en) 1998-05-11 2006-08-11 Eidgenossische Tech Hochscule Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis
US20100082438A1 (en) 2008-10-01 2010-04-01 Ronnie Jack Garmon Methods and systems for customer performance scoring
US20110318302A1 (en) 2009-01-07 2011-12-29 Kathrin Schwager Cancer Treatment
JP6594855B2 (ja) * 2013-03-15 2019-10-23 ゼンコア インコーポレイテッド ヘテロ二量体タンパク質
WO2014174105A1 (en) 2013-04-25 2014-10-30 Philochem Ag Antibody-drug conjugates
AU2016365114A1 (en) 2015-11-30 2018-05-17 Abbvie Biotherapeutics Inc. Anti-huLRRC15 antibody drug conjugates and methods for their use
MY203000A (en) * 2016-10-14 2024-06-01 Xencor Inc Il15/il15r� heterodimeric fc-fusion proteins
MY201482A (en) 2017-04-03 2024-02-26 Hoffmann La Roche Immunoconjugates of an anti-pd-1 antibody with a mutant il-2 or with il-15
AU2019228381B2 (en) 2018-02-28 2021-12-16 Pfizer Inc. IL-15 variants and uses thereof
CA3090407A1 (en) * 2018-03-01 2019-09-06 Glycotope Gmbh Fusion protein constructs comprising an anti-muc1 antibody and il-15
MA52289A (fr) * 2018-04-18 2021-02-24 Xencor Inc Protéines de fusion fc hétérodimères il-15/il-15ra et leurs utilisations
AU2019359475A1 (en) * 2018-10-12 2021-05-20 Xencor, Inc. PD-1 targeted IL-15/IL-15Ralpha Fc fusion proteins and uses in combination therapies thereof
US11738050B2 (en) 2019-02-01 2023-08-29 Regents Of The University Of Minnesota Compounds binding to fibroblast activation protein alpha
CA3153542A1 (en) * 2019-09-25 2021-04-01 Leto Laboratories Co., Ltd Recombinant interleukin-15 analog

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