JP2024523332A5 - - Google Patents

Info

Publication number
JP2024523332A5
JP2024523332A5 JP2023577490A JP2023577490A JP2024523332A5 JP 2024523332 A5 JP2024523332 A5 JP 2024523332A5 JP 2023577490 A JP2023577490 A JP 2023577490A JP 2023577490 A JP2023577490 A JP 2023577490A JP 2024523332 A5 JP2024523332 A5 JP 2024523332A5
Authority
JP
Japan
Prior art keywords
cells
concentration
cell population
medium containing
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577490A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024523332A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/055504 external-priority patent/WO2022264033A1/en
Publication of JP2024523332A publication Critical patent/JP2024523332A/ja
Publication of JP2024523332A5 publication Critical patent/JP2024523332A5/ja
Pending legal-status Critical Current

Links

JP2023577490A 2021-06-15 2022-06-14 多能性幹細胞からナチュラルキラー細胞を産生するための方法 Pending JP2024523332A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163210683P 2021-06-15 2021-06-15
US63/210,683 2021-06-15
PCT/IB2022/055504 WO2022264033A1 (en) 2021-06-15 2022-06-14 Method for producing natural killer cells from pluripotent stem cells

Publications (2)

Publication Number Publication Date
JP2024523332A JP2024523332A (ja) 2024-06-28
JP2024523332A5 true JP2024523332A5 (enExample) 2025-06-19

Family

ID=82656646

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577490A Pending JP2024523332A (ja) 2021-06-15 2022-06-14 多能性幹細胞からナチュラルキラー細胞を産生するための方法

Country Status (13)

Country Link
US (1) US20240108656A1 (enExample)
EP (1) EP4355861A1 (enExample)
JP (1) JP2024523332A (enExample)
KR (1) KR20240021878A (enExample)
CN (1) CN117813374A (enExample)
AR (1) AR126145A1 (enExample)
AU (1) AU2022292988A1 (enExample)
BR (1) BR112023026141A2 (enExample)
CA (1) CA3222770A1 (enExample)
CO (1) CO2023018654A2 (enExample)
MX (1) MX2023014979A (enExample)
TW (1) TW202317755A (enExample)
WO (1) WO2022264033A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025188853A1 (en) * 2024-03-05 2025-09-12 R.P. Scherer Technologies, Llc Method of differentiation of pluripotent stem cells to natural killer cells

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797368A (en) 1985-03-15 1989-01-10 The United States Of America As Represented By The Department Of Health And Human Services Adeno-associated virus as eukaryotic expression vector
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US6013516A (en) 1995-10-06 2000-01-11 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
US5928906A (en) 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
US5994136A (en) 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
US9453219B2 (en) 2003-05-15 2016-09-27 Mello Biotech Taiwan Co., Ltd. Cosmetic designs and products using intronic RNA
CN101864392B (zh) 2005-12-13 2016-03-23 国立大学法人京都大学 核重新编程因子
EP3399025B1 (en) 2007-03-23 2025-05-07 Wisconsin Alumni Research Foundation Somatic cell reprogramming
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
EP2198011B1 (en) 2007-08-31 2016-06-08 Whitehead Institute for Biomedical Research Wnt pathway stimulation in reprogramming somatic cells
AU2008297024B2 (en) 2007-10-31 2014-08-28 Kyoto University Nuclear reprogramming method
JP5558097B2 (ja) 2007-12-10 2014-07-23 国立大学法人京都大学 効率的な核初期化方法
CA2709566A1 (en) 2007-12-17 2009-06-25 Gliamed, Inc. Stem-like cells and method for reprogramming adult mammalian somatic cells
WO2009091659A2 (en) 2008-01-16 2009-07-23 Shi-Lung Lin Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant rna agents
EP2250252A2 (en) 2008-02-11 2010-11-17 Cambridge Enterprise Limited Improved reprogramming of mammalian cells, and the cells obtained
EP2090649A1 (en) 2008-02-13 2009-08-19 Fondazione Telethon Method for reprogramming differentiated cells
US20110014164A1 (en) 2008-02-15 2011-01-20 President And Fellows Of Harvard College Efficient induction of pluripotent stem cells using small molecule compounds
JP5951254B2 (ja) 2008-03-17 2016-07-13 ザ スクリプス リサーチ インスティテュート 人工多能性幹細胞を作製するための化学的手法と遺伝的手法の組み合わせ法
WO2009114949A1 (en) 2008-03-20 2009-09-24 UNIVERSITé LAVAL Methods for deprogramming somatic cells and uses thereof
EP2276838A4 (en) 2008-04-07 2012-02-01 Nupotential Inc RE-PROGRAMMING A CELL BY INDUCING A PLURIPOTENTIC GENE THROUGH RNA INTERFERENCE
KR101606943B1 (ko) 2008-06-27 2016-03-28 고쿠리츠 다이가쿠 호진 교토 다이가쿠 유도된 다능성 줄기 세포의 효율적인 확립 방법
US9453204B2 (en) 2008-07-14 2016-09-27 Oklahoma Medical Research Foundation Production of pluripotent cells through inhibition of bright/ARID3a function
WO2010147612A1 (en) 2009-06-18 2010-12-23 Lixte Biotechnology, Inc. Methods of modulating cell regulation by inhibiting p53
WO2010033906A2 (en) 2008-09-19 2010-03-25 President And Fellows Of Harvard College Efficient induction of pluripotent stem cells using small molecule compounds
WO2010033920A2 (en) 2008-09-19 2010-03-25 Whitehead Institute For Biomedical Research Compositions and methods for enhancing cell reprogramming
WO2010042800A1 (en) 2008-10-10 2010-04-15 Nevada Cancer Institute Methods of reprogramming somatic cells and methods of use for such cells
WO2010050626A1 (en) 2008-10-30 2010-05-06 Kyoto University Method for producing induced pluripotent stem cells
WO2010056831A2 (en) 2008-11-12 2010-05-20 Nupotential, Inc. Reprogramming a cell by inducing a pluripotent gene through use of an hdac modulator
EP2376626A4 (en) 2008-12-13 2012-10-17 Dna Microarray MICRO-ENVIRONMENTAL NICHE ASSAY FOR SCREENING OF INDUCED PLURIPOTENT STEM CELLS (CIPS)
CN102388136B (zh) 2009-02-27 2014-10-01 国立大学法人京都大学 新颖的核重编程序物质
US20120122212A1 (en) 2009-03-06 2012-05-17 Marica Grskovic Tgf-beta pathway inhibitors for enhancement of cellular reprogramming of human cells
WO2010111422A2 (en) 2009-03-25 2010-09-30 The Salk Institute For Biological Studies Induced pluripotent stem cell generation using two factors and p53 inactivation
WO2010111409A2 (en) 2009-03-25 2010-09-30 The Salk Institute For Biological Studies Pluripotent stem cells
US8852940B2 (en) 2009-04-01 2014-10-07 The Regents Of The University Of California Embryonic stem cell specific microRNAs promote induced pluripotency
WO2010124290A2 (en) 2009-04-24 2010-10-28 Whitehead Institute For Biomedical Research Compositions and methods for deriving or culturing pluripotent cells
WO2010147395A2 (en) 2009-06-16 2010-12-23 Korea Research Institute Of Bioscience And Biotechnology Medium composition comprising neuropeptide y for the generation, maintenance, prologned undifferentiated growth of pluripotent stem cells and method of culturing pluripotent stem cell using the same
TWI654206B (zh) 2013-03-16 2019-03-21 諾華公司 使用人類化抗－ｃｄ１９嵌合抗原受體治療癌症
WO2016123100A1 (en) * 2015-01-26 2016-08-04 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
WO2017078807A1 (en) * 2015-11-04 2017-05-11 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
AU2018254442B2 (en) * 2017-04-18 2024-03-28 FUJIFILM Cellular Dynamics, Inc. Antigen-specific immune effector cells

Similar Documents

Publication Publication Date Title
JP2023516632A5 (enExample)
CN111235105B (zh) 一种从人多能干细胞分化为自然杀伤细胞的方法及应用
Bagley et al. Extended culture of multipotent hematopoietic progenitors without cytokine augmentation in a novel three-dimensional device
Yamaguchi et al. Serum-free coculture system for ex vivo expansion of human cord blood primitive progenitors and SCID mouse-reconstituting cells using human bone marrow primary stromal cells
Douay Experimental culture conditions are critical for ex vivo expansion of hematopoietic cells
US7790458B2 (en) Material and methods for the growth of hematopoietic stem cells
US9260696B2 (en) Method for developing natural killer cells from stem cells
Flores-Guzmán et al. Concise review: ex vivo expansion of cord blood-derived hematopoietic stem and progenitor cells: basic principles, experimental approaches, and impact in regenerative medicine
Ehring et al. Expansion of HPCs from cord blood in a novel 3D matrix
Flores-Guzmán et al. In vitro proliferation, expansion, and differentiation of a CD34+ cell-enriched hematopoietic cell population from human umbilical cord blood in response to recombinant cytokines
Mehta et al. Novel techniques for ex vivo expansion of cord blood: clinical trials
EP2079832A2 (en) Isolation and purification of hematopoietic stem cells from post-liposuction lipoaspirates
JP2002532087A (ja) 初期のｃｄ３４＋ｃｄ３８−骨髄幹細胞の増大のためのヒト脳内皮細胞及び増殖培地並びに方法
CN117050941B (zh) 一种制备自然杀伤细胞的方法
Flippe et al. Rapid and reproducible differentiation of hematopoietic and T cell progenitors from pluripotent stem cells
Kim et al. Ex Vivo Expansion of Human Umbilical Cord Blood CD34+ Cells in a Collagen Bead—Containing 3-Dimensional Culture System
CN114621920A (zh) 一种由造血干祖细胞向nk细胞分化的方法及培养基
CN117683713A (zh) 利用人多潜能干细胞体外制备t淋巴细胞和nk细胞
Alcorn et al. Ex vivo expansion of haemopoietic progenitor cells
Kita et al. Cord blood‐derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion
CN114402065A (zh) 低密度细胞培养
Barria et al. Maintenance and self-renewal of long-term reconstituting hematopoietic stem cells supported by amniotic fluid
Kawai et al. Feeder-free generation of CD4 single-positive helper T cells from human iPSCs via stage-specific modulation of Notch and TCR Signaling
RU2023133748A (ru) Способ получения естественных клеток-киллеров из плюрипотентных стволовых клеток
Ziegler et al. Expansion of stem and progenitor cells