JP2024522718A5 - - Google Patents

Info

Publication number
JP2024522718A5
JP2024522718A5 JP2023577349A JP2023577349A JP2024522718A5 JP 2024522718 A5 JP2024522718 A5 JP 2024522718A5 JP 2023577349 A JP2023577349 A JP 2023577349A JP 2023577349 A JP2023577349 A JP 2023577349A JP 2024522718 A5 JP2024522718 A5 JP 2024522718A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound according
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577349A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024522718A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033523 external-priority patent/WO2022266162A1/en
Publication of JP2024522718A publication Critical patent/JP2024522718A/ja
Publication of JP2024522718A5 publication Critical patent/JP2024522718A5/ja
Pending legal-status Critical Current

Links

JP2023577349A 2021-06-16 2022-06-15 神経変性疾患の治療のための、カルボン酸基を含むアゼチジニル化合物 Pending JP2024522718A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163211313P 2021-06-16 2021-06-16
US63/211,313 2021-06-16
PCT/US2022/033523 WO2022266162A1 (en) 2021-06-16 2022-06-15 Azetidinyl compounds comprising a carboxylic acid group for the treatment of neurodegenerative diseases

Publications (2)

Publication Number Publication Date
JP2024522718A JP2024522718A (ja) 2024-06-21
JP2024522718A5 true JP2024522718A5 (enExample) 2025-06-23

Family

ID=82595041

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577349A Pending JP2024522718A (ja) 2021-06-16 2022-06-15 神経変性疾患の治療のための、カルボン酸基を含むアゼチジニル化合物

Country Status (13)

Country Link
US (2) US11919879B2 (enExample)
EP (1) EP4355729A1 (enExample)
JP (1) JP2024522718A (enExample)
KR (1) KR20240021883A (enExample)
CN (1) CN117500785A (enExample)
AR (1) AR126159A1 (enExample)
AU (1) AU2022291768A1 (enExample)
BR (1) BR112023023420A2 (enExample)
CA (1) CA3217423A1 (enExample)
IL (1) IL308122A (enExample)
MX (1) MX2023014197A (enExample)
TW (1) TW202317534A (enExample)
WO (1) WO2022266162A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3217423A1 (en) * 2021-06-16 2022-12-22 Jeffrey M. Schkeryantz Azetidinyl compounds comprising a carboxylic acid group for the treatment of neurodegenerative diseases
KR20250114133A (ko) * 2022-12-16 2025-07-28 셀진 코포레이션 S1p5의 조정제로서의 헤테로시클릭 화합물
EP4735422A1 (en) 2023-06-30 2026-05-06 Sanofi Substituted cyclic compounds and methods of treating phenylketonuria and other amino acidurias
WO2026008750A1 (en) 2024-07-05 2026-01-08 Syngenta Crop Protection Ag Novel carboxamide compounds

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO167087C (no) 1985-10-25 1991-10-02 Secr Defence Brit Fremgangsmaate for fremstilling av en nitratester.
US5561227A (en) 1991-07-23 1996-10-01 Schering Corporation Process for the stereospecific synthesis of azetidinones
LT3300B (en) 1992-12-23 1995-06-26 Schering Corp Combination of a cholesterol biosynhtesis inhibitor and a beta- lactam cholesterol absorbtion inhibitor
CA2228647A1 (en) 1995-09-01 1997-03-13 Pharmacia & Upjohn Company Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings
WO2000005214A2 (en) 1998-07-24 2000-02-03 Pfizer Inc. Isoquinolines as urokinase inhibitors
ATE439131T1 (de) 2001-08-30 2009-08-15 Chemocentryx Inc Bicyclische verbindungen als hemmer der chemokin- bindung an us28
ATE452879T1 (de) 2002-07-12 2010-01-15 Sanofi Aventis Deutschland Heterozyklisch substituierte benzoylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JP4516430B2 (ja) 2002-12-20 2010-08-04 メルク・シャープ・エンド・ドーム・コーポレイション 1−(アミノ)インダン並びに(1,2−ジヒドロ−3−アミノ)−ベンゾフラン、ベンゾチオフェン及びインドール
JP4660199B2 (ja) 2002-12-23 2011-03-30 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 置換1−ピペリジン−4−イル−4−アゼチジン−3−イル−ピペラジン誘導体およびそれらのニューロキニン拮抗薬としての使用
GB0510204D0 (en) 2005-05-19 2005-06-22 Chroma Therapeutics Ltd Enzyme inhibitors
US7790707B2 (en) * 2006-03-21 2010-09-07 Epix Pharmaceuticals Inc. S1P receptor modulating compounds and use thereof
JP5043120B2 (ja) 2006-10-30 2012-10-10 クロマ セラピューティクス リミテッド ヒストンデアセチラーゼの阻害剤としてのヒドロキサメート
US20090137549A1 (en) 2006-11-09 2009-05-28 Paul John Edward Novel compounds useful for the treatment of degenerative & inflamatory diseases
WO2010056788A1 (en) 2008-11-17 2010-05-20 Merck Sharp & Dohme Corp. Anti-hypercholesterolemic compounds
CN102388048B (zh) 2009-02-10 2014-07-30 阿斯利康(瑞典)有限公司 三唑并[4,3-b]哒嗪衍生物及其用于前列腺癌的用途
WO2011036889A1 (ja) 2009-09-25 2011-03-31 武田薬品工業株式会社 複素環化合物
GB201002563D0 (en) 2010-02-15 2010-03-31 Cambridge Entpr Ltd Compounds
NZ603876A (en) 2010-05-13 2015-02-27 Amgen Inc Nitrogen heterocyclic compounds useful as pde10 inhibitors
MX2012013128A (es) 2010-05-13 2013-03-20 Amgen Inc Compuestos heterociclicos de nitrogeno como inhibidores de la fosfodiesterasa 10.
WO2012082947A1 (en) 2010-12-16 2012-06-21 Irm Llc Compounds and compositions as tgr5 agonists
EP2545964A1 (en) 2011-07-13 2013-01-16 Phenex Pharmaceuticals AG Novel FXR (NR1H4) binding and activity modulating compounds
EP2855457A1 (en) 2012-05-09 2015-04-08 Zoetis Products LLC Azetidine derivatives as antiparasitic agents
AR092348A1 (es) 2012-07-11 2015-04-15 Hoffmann La Roche DERIVADOS DE ARIL-SULTAMO COMO MODULADORES DE RORc
BR112015010649A2 (pt) 2012-11-16 2017-07-11 Bristol Myers Squibb Co moduladores de gpr40 à base de pirrolidina
WO2015055771A1 (en) 2013-10-17 2015-04-23 AbbVie Deutschland GmbH & Co. KG Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
CA2934700A1 (en) 2014-01-06 2015-07-09 Rhizen Pharmaceuticals Sa Glutaminase inhibitors
FR3017867A1 (fr) * 2014-02-21 2015-08-28 Inventiva Nouveaux composes de type phenylazetidine carboxylate ou carboxamide
TR201809633T4 (tr) 2014-05-07 2018-07-23 Bristol Myers Squibb Co Diyabet gibi hastalıkların tedavisine yönelik pirolidin GPR40 modülatörleri.
EP3191453B1 (en) 2014-09-09 2019-10-23 Bristol-Myers Squibb Company Phenyl-(aza)cycloalkyl carboxylic acid gpr120 modulators
US11219625B2 (en) 2015-07-24 2022-01-11 Yale University Inhibitors of N-linked glycosylation and methods using same
CA3001666C (en) 2015-10-12 2021-03-30 Chong Kun Dang Pharmaceutical Corp. Oxadiazole amine derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same
ES2975689T3 (es) * 2016-01-29 2024-07-11 Ono Pharmaceutical Co Derivado de tetrahidronaftaleno
PT3426243T (pt) 2016-03-09 2021-08-19 Raze Therapeutics Inc Inibidores de 3-fosfoglicerato desidrogenase e utilizações dos mesmos
WO2017205425A1 (en) 2016-05-24 2017-11-30 President And Fellows Of Harvard College Compounds for organic light emitting diode materials
BR112018075734A2 (pt) 2016-06-13 2019-04-02 Gilead Sciences, Inc. composto, composição farmacêutica, método para tratar um paciente com uma doença ou condição mediada pelo menos em parte por fxr, e, uso de um composto.
CA3252823A1 (en) 2016-06-13 2025-02-25 Gilead Sciences, Inc. Substituted tert-butyl-3-(2-chloro-phenyl)-3-hydroxyazetidine-1-carboxylate compounds
WO2018106818A1 (en) 2016-12-07 2018-06-14 Kura Oncology, Inc. Methods of promoting beta cell proliferation
AR110988A1 (es) 2017-02-21 2019-05-22 Sanofi Sa Compuestos de azetidina como moduladores de gpr119 para el tratamiento de la diabetes, la obesidad, la dislipidemia y trastornos relacionados
JP7365332B2 (ja) 2017-08-07 2023-10-19 ジョイント・ストック・カンパニー “バイオキャド” Cdk8/19阻害薬としての新規ヘテロ環式化合物
JP7281469B2 (ja) 2018-01-19 2023-05-25 イドーシア ファーマシューティカルズ リミテッド C5a受容体調節剤
EP3837252B1 (en) 2018-08-16 2025-12-10 Boehringer Ingelheim International GmbH Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors
MX2021001857A (es) 2018-08-17 2021-10-13 Genentech Inc Star Metodos de diagnostico y terapeuticos para el tratamiento del cancer de mama.
JPWO2020071550A1 (ja) 2018-10-04 2021-09-24 京都薬品工業株式会社 Cdk8阻害剤およびその用途
US11179383B2 (en) 2018-10-30 2021-11-23 Gilead Sciences, Inc. Compounds for inhibition of α4β7 integrin
CN111484479B (zh) 2019-01-25 2023-06-13 四川科伦博泰生物医药股份有限公司 氮杂环化合物、包含其的药物组合物及其制备方法和用途
JP7669299B2 (ja) 2019-07-03 2025-04-28 エフ. ホフマン-ラ ロシュ アーゲー 複素環モノアシルグリセロールリパーゼ(magl)阻害剤
ES2983098T3 (es) * 2019-08-20 2024-10-22 Ono Pharmaceutical Co Sal y forma cristalina de un compuesto que tiene actividad agonista por el receptor de S1P5
CN112887914A (zh) * 2019-11-30 2021-06-01 深圳市海思半导体有限公司 终端间定位方法及装置
CN111704613B (zh) 2020-06-23 2021-07-06 中国人民解放军军事科学院军事医学研究院 咪唑类衍生物及其作为trpv4抑制剂的用途
US12624003B2 (en) 2020-12-23 2026-05-12 Celgene Corporation Carboxylic acid containing indanyl compounds for the treatment of neurodegenerative diseases
CA3217423A1 (en) * 2021-06-16 2022-12-22 Jeffrey M. Schkeryantz Azetidinyl compounds comprising a carboxylic acid group for the treatment of neurodegenerative diseases

Similar Documents

Publication Publication Date Title
JP2022185107A5 (enExample)
JP2019518766A5 (enExample)
JP2020502047A5 (enExample)
JP2010530881A5 (enExample)
JP2024512154A5 (enExample)
JP2018518537A5 (enExample)
JP2018505898A5 (enExample)
JP2012522759A5 (enExample)
JP2020527175A5 (enExample)
JP2020533352A5 (enExample)
JP2022533069A5 (enExample)
JP2019518050A5 (enExample)
RU2010107169A (ru) Фармацевтическая композиция, содержащая оптически активное соединение, обладающее активностью агониста рецептора тромбопоэтина, и промежуточное соединение для этого
JP2023511349A5 (enExample)
JP2013542267A5 (enExample)
JP2023535453A5 (enExample)
JP2021512913A5 (enExample)
JP2005539045A5 (enExample)
JP2020063289A5 (enExample)
JP2010522710A5 (enExample)
JP2003529602A5 (enExample)
JP2024546678A5 (enExample)
JP2025516719A5 (enExample)
JP2010535706A5 (enExample)
JP2013525490A5 (enExample)