JP2024522167A5 - - Google Patents

Info

Publication number
JP2024522167A5
JP2024522167A5 JP2023575549A JP2023575549A JP2024522167A5 JP 2024522167 A5 JP2024522167 A5 JP 2024522167A5 JP 2023575549 A JP2023575549 A JP 2023575549A JP 2023575549 A JP2023575549 A JP 2023575549A JP 2024522167 A5 JP2024522167 A5 JP 2024522167A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
sequence
antisense oligonucleotide
pnpla3
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023575549A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024522167A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/055292 external-priority patent/WO2022259145A1/en
Publication of JP2024522167A publication Critical patent/JP2024522167A/ja
Publication of JP2024522167A5 publication Critical patent/JP2024522167A5/ja
Withdrawn legal-status Critical Current

Links

JP2023575549A 2021-06-08 2022-06-07 肝疾患の処置のための併用療法 Withdrawn JP2024522167A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163208299P 2021-06-08 2021-06-08
US63/208,299 2021-06-08
PCT/IB2022/055292 WO2022259145A1 (en) 2021-06-08 2022-06-07 Combination therapies for treatment of liver diseases

Publications (2)

Publication Number Publication Date
JP2024522167A JP2024522167A (ja) 2024-06-11
JP2024522167A5 true JP2024522167A5 (enExample) 2025-06-13

Family

ID=82214216

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023575549A Withdrawn JP2024522167A (ja) 2021-06-08 2022-06-07 肝疾患の処置のための併用療法

Country Status (12)

Country Link
US (1) US20250122504A1 (enExample)
EP (1) EP4352223A1 (enExample)
JP (1) JP2024522167A (enExample)
KR (1) KR20240019796A (enExample)
CN (1) CN117441017A (enExample)
AU (1) AU2022289514A1 (enExample)
CA (1) CA3221482A1 (enExample)
IL (1) IL308974A (enExample)
MX (1) MX2023014723A (enExample)
TW (1) TW202313974A (enExample)
WO (1) WO2022259145A1 (enExample)
ZA (1) ZA202400228B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4724472A2 (en) * 2023-06-09 2026-04-15 Sun Pharmaceutical Industries Limited Glp-1/gip dual, glp-1/gcg dual and glp-1/gip/gcg triple receptor agonists
TW202539705A (zh) * 2024-04-03 2025-10-16 瑞典商阿斯特捷利康公司 Pnpla3表現之抑制劑的劑量依賴性投予

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3572982D1 (en) 1984-03-06 1989-10-19 Takeda Chemical Industries Ltd Chemically modified lymphokine and production thereof
EP0401384B1 (en) 1988-12-22 1996-03-13 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
US8563521B2 (en) 2007-06-21 2013-10-22 Technische Universitat Munchen Biological active proteins having increased in vivo and/or in vitro stability
TWI617574B (zh) 2012-12-11 2018-03-11 梅迪繆思有限公司 用於治療肥胖之升糖素與glp-1共促效劑
TWI869213B (zh) * 2018-09-19 2025-01-01 美商Ionis製藥公司 Pnpla3表現之調節劑
CN114728017B (zh) * 2019-10-14 2025-10-28 阿斯利康(瑞典)有限公司 Pnpla3表达的调节剂
CN115176007A (zh) * 2019-12-16 2022-10-11 阿尔尼拉姆医药品有限公司 含类PATATIN磷脂酶结构域3(PNPLA3)iRNA组合物及其使用方法

Similar Documents

Publication Publication Date Title
EP3472362B1 (en) Papd5 and papd7 inhibitors for treating an hepatitis b infection
JP5872162B2 (ja) アンドロゲン受容体を標的化するlnaアンタゴニスト
KR101789603B1 (ko) Tnf 수퍼패밀리 수용체에 대한 스플라이스 스위칭올리고머 및 염증성 질환 치료용 약제학적 조성물
JP2022048397A (ja) オリゴマーおよびオリゴマー・コンジュゲート
CN105264091B (zh) 用于调节tau表达的组合物和方法
JP2024503609A5 (enExample)
JP6043347B2 (ja) 線維芽細胞増殖因子受容体4の発現のアンチセンス調節
JP2009508527A5 (enExample)
JP2025512469A (ja) 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用
KR20250004771A (ko) 근긴장성 이영양증을 치료하기 위한 근육 표적화 복합체의 투여
JP2025512464A (ja) 筋緊張性ジストロフィーを処置するための筋標的化複合体および製剤
JP2022552249A5 (enExample)
TW202113079A (zh) 經修飾之間隙子寡核苷酸及其使用方法
EA018986B1 (ru) Соединения-антагонисты рнк для модуляции активности бета-катенина
JP2014533944A (ja) Smn2スプライシングの調節のための化合物
JP2024538859A5 (enExample)
JP2021502359A5 (enExample)
US20250122504A1 (en) Combinations with modulators of pnpla3 expression
US20200318113A1 (en) Polynucleotide conjugates and uses thereof
TW202543656A (zh) 靶向CIDEB之RNAi藥劑及相關方法
TW202517282A (zh) 用於抑制抑制素次單元βE(INHBE)之表現的RNAi劑、其醫藥組合物及使用方法
TW202345861A (zh) 經修飾之間隔體寡聚物及其使用方法
AU2011326034A1 (en) Compositions and methods for treating androgen receptor dependent disorders including cancers
JP2024525078A5 (enExample)
US20240150768A1 (en) Methods for the treatment of nash with advanced fibrosis and/or cirrhosis