|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
US5350674A
(en)
|
1992-09-04 |
1994-09-27 |
Becton, Dickinson And Company |
Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US5928906A
(en)
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
GB2325003B
(en)
|
1996-10-17 |
2000-05-10 |
Oxford Biomedica Ltd |
Rectroviral vectors
|
|
GB9720465D0
(en)
|
1997-09-25 |
1997-11-26 |
Oxford Biomedica Ltd |
Dual-virus vectors
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
ATE528405T1
(de)
|
1997-12-22 |
2011-10-15 |
Oxford Biomedica Ltd |
Auf dem virus der infektiösen pferdeanämie (eiav) basierende vektoren
|
|
GB9803351D0
(en)
|
1998-02-17 |
1998-04-15 |
Oxford Biomedica Ltd |
Anti-viral vectors
|
|
FR2777909B1
(fr)
|
1998-04-24 |
2002-08-02 |
Pasteur Institut |
Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex
|
|
GB0009760D0
(en)
|
2000-04-19 |
2000-06-07 |
Oxford Biomedica Ltd |
Method
|
|
US9085778B2
(en)
|
2006-05-03 |
2015-07-21 |
VL27, Inc. |
Exosome transfer of nucleic acids to cells
|
|
JP5878126B2
(ja)
|
2009-11-13 |
2016-03-08 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
工学操作された微小胞を用いての直接的なタンパク質の送達
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
US10421960B2
(en)
|
2011-09-16 |
2019-09-24 |
The Trustees Of The University Of Pennsylvania |
RNA engineered T cells for the treatment of cancer
|
|
WO2013045639A1
(en)
*
|
2011-09-29 |
2013-04-04 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
LENTIVIRAL VECTORS PSEUDOTYPED WITH MUTANT BaEV GLYCOPROTEINS
|
|
EP3971286A3
(en)
|
2012-03-26 |
2022-04-20 |
The Regents of the University of California |
Nipah virus envelope pseudotyped lentiviruses and methods of use
|
|
CA2930339A1
(en)
|
2012-11-13 |
2014-05-22 |
Jan Lotvall |
Delivery of therapeutic agent
|
|
EP2990416B1
(en)
|
2014-08-29 |
2018-06-20 |
GEMoaB Monoclonals GmbH |
Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
|
|
WO2016077639A2
(en)
|
2014-11-12 |
2016-05-19 |
VL27, Inc. |
Nanovesicular therapies
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
US11623950B2
(en)
*
|
2015-07-09 |
2023-04-11 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Lentiviral vector expressing membrane-anchored or secreted antibody
|
|
WO2017058753A1
(en)
|
2015-09-28 |
2017-04-06 |
Trustees Of Dartmouth College |
Chimeric antigen receptor, regulatory cells and methods of use
|
|
WO2017058850A1
(en)
|
2015-09-28 |
2017-04-06 |
Regents Of The University Of Minnesota |
Chimeric antigen receptor (car) t cells as therapeutic interventions for auto- and allo-immunity
|
|
WO2017068077A1
(en)
|
2015-10-20 |
2017-04-27 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods and products for genetic engineering
|
|
EP3383411B1
(en)
|
2015-11-30 |
2025-07-09 |
Sana Biotechnology, Inc. |
Sub-mitochondrial particles for use in treating metabolic conditions
|
|
SG10202008883SA
(en)
|
2016-03-15 |
2020-10-29 |
Codiak Biosciences Inc |
Therapeutic membrane vesicles
|
|
EP3235908A1
(en)
|
2016-04-21 |
2017-10-25 |
Ecole Normale Superieure De Lyon |
Methods for selectively modulating the activity of distinct subtypes of cells
|
|
ES3052812T3
(en)
|
2017-05-08 |
2026-01-14 |
Flagship Pioneering Innovations V Inc |
Compositions for facilitating membrane fusion and uses thereof
|
|
US20200248169A1
(en)
|
2017-06-26 |
2020-08-06 |
The Broad Institute, Inc. |
Crispr/cas-cytidine deaminase based compositions, systems, and methods for targeted nucleic acid editing
|
|
CA3064601A1
(en)
|
2017-06-26 |
2019-01-03 |
President And Fellows Of Harvard College |
Crispr/cas-adenine deaminase based compositions, systems, and methods for targeted nucleic acid editing
|
|
US20210187018A1
(en)
|
2017-12-07 |
2021-06-24 |
Flagship Pioneering Innovations V, Inc. |
Cytobiologics and therapeutic uses thereof
|
|
US20210071163A1
(en)
|
2017-12-22 |
2021-03-11 |
The Broad Institute, Inc. |
Cas12b systems, methods, and compositions for targeted rna base editing
|
|
WO2019126762A2
(en)
|
2017-12-22 |
2019-06-27 |
The Broad Institute, Inc. |
Cas12a systems, methods, and compositions for targeted rna base editing
|
|
WO2019126709A1
(en)
|
2017-12-22 |
2019-06-27 |
The Broad Institute, Inc. |
Cas12b systems, methods, and compositions for targeted dna base editing
|
|
WO2019157319A1
(en)
|
2018-02-12 |
2019-08-15 |
Flagship Pioneering Innovations V, Inc. |
Devices and methods for delivering material into a biological tissue or cell
|
|
SG11202007606QA
(en)
|
2018-02-17 |
2020-09-29 |
Flagship Pioneering Innovations V Inc |
Compositions and methods for membrane protein delivery
|
|
MX2020012295A
(es)
|
2018-05-15 |
2021-03-31 |
Flagship Pioneering Innovations V Inc |
Composiciones de fusosoma y usos de estas.
|
|
WO2020014209A1
(en)
|
2018-07-09 |
2020-01-16 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions and uses thereof
|
|
EP3850088A4
(en)
|
2018-09-07 |
2023-07-19 |
Beam Therapeutics, Inc. |
Compositions and methods for improving base editing
|
|
WO2020102503A2
(en)
|
2018-11-14 |
2020-05-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for t cell delivery
|
|
AU2019378036B2
(en)
|
2018-11-14 |
2026-05-07 |
Flagship Pioneering Innovations V, Inc |
Compositions and methods for compartment-specific cargo delivery
|
|
CA3120082A1
(en)
|
2018-11-14 |
2020-05-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for cns delivery
|
|
WO2020102485A1
(en)
|
2018-11-14 |
2020-05-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for hematopoietic stem cell delivery
|
|
WO2020181202A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
A:t to t:a base editing through adenine deamination and oxidation
|
|
WO2020181195A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenine excision
|
|
WO2020181193A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenosine methylation
|
|
WO2020181178A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through thymine alkylation
|
|
EP3942043A2
(en)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
EP4100519A2
(en)
|
2020-02-05 |
2022-12-14 |
The Broad Institute, Inc. |
Adenine base editors and uses thereof
|
|
BR112022022603A2
(pt)
|
2020-05-08 |
2023-01-17 |
Broad Inst Inc |
Métodos e composições para edição simultânea de ambas as fitas de sequência alvo de nucleotídeos de fita dupla
|
|
JP2023543803A
(ja)
|
2020-09-24 |
2023-10-18 |
ザ ブロード インスティテュート,インコーポレーテッド |
プライム編集ガイドrna、その組成物、及びその使用方法
|