|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
US5350674A
(en)
|
1992-09-04 |
1994-09-27 |
Becton, Dickinson And Company |
Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US5928906A
(en)
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
WO1999032646A1
(en)
|
1997-12-22 |
1999-07-01 |
Oxford Biomedica (Uk) Limited |
Equine infectious anaemia virus (eiav) based
|
|
PT904392E
(pt)
|
1996-10-17 |
2001-06-29 |
Oxford Biomedica Ltd |
Vectores retrovirais
|
|
GB9720465D0
(en)
|
1997-09-25 |
1997-11-26 |
Oxford Biomedica Ltd |
Dual-virus vectors
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
GB9803351D0
(en)
|
1998-02-17 |
1998-04-15 |
Oxford Biomedica Ltd |
Anti-viral vectors
|
|
FR2777909B1
(fr)
|
1998-04-24 |
2002-08-02 |
Pasteur Institut |
Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex
|
|
GB0009760D0
(en)
|
2000-04-19 |
2000-06-07 |
Oxford Biomedica Ltd |
Method
|
|
US9085778B2
(en)
|
2006-05-03 |
2015-07-21 |
VL27, Inc. |
Exosome transfer of nucleic acids to cells
|
|
WO2011058052A1
(en)
|
2009-11-13 |
2011-05-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Direct protein delivery with engineered microvesicles
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
KR20140060541A
(ko)
|
2011-09-16 |
2014-05-20 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
암을 치료하기 위한 rna 조작된 t 세포
|
|
US9249426B2
(en)
*
|
2011-09-29 |
2016-02-02 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Lentiviral vectors pseudotyped with mutant BaEV glycoproteins
|
|
WO2013148327A1
(en)
|
2012-03-26 |
2013-10-03 |
The Regents Of The University Of California |
Nipah virus envelope psuedotyped lentiviruses and methods of their use
|
|
EP3415627A1
(en)
|
2012-11-13 |
2018-12-19 |
Codiak BioSciences, Inc. |
Delivery of therapeutic agent
|
|
ES2688035T3
(es)
|
2014-08-29 |
2018-10-30 |
Gemoab Monoclonals Gmbh |
Receptor de antígeno universal que expresa células inmunes para direccionamiento de antígenos múltiples diversos, procedimiento para fabricación del mismo y utilización del mismo para tratamiento de cáncer, infecciones y enfermedades autoinmunes
|
|
WO2016077639A2
(en)
|
2014-11-12 |
2016-05-19 |
VL27, Inc. |
Nanovesicular therapies
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
WO2017005923A1
(en)
*
|
2015-07-09 |
2017-01-12 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Lentiviral vector expressing membrane-anchored or secreted antibody
|
|
US20180291080A1
(en)
|
2015-09-28 |
2018-10-11 |
Trustees Of Dartmouth College |
Chimeric antigen receptor, regulatory cells and methods of use
|
|
EP3858388B1
(en)
|
2015-09-28 |
2024-07-03 |
Regents of the University of Minnesota |
Chimeric antigen receptor (car) t cells as therapeutic interventions for gvhd
|
|
JP7059179B2
(ja)
|
2015-10-20 |
2022-04-25 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
遺伝子操作のための方法及び製品
|
|
US20170151287A1
(en)
|
2015-11-30 |
2017-06-01 |
Flagship Ventures Management, Inc. |
Methods and compositions of chondrisomes
|
|
SG10202008883SA
(en)
|
2016-03-15 |
2020-10-29 |
Codiak Biosciences Inc |
Therapeutic membrane vesicles
|
|
US11325948B2
(en)
*
|
2016-03-19 |
2022-05-10 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
|
|
EP3235908A1
(en)
|
2016-04-21 |
2017-10-25 |
Ecole Normale Superieure De Lyon |
Methods for selectively modulating the activity of distinct subtypes of cells
|
|
US11576872B2
(en)
|
2017-05-08 |
2023-02-14 |
Flagship Pioneering Innovations V, Inc. |
Compositions for facilitating membrane fusion and uses thereof
|
|
CN111328290A
(zh)
|
2017-06-26 |
2020-06-23 |
博德研究所 |
用于靶向核酸编辑的基于crispr/cas-腺嘌呤脱氨酶的组合物、系统和方法
|
|
WO2019005886A1
(en)
|
2017-06-26 |
2019-01-03 |
The Broad Institute, Inc. |
CRISPR / CAS-CYTIDINE DEAMINASE COMPOSITIONS, SYSTEMS AND METHODS FOR TARGETED EDITING OF NUCLEIC ACIDS
|
|
EP3720502A4
(en)
|
2017-12-07 |
2022-01-19 |
Flagship Pioneering Innovations V, Inc. |
CYTOBIOLOGICS AND THERAPEUTIC USES THEREOF
|
|
EP3728576A4
(en)
|
2017-12-22 |
2021-11-24 |
The Broad Institute, Inc. |
CAS12B SYSTEMS, METHODS AND COMPOSITIONS FOR SPECIFIC EDITING OF RNA BASES
|
|
WO2019126762A2
(en)
|
2017-12-22 |
2019-06-27 |
The Broad Institute, Inc. |
Cas12a systems, methods, and compositions for targeted rna base editing
|
|
US20230193242A1
(en)
|
2017-12-22 |
2023-06-22 |
The Broad Institute, Inc. |
Cas12b systems, methods, and compositions for targeted dna base editing
|
|
WO2019157319A1
(en)
|
2018-02-12 |
2019-08-15 |
Flagship Pioneering Innovations V, Inc. |
Devices and methods for delivering material into a biological tissue or cell
|
|
BR112020016570A2
(pt)
|
2018-02-17 |
2020-12-15 |
Flagship Pioneering Innovations V, Inc. |
Composições e métodos para liberação de proteína de membrana
|
|
CN112367973A
(zh)
|
2018-05-15 |
2021-02-12 |
旗舰先锋创新V股份有限公司 |
融合剂脂质体组合物和其用途
|
|
CA3105953A1
(en)
|
2018-07-09 |
2020-01-16 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions and uses thereof
|
|
EP3850088A4
(en)
|
2018-09-07 |
2023-07-19 |
Beam Therapeutics, Inc. |
Compositions and methods for improving base editing
|
|
US20230048166A1
(en)
|
2018-11-14 |
2023-02-16 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for hematopoietic stem cell delivery
|
|
EP3880179A2
(en)
|
2018-11-14 |
2021-09-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for cns delivery
|
|
KR20210131991A
(ko)
|
2018-11-14 |
2021-11-03 |
플래그쉽 파이어니어링 이노베이션스 브이, 인크. |
구획-특이적 카고 전달을 위한 조성물 및 방법
|
|
WO2020102503A2
(en)
|
2018-11-14 |
2020-05-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for t cell delivery
|
|
WO2020181193A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenosine methylation
|
|
WO2020181178A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through thymine alkylation
|
|
WO2020181202A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
A:t to t:a base editing through adenine deamination and oxidation
|
|
WO2020181195A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenine excision
|
|
WO2020191241A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
US20230235309A1
(en)
|
2020-02-05 |
2023-07-27 |
The Broad Institute, Inc. |
Adenine base editors and uses thereof
|
|
CA3177481A1
(en)
|
2020-05-08 |
2021-11-11 |
David R. Liu |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
|
CA3193099A1
(en)
|
2020-09-24 |
2022-03-31 |
David R. Liu |
Prime editing guide rnas, compositions thereof, and methods of using the same
|