JP2024521750A5 - - Google Patents
Info
- Publication number
- JP2024521750A5 JP2024521750A5 JP2023572544A JP2023572544A JP2024521750A5 JP 2024521750 A5 JP2024521750 A5 JP 2024521750A5 JP 2023572544 A JP2023572544 A JP 2023572544A JP 2023572544 A JP2023572544 A JP 2023572544A JP 2024521750 A5 JP2024521750 A5 JP 2024521750A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- base editor
- polynucleotide
- intron
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163194431P | 2021-05-28 | 2021-05-28 | |
| US63/194,431 | 2021-05-28 | ||
| PCT/US2022/031419 WO2022251687A2 (en) | 2021-05-28 | 2022-05-27 | Compositions and methods for the self-inactivation of base editors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024521750A JP2024521750A (ja) | 2024-06-04 |
| JP2024521750A5 true JP2024521750A5 (enExample) | 2025-06-03 |
Family
ID=84230360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572544A Pending JP2024521750A (ja) | 2021-05-28 | 2022-05-27 | 塩基エディターの自己不活性化のための組成物及び方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240132868A1 (enExample) |
| EP (1) | EP4346840A4 (enExample) |
| JP (1) | JP2024521750A (enExample) |
| KR (1) | KR20240012377A (enExample) |
| CN (1) | CN117729926A (enExample) |
| AU (1) | AU2022280952A1 (enExample) |
| CA (1) | CA3219628A1 (enExample) |
| WO (1) | WO2022251687A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118813611B (zh) * | 2023-04-19 | 2025-09-16 | 清华大学 | 一种基于rna核酶的dear核酸操纵系统及其应用 |
| AU2024384487A1 (en) * | 2023-11-20 | 2026-06-04 | Beam Therapeutics Inc. | Compositions and methods for altering complement activation |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9580727B1 (en) * | 2015-08-07 | 2017-02-28 | Caribou Biosciences, Inc. | Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides |
| WO2018027078A1 (en) * | 2016-08-03 | 2018-02-08 | President And Fellows Of Harard College | Adenosine nucleobase editors and uses thereof |
| LT3700570T (lt) * | 2017-10-23 | 2025-04-10 | Stoke Therapeutics, Inc. | Priešprasmiai oligomerai, skirti būklių ir ligų, pagrįstų nonsens kodono nulemta mrnr degradacija, gydymui |
| JP2021505159A (ja) * | 2017-12-06 | 2021-02-18 | ジェネレーション バイオ カンパニー | 修飾型閉端ｄｎａ（ｃｅｄｎａ）を使用する遺伝子編集 |
| KR102853088B1 (ko) * | 2018-05-11 | 2025-09-02 | 빔 테라퓨틱스, 인크. | 프로그래밍가능한 염기 편집기 시스템을 이용하여 단일염기다형성을 편집하는 방법 |
| KR102894715B1 (ko) * | 2018-08-03 | 2025-12-03 | 빔 테라퓨틱스, 인크. | 핵산 표적 서열을 변형시키기 위한 다중-이펙터 핵염기 편집기 및 이를 이용하는 방법 |
| KR20210055733A (ko) * | 2018-09-07 | 2021-05-17 | 빔 테라퓨틱스, 인크. | 핵염기 편집 시스템을 전달하기 위한 조성물 및 방법 |
| CN119913134A (zh) * | 2019-08-29 | 2025-05-02 | 比姆医疗股份有限公司 | 用于编辑突变以允许转录或表达的组合物和方法 |
| AU2020344547A1 (en) * | 2019-09-09 | 2022-03-24 | Beam Therapeutics Inc. | Novel nucleobase editors and methods of using same |
-
2022
- 2022-05-27 KR KR1020237039212A patent/KR20240012377A/ko active Pending
- 2022-05-27 JP JP2023572544A patent/JP2024521750A/ja active Pending
- 2022-05-27 CN CN202280036220.2A patent/CN117729926A/zh active Pending
- 2022-05-27 CA CA3219628A patent/CA3219628A1/en active Pending
- 2022-05-27 EP EP22812298.2A patent/EP4346840A4/en active Pending
- 2022-05-27 AU AU2022280952A patent/AU2022280952A1/en active Pending
- 2022-05-27 WO PCT/US2022/031419 patent/WO2022251687A2/en not_active Ceased
-
2023
- 2023-11-27 US US18/519,954 patent/US20240132868A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7486206B2 (ja) | 人工的に構築されたｒｎａ編集酵素による部位特異的ｒｎａ編集および関連使用 | |
| CN114634930B (zh) | 使用rna指导型内切核酸酶改善基因组工程特异性的组合物和方法 | |
| JP2022546608A5 (enExample) | ||
| JP2023517294A5 (enExample) | ||
| JP2022523719A (ja) | Ａａｖキャプシドの転写依存性定方向進化を使用するための方法 | |
| EP4640697A1 (en) | Complex and use thereof | |
| EP3943512A1 (en) | Fusion protein for enhancing gene editing and use thereof | |
| JP2024523394A5 (enExample) | ||
| CN112708605A (zh) | 一个Cas9蛋白拆分得到的蛋白组及其应用 | |
| WO2018126087A1 (en) | Gene editing method using virus | |
| JP2024529425A5 (enExample) | ||
| CN110885799A (zh) | 一种基于腺病毒的基因编辑方法 | |
| WO2024238321A1 (en) | Compositions and methods for targeted epigenetic modification | |
| CN117230043B (zh) | Cas13蛋白及其应用 | |
| CA2532460A1 (en) | Synthetic gene encoding human epidermal growth factor 2/neu antigen and uses thereof | |
| JP2023539631A (ja) | Ｄｕｘ４遺伝子を標的とした顔面肩甲上腕型筋ジストロフィーの治療方法 | |
| KR20250109196A (ko) | 유전자 발현 및 공동 형질감염을 위한 dna 오리가미 인코딩 | |
| JP2023507034A5 (enExample) | ||
| US20250019667A1 (en) | Adenoviral helper plasmid | |
| JP2025514304A (ja) | 遺伝子治療法のための組織特異的遺伝子外セーフハーバーの同定 | |
| JP2025510714A (ja) | 遺伝子編集用のｒｎａフレームワーク及び遺伝子編集方法 | |
| Herzog et al. | Problems and prospects in gene therapy for hemophilia | |
| CN113661247A (zh) | 细胞穿透转座酶 | |
| JP2024533396A5 (enExample) | ||
| KR20240136988A (ko) | 스트렙토코커스 피오게네스 유래 Cas9 변이체 |