JP2024520900A5 - - Google Patents

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Publication number
JP2024520900A5
JP2024520900A5 JP2023569788A JP2023569788A JP2024520900A5 JP 2024520900 A5 JP2024520900 A5 JP 2024520900A5 JP 2023569788 A JP2023569788 A JP 2023569788A JP 2023569788 A JP2023569788 A JP 2023569788A JP 2024520900 A5 JP2024520900 A5 JP 2024520900A5
Authority
JP
Japan
Prior art keywords
inhibitor
combination
cancer
leukemia
therapeutically effective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023569788A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024520900A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/029002 external-priority patent/WO2022241122A1/en
Publication of JP2024520900A publication Critical patent/JP2024520900A/ja
Publication of JP2024520900A5 publication Critical patent/JP2024520900A5/ja
Pending legal-status Critical Current

Links

JP2023569788A 2021-05-12 2022-05-12 癌の治療のための組合せ Pending JP2024520900A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163187753P 2021-05-12 2021-05-12
US63/187,753 2021-05-12
PCT/US2022/029002 WO2022241122A1 (en) 2021-05-12 2022-05-12 Combinations for treatment of cancer

Publications (2)

Publication Number Publication Date
JP2024520900A JP2024520900A (ja) 2024-05-27
JP2024520900A5 true JP2024520900A5 (https=) 2025-05-19

Family

ID=84028869

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023569788A Pending JP2024520900A (ja) 2021-05-12 2022-05-12 癌の治療のための組合せ

Country Status (8)

Country Link
US (1) US20240238291A1 (https=)
EP (1) EP4337329A4 (https=)
JP (1) JP2024520900A (https=)
KR (1) KR20240006625A (https=)
CN (1) CN117425495A (https=)
AU (1) AU2022271791A1 (https=)
CA (1) CA3214990A1 (https=)
WO (1) WO2022241122A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017214367A1 (en) 2016-06-10 2017-12-14 Vitae Pharmaceuticals, Inc. Inhibitors of the menin-mll interaction
TW202525813A (zh) 2019-12-19 2025-07-01 比利時商健生藥品公司 經取代之直鏈螺環接衍生物
EP4132932A4 (en) 2020-04-07 2024-04-17 Syndax Pharmaceuticals, Inc. COMBINATIONS OF MENIN INHIBITORS AND CYP3A4 INHIBITORS AND METHODS OF USE THEREOF
CN120529900A (zh) 2022-11-24 2025-08-22 奥莱松基因组股份有限公司 用于治疗癌症的LSD1抑制剂和Menin抑制剂的组合
EP4626426A1 (en) * 2022-11-30 2025-10-08 JANSSEN Pharmaceutica NV Combinations comprising a menin-mll inhibitor and at least one other therapeutic agent
WO2024114666A1 (en) * 2022-11-30 2024-06-06 Janssen Pharmaceutica Nv Combinations comprising a menin-mll inhibitor and a bcl-2 inhibitor
TW202517650A (zh) * 2023-07-17 2025-05-01 美商庫拉腫瘤技術股份有限公司 包含menin抑制劑之醫藥組合物
IL325861A (en) 2023-07-17 2026-03-01 Kura Oncology Inc Crystalline forms of menin inhibitor
WO2025082444A2 (en) * 2023-10-20 2025-04-24 Janssen Pharmaceutica Nv (r) -n-ethyl-5-fluoro-n-isopropyl-2- ( (5- (2- (6- ( (2-methoxyethyl) (methyl) amino) -2-methylhexan-3-yl) -2, 6-diazaspiro [3.4] octan-6-yl) -1, 2, 4-triazin-6-yl) oxy) benzamide, formulations and dosage regimens thereof, for use in treating cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10869868B2 (en) * 2016-01-26 2020-12-22 Memorial Sloan Kettering Cancer Center Targeting chromatin regulators inhibits leukemogenic gene expression in NPM1 mutant leukemia
JP6991585B2 (ja) * 2016-05-02 2022-01-12 ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン メニン阻害剤としてのピペリジン

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