JP2020505433A5 - - Google Patents

Download PDF

Info

Publication number
JP2020505433A5
JP2020505433A5 JP2019542191A JP2019542191A JP2020505433A5 JP 2020505433 A5 JP2020505433 A5 JP 2020505433A5 JP 2019542191 A JP2019542191 A JP 2019542191A JP 2019542191 A JP2019542191 A JP 2019542191A JP 2020505433 A5 JP2020505433 A5 JP 2020505433A5
Authority
JP
Japan
Prior art keywords
cancer
mpc
amount
bcl
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2019542191A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020505433A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/016361 external-priority patent/WO2018144680A1/en
Publication of JP2020505433A publication Critical patent/JP2020505433A/ja
Publication of JP2020505433A5 publication Critical patent/JP2020505433A5/ja
Withdrawn legal-status Critical Current

Links

JP2019542191A 2017-02-03 2018-02-01 Hsp90阻害剤を使用してがんを治療するための方法 Withdrawn JP2020505433A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762454113P 2017-02-03 2017-02-03
US62/454,113 2017-02-03
US201762563991P 2017-09-27 2017-09-27
US62/563,991 2017-09-27
US201762587886P 2017-11-17 2017-11-17
US62/587,886 2017-11-17
PCT/US2018/016361 WO2018144680A1 (en) 2017-02-03 2018-02-01 Methods for treating cancer using hsp90 inhibitors

Publications (2)

Publication Number Publication Date
JP2020505433A JP2020505433A (ja) 2020-02-20
JP2020505433A5 true JP2020505433A5 (https=) 2021-03-11

Family

ID=63038389

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019542191A Withdrawn JP2020505433A (ja) 2017-02-03 2018-02-01 Hsp90阻害剤を使用してがんを治療するための方法

Country Status (13)

Country Link
US (2) US10799508B2 (https=)
EP (1) EP3576794A1 (https=)
JP (1) JP2020505433A (https=)
KR (1) KR20190110128A (https=)
CN (1) CN110536702A (https=)
AU (1) AU2018215336A1 (https=)
BR (1) BR112019016024A2 (https=)
CA (1) CA3052594A1 (https=)
IL (1) IL268430A (https=)
MX (1) MX2019009227A (https=)
RU (1) RU2019127350A (https=)
TW (1) TW201840337A (https=)
WO (1) WO2018144680A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3576794A1 (en) 2017-02-03 2019-12-11 AI Therapeutics, Inc. Methods for treating cancer using hsp90 inhibitors
EP3687542A1 (en) * 2017-09-27 2020-08-05 AI Therapeutics, Inc. Therapeutic methods relating to hsp90 inhibitors
CA3118175A1 (en) * 2018-11-08 2020-05-14 Glaxosmithkline Intellectual Property Development Limited Combination of prmt5 inhibitors and bcl-2 inhibitors
CN113874016A (zh) 2019-01-29 2021-12-31 福宏治疗公司 化合物及其用途
MX2021015423A (es) * 2019-06-25 2022-01-24 Tarveda Therapeutics Inc Conjugados de union a hsp90 y terapias combinadas de los mismos.
WO2021022163A2 (en) 2019-07-31 2021-02-04 Foghorn Therapeutics Inc. Compounds and uses thereof
KR20220098755A (ko) 2019-11-05 2022-07-12 애브비 인코포레이티드 나비토클락스를 사용한 골수섬유증 및 mpn 관련 장애 치료에 사용하기 위한 투약 레지멘
US12528825B2 (en) 2020-01-29 2026-01-20 Foghorn Therapeutics Inc. Compounds and uses thereof
US20230100235A1 (en) * 2020-02-05 2023-03-30 Carna Biosciences, Inc. Anticancer agent composition
KR102683903B1 (ko) * 2020-09-16 2024-07-12 한국원자력의학원 아리피프라졸을 유효성분으로 함유하는 bcl2 저해제의 항암 효과 증진용 조성물
CN116615195A (zh) * 2020-09-17 2023-08-18 阿尔伯爱因斯坦医学院 使用bax激活剂的组合治疗
EP4213840A4 (en) * 2020-09-17 2024-10-16 Albert Einstein College of Medicine COMBINATION THERAPY USING A BAX-ACTIVATING AGENT
EP4413046A4 (en) * 2021-10-05 2025-11-26 Univ Texas PROCESSES AND COMPOSITIONS COMPRISING B7-H3 BONDING POLYPEPTIDES
CN114588269B (zh) * 2022-04-06 2023-06-27 宁波大学附属人民医院 Bcl-2抑制剂和HDAC抑制剂的组合物及其用途
WO2024006292A2 (en) * 2022-06-27 2024-01-04 Foghorn Therapeutics Inc. Methods of treating cancer
CN115957328A (zh) * 2022-07-13 2023-04-14 杭州百可生物科技有限公司 一种用于治疗白血病的药物组合物以及白血病的治疗方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011060253A2 (en) 2009-11-13 2011-05-19 Myrexis, Inc. Methods of treating diseases, pharmaceutical compositions, and pharmaceutical dosage forms
EP2533781B1 (en) * 2010-02-12 2016-11-16 Niiki Pharma Inc. Method for treating hematological cancers of myeloid origin
WO2012148550A1 (en) * 2011-02-25 2012-11-01 Myrexis, Inc. Prodrugs of therapeutic compounds
BR112013027448A2 (pt) * 2011-04-28 2020-09-01 Sloan-Kettering Institute For Cancer Research terapia de combinação com hsp90
EP3576794A1 (en) 2017-02-03 2019-12-11 AI Therapeutics, Inc. Methods for treating cancer using hsp90 inhibitors
EP3687542A1 (en) 2017-09-27 2020-08-05 AI Therapeutics, Inc. Therapeutic methods relating to hsp90 inhibitors

Similar Documents

Publication Publication Date Title
JP2020505433A5 (https=)
US20220088029A1 (en) Combination therapy of tetracyclic quinolone analogs for treating cancer
RU2757373C2 (ru) Комбинированная терапия противоопухолевым алкалоидом
EP3066101B1 (en) Combination therapy for cancer using bromodomain and extra-terminal (bet) protein inhibitors
US20170259081A1 (en) Methods for regulating cell mitosis by inhibiting serine/threonine phosphatase
US20100029683A1 (en) Methods for regulating cell mitosis by inhibiting serine/threonine phosphateses
CN110536702A (zh) 使用hsp90抑制剂治疗癌症的方法
JP2017530983A (ja) 相乗的オーリスタチン組合せ
WO2010081817A1 (en) Method for treating colorectal cancer
CN102753176B (zh) 含有cdc7抑制剂和抗癌药的治疗组合物
JP2017503842A (ja) 癌治療のためのアピリモド(apilimod)組成物
JP2018525358A (ja) アピリモドを用いる癌の処置方法
EP2435041A1 (en) Therapeutic combination comprising a plk1 inhibitor and an antineoplastic agent
CA2902144A1 (en) Methods and compositions for treating cancers having acquired resistance to prior chemotherapeutic and targeted drugs using carboxyamidotriazole orotate
JP2021501140A (ja) リンパ球悪性疾患を治療するための方法
CN113365610A (zh) 制备和递送比生群制剂的方法
EP3445366A1 (en) Method of treating liver cancer
WO2016032882A1 (en) Inhibition of mk2 in the treatment of cancer
JP7547360B2 (ja) Pkm2モジュレーターを含む組成物およびそれを使用する処置の方法
JP7479292B2 (ja) 組み合わせ医薬として用いられるezh1/2二重阻害剤を含有する医薬組成物
CN112043831A (zh) 用于联合治疗乳腺癌的喹啉类化合物
CN105744958A (zh) 新颖医药组成物及其用途
KR20260018865A (ko) Kras-의존성 암 치료용 파네실트랜스퍼라제 억제제
JP2020528418A (ja) BET阻害剤及びBcl−2阻害剤を用いた併用療法
TW201919645A (zh) 作為免疫調節劑的磷酸鉑(phosphaplatin)化合物及其治療用途