JP2024519397A5 - - Google Patents
Info
- Publication number
- JP2024519397A5 JP2024519397A5 JP2023573077A JP2023573077A JP2024519397A5 JP 2024519397 A5 JP2024519397 A5 JP 2024519397A5 JP 2023573077 A JP2023573077 A JP 2023573077A JP 2023573077 A JP2023573077 A JP 2023573077A JP 2024519397 A5 JP2024519397 A5 JP 2024519397A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion polypeptide
- trail
- cancer
- fusion
- fusion protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2021/096498 | 2021-05-27 | ||
| CN2021096498 | 2021-05-27 | ||
| PCT/CN2022/095472 WO2022247923A1 (en) | 2021-05-27 | 2022-05-27 | A super-trail molecule comprising two trail trimers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024519397A JP2024519397A (ja) | 2024-05-10 |
| JP2024519397A5 true JP2024519397A5 (enExample) | 2025-06-03 |
Family
ID=84228436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023573077A Pending JP2024519397A (ja) | 2021-05-27 | 2022-05-27 | ２つのｔｒａｉｌ三量体を含むスーパーｔｒａｉｌ分子 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240254193A1 (enExample) |
| EP (1) | EP4347665A4 (enExample) |
| JP (1) | JP2024519397A (enExample) |
| KR (1) | KR20240013766A (enExample) |
| CN (1) | CN117396520A (enExample) |
| AU (1) | AU2022280269A1 (enExample) |
| CA (1) | CA3220239A1 (enExample) |
| IL (1) | IL308618A (enExample) |
| WO (1) | WO2022247923A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120475984A (zh) * | 2023-01-05 | 2025-08-12 | 国家纳米科学中心 | Dna-trail复合物及其治疗肿瘤的用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19963859A1 (de) * | 1999-12-30 | 2001-07-12 | Apotech Res & Dev Ltd | Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen |
| EP1894940A1 (en) * | 2006-08-28 | 2008-03-05 | Apogenix GmbH | TNF superfamily fusion proteins |
| CN102898526A (zh) * | 2011-07-28 | 2013-01-30 | 山东先声麦得津生物制药有限公司 | 一种肿瘤坏死因子相关凋亡诱导配体融合蛋白及其制备和应用 |
| US20150038682A1 (en) * | 2013-08-02 | 2015-02-05 | Jn Biosciences Llc | Antibodies or fusion proteins multimerized via homomultimerizing peptide |
| PL3145530T3 (pl) * | 2014-04-21 | 2021-10-18 | D&D Pharmatech Inc. | Agonisty receptora trail w leczeniu chorób zwłóknieniowych |
| US10428149B2 (en) * | 2015-03-18 | 2019-10-01 | Universitat Stuttgart | Single-chain tumor necrosis factor (TNF) ligand family molecules, fusion proteins and derivatives thereof |
| WO2017194442A1 (en) * | 2016-05-11 | 2017-11-16 | F. Hoffmann-La Roche Ag | Antigen binding molecules comprising a tnf family ligand trimer and a tenascin binding moiety |
| WO2018183671A1 (en) * | 2017-03-29 | 2018-10-04 | Tdw Group | Protein conjugates |
-
2022
- 2022-05-27 KR KR1020237043997A patent/KR20240013766A/ko active Pending
- 2022-05-27 EP EP22810647.2A patent/EP4347665A4/en active Pending
- 2022-05-27 US US18/564,554 patent/US20240254193A1/en active Pending
- 2022-05-27 JP JP2023573077A patent/JP2024519397A/ja active Pending
- 2022-05-27 AU AU2022280269A patent/AU2022280269A1/en active Pending
- 2022-05-27 WO PCT/CN2022/095472 patent/WO2022247923A1/en not_active Ceased
- 2022-05-27 CA CA3220239A patent/CA3220239A1/en active Pending
- 2022-05-27 IL IL308618A patent/IL308618A/en unknown
- 2022-05-27 CN CN202280038107.8A patent/CN117396520A/zh active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7200138B2 (ja) | アルブミン結合ドメイン融合タンパク質 | |
| US8927693B2 (en) | Fibronectin based scaffold domain proteins that bind IL-23 | |
| JP7121496B2 (ja) | 癌治療で使用するためのペグ化インターロイキン－１０ | |
| CN100447244C (zh) | Baff受体(bcma),一种免疫调节剂 | |
| US12589134B2 (en) | Compositions and methods of use of interleukin-10 in combination with immune check-point pathway inhibitors | |
| US20100215655A1 (en) | Angiogenesis-inhibiting chimeric proteins and the use | |
| JP2007530021A (ja) | Ｔｎｆリガンドファミリーメンバーの組換えポリペプチドおよびその使用 | |
| US10618949B2 (en) | Method and compositions for producing disulfide-linked trimeric TNF family of cytokines and their use | |
| CA2898128A1 (en) | Factor 1 protein, factor 2 protein and inhibitors thereof for use in treating or preventing diseases | |
| KR20240095463A (ko) | 변형된 IgG1 Fc 도메인 및 그와의 항-CD40 도메인 항체 융합체 | |
| CA2963995A1 (en) | Methods of using interleukin-10 for treating diseases and disorders | |
| KR20080022539A (ko) | 키메라 단백질 | |
| JP4823060B2 (ja) | Ｔｗｅａｋ受容体のマルチマー化およびオリゴマー化可溶性断片に関する組成物および方法 | |
| US20210347842A1 (en) | Compositions and methods of use of il-10 agents in conjunction with chimeric antigen receptor cell therapy | |
| NZ501831A (en) | Trail binding protein (TRAIL-BP) showing significant homology to the extracellular domains of members of the tumour necrosis factor receptor (TNF-R) and is anchored to cell surface via glycosylphosphatidylinositol (GPI) linkage | |
| JP7221545B2 (ja) | ホスファチジルセリン標的化融合分子およびそれらの使用方法 | |
| JP2024519397A5 (enExample) | ||
| US20150183864A1 (en) | Fusion protein capable of binding vegf-a and tnf-alpha | |
| US10618970B2 (en) | Method of treating cancer with IL-10 and antibodies that induce ADCC | |
| US20050181994A1 (en) | Novel variants of CD40L protein | |
| WO2011122127A1 (ja) | 骨芽細胞増殖促進活性を有するペプチドおよびその利用 | |
| KR20240013766A (ko) | 2개의 trail 삼량체를 포함하는 수퍼-trail 분자 | |
| JP2024520569A (ja) | ｓＰＤ－１及びＩＬ－１５を有する二重特異性Ｆｃ融合タンパク質 | |
| HK40101761A (zh) | 包含两个trail三聚体的超trail分子 |