JP2024516613A5 - - Google Patents

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Publication number
JP2024516613A5
JP2024516613A5 JP2023564508A JP2023564508A JP2024516613A5 JP 2024516613 A5 JP2024516613 A5 JP 2024516613A5 JP 2023564508 A JP2023564508 A JP 2023564508A JP 2023564508 A JP2023564508 A JP 2023564508A JP 2024516613 A5 JP2024516613 A5 JP 2024516613A5
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JP
Japan
Prior art keywords
linker
cpmb
conjugate according
gal
fam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023564508A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024516613A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/088117 external-priority patent/WO2022222986A1/en
Publication of JP2024516613A publication Critical patent/JP2024516613A/ja
Publication of JP2024516613A5 publication Critical patent/JP2024516613A5/ja
Pending legal-status Critical Current

Links

JP2023564508A 2021-04-23 2022-04-21 肝臓細胞への薬物送達のための環状ペプチド-N-アセチルガラクトサミン(GalNAc)コンジュゲート Pending JP2024516613A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2021/089305 2021-04-23
CN2021089305 2021-04-23
PCT/CN2022/088117 WO2022222986A1 (en) 2021-04-23 2022-04-21 Cyclic peptide-n-acetylgalactosamine (galnac) conjugates for drug delivery to liver cells

Publications (2)

Publication Number Publication Date
JP2024516613A JP2024516613A (ja) 2024-04-16
JP2024516613A5 true JP2024516613A5 (enExample) 2025-04-25

Family

ID=83723528

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023564508A Pending JP2024516613A (ja) 2021-04-23 2022-04-21 肝臓細胞への薬物送達のための環状ペプチド-N-アセチルガラクトサミン(GalNAc)コンジュゲート

Country Status (9)

Country Link
US (1) US20240218023A1 (enExample)
EP (1) EP4326744A4 (enExample)
JP (1) JP2024516613A (enExample)
KR (1) KR20240044385A (enExample)
CN (1) CN117529490A (enExample)
AU (1) AU2022261265A1 (enExample)
IL (1) IL307882A (enExample)
WO (1) WO2022222986A1 (enExample)
ZA (1) ZA202309922B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024117938A1 (ru) * 2022-11-30 2024-06-06 Общество с ограниченной ответственностью "СИСТЕМА-БИОТЕХ" Способы получения биоконъюгатов для печень-специфической направленной модуляции протеома
WO2024152775A1 (zh) * 2023-01-17 2024-07-25 云合智药(苏州)生物科技有限公司 缀合物、配体单元及其用途
WO2025016294A1 (zh) * 2023-07-14 2025-01-23 云合智药(苏州)生物科技有限公司 用于抑制己酮糖激酶表达的RNAi剂及其应用
CN120040554B (zh) * 2025-04-25 2025-07-18 云合智药(苏州)生物科技有限公司 环肽类肝靶向化合物、药物组合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE350393T1 (de) * 2002-09-19 2007-01-15 Centre Nat Rech Scient Synthese und charakterisierung neuer systeme zum hinführen und zur vektorisierung von molekülen von therapeutischem interesse zu targetzellen
FR2959993B1 (fr) * 2010-05-17 2014-10-17 Commissariat Energie Atomique Nouveaux composes cyclodecapeptides et leurs applications
US8501930B2 (en) * 2010-12-17 2013-08-06 Arrowhead Madison Inc. Peptide-based in vivo siRNA delivery system
WO2019217682A1 (en) * 2018-05-09 2019-11-14 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues

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