JP2024513003A5 - - Google Patents
Info
- Publication number
- JP2024513003A5 JP2024513003A5 JP2023559849A JP2023559849A JP2024513003A5 JP 2024513003 A5 JP2024513003 A5 JP 2024513003A5 JP 2023559849 A JP2023559849 A JP 2023559849A JP 2023559849 A JP2023559849 A JP 2023559849A JP 2024513003 A5 JP2024513003 A5 JP 2024513003A5
- Authority
- JP
- Japan
- Prior art keywords
- csf1r
- modified
- nucleic acid
- recombinant nucleic
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163169578P | 2021-04-01 | 2021-04-01 | |
| US63/169,578 | 2021-04-01 | ||
| US202163236951P | 2021-08-25 | 2021-08-25 | |
| US63/236,951 | 2021-08-25 | ||
| PCT/US2022/023139 WO2022212897A1 (en) | 2021-04-01 | 2022-04-01 | Genetic modification of mammalian cells to confer resistance to csf1r antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024513003A JP2024513003A (ja) | 2024-03-21 |
| JP2024513003A5 true JP2024513003A5 (https=) | 2025-04-03 |
Family
ID=83456857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023559849A Pending JP2024513003A (ja) | 2021-04-01 | 2022-04-01 | Ｃｓｆ１ｒアンタゴニストに対する耐性を付与するための哺乳動物細胞の遺伝子改変 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US12421517B2 (https=) |
| EP (1) | EP4314003A4 (https=) |
| JP (1) | JP2024513003A (https=) |
| AU (1) | AU2022252407A1 (https=) |
| CA (1) | CA3215311A1 (https=) |
| DE (4) | DE112022000079T5 (https=) |
| GB (1) | GB2612467B (https=) |
| WO (1) | WO2022212897A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12612599B2 (en) | 2018-09-10 | 2026-04-28 | Savanna Biotherapeutics, Inc. | Compositions and methods for microglia replacement therapy |
| CA3215311A1 (en) | 2021-04-01 | 2022-10-06 | The Regents Of The University Of California | Genetic modification of mammalian cells to confer resistance to csf1r antagonists |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL377714A1 (pl) * | 2002-11-26 | 2006-02-06 | Cold Spring Harbor Laboratory | Białka oddziałujące z receptorową tyrozynową fosfatazą białkową DEP-1 oraz sposoby ich wykorzystania |
| US9044503B2 (en) | 2004-08-27 | 2015-06-02 | University Of Kentucky Research Foundation | Amyloid peptide inactivating enzyme to treat alzheimer's disease peripherally |
| WO2006069203A2 (en) | 2004-12-22 | 2006-06-29 | California Institute Of Technology | Methods for proteomic profiling using non-natural amino acids |
| WO2009089635A1 (en) | 2008-01-16 | 2009-07-23 | Neurodyn, Inc. | Treating neurodegenerative diseases with progranulin (pgrn) |
| KR20100054711A (ko) | 2008-11-14 | 2010-05-25 | 메디포스트(주) | 간엽 줄기세포 또는 이의 배양액을 포함하는 신경질환의 예방 또는 치료용 조성물 |
| US20120183509A1 (en) | 2009-04-28 | 2012-07-19 | Harald Neumann | Microglial precursor cells for the treatment of malignant neoplasms of the central nervous system |
| WO2010144678A2 (en) | 2009-06-10 | 2010-12-16 | The General Hospital Corporation | Generation of vascularized human heart tissue and uses thereof |
| JP6312436B2 (ja) | 2010-11-16 | 2018-04-18 | ニューロダイン ライフ サイエンシズ インコーポレイテッドＮｅｕｒｏｄｙｎ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． | ネプリライシンの発現および活性を増大させるための方法および医薬組成物 |
| DK2694644T3 (en) | 2011-03-30 | 2018-04-16 | Cellular Dynamics Int Inc | Priming of pluripotent stem cells for neural differentiation |
| EP3092305B1 (en) | 2014-01-09 | 2023-08-02 | Kyushu University, National University Corporation | Method of producing microglial cells |
| WO2016109813A2 (en) | 2014-12-31 | 2016-07-07 | Wisconsin Alumni Research Foundation | Human pluripotent stem cell-based models for predictive developmental neural toxicity |
| US10081792B2 (en) | 2014-12-31 | 2018-09-25 | Wisconsin Alumni Research Foundation | Derivation of human microglia from pluripotent stem cells |
| JP6774952B2 (ja) | 2015-01-16 | 2020-10-28 | エージェンシー フォー サイエンス， テクノロジー アンド リサーチ | 多能性幹細胞のマクロファージへの分化 |
| WO2016123100A1 (en) | 2015-01-26 | 2016-08-04 | Fate Therapeutics, Inc. | Methods and compositions for inducing hematopoietic cell differentiation |
| WO2016210313A1 (en) | 2015-06-24 | 2016-12-29 | Whitehead Institute For Biomedical Research | Culture medium for generating microglia from pluripotent stem cells and related methods |
| JP7235507B2 (ja) | 2016-03-03 | 2023-03-08 | ニューヨーク ステム セル ファウンデーション インコーポレイテッド | 多能性幹細胞由来のミクログリアならびにその作製および使用方法 |
| US20170369904A1 (en) | 2016-06-22 | 2017-12-28 | Xcell Biosciences, Inc. | Methods for increasing cell culture transfection efficiency and cellular reprogramming |
| JP6963555B2 (ja) | 2016-09-02 | 2021-11-10 | タカラバイオ株式会社 | 多能性幹細胞からミクログリアを得る方法 |
| JP7248571B2 (ja) | 2016-10-05 | 2023-03-29 | フジフィルム セルラー ダイナミクス，インコーポレイテッド | ＭｅＣＰ２が破壊された誘導多能性幹細胞からの成熟系列の生成 |
| US11957713B2 (en) | 2016-10-14 | 2024-04-16 | Children's Medical Center Corporation | Compositions and methods for treating diseases and disorders of the central nervous system |
| EP4272551A3 (en) | 2017-02-28 | 2024-03-06 | The Regents of the University of California | Differentiation and use of human microglia-like cells from pluripotent stem cells and hematopoietic progenitors |
| WO2019118951A2 (en) | 2017-12-15 | 2019-06-20 | Duke University | Compositions and methods of enhancing the homing and/or engraftment of hematopoietic cells in the central nervous system |
| WO2019246273A1 (en) * | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor |
| EP3833762A4 (en) * | 2018-08-09 | 2022-09-28 | Verseau Therapeutics, Inc. | Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof |
| US12612599B2 (en) * | 2018-09-10 | 2026-04-28 | Savanna Biotherapeutics, Inc. | Compositions and methods for microglia replacement therapy |
| WO2020069515A1 (en) | 2018-09-28 | 2020-04-02 | Memorial Sloan-Kettering Cancer Center | Stem cell-derived human microglial cells, methods of making and methods of use |
| US12419915B2 (en) | 2019-03-13 | 2025-09-23 | The Broad Institute, Inc. | Microglial progenitors for regeneration of functional microglia in the central nervous system and therapeutics uses thereof |
| WO2020232512A1 (en) | 2019-05-22 | 2020-11-26 | The Council Of The Queensland Institute Of Medical Research | Microglial cells and methods of use thereof |
| AU2020293287A1 (en) | 2019-06-14 | 2022-01-06 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of multiple lineages from induced pluripotent stem cells using charged surfaces |
| WO2021026294A1 (en) | 2019-08-06 | 2021-02-11 | Children's Medical Center Corporation | Methods and compositions for reconstituting microglia |
| US11866734B2 (en) | 2019-08-26 | 2024-01-09 | Taipei Veterans General Hospital | Super enhancer for driving pluripotency network and stemness circuitry |
| WO2021221879A1 (en) | 2020-05-01 | 2021-11-04 | Albert Einstein College Of Medicine | Compositions and methods for using transplanted microglia as a vehicle for widespread delivery of cells and other biologic agents to the brain |
| WO2021247710A2 (en) | 2020-06-02 | 2021-12-09 | The Regents Of The University Of California | Stem-cell based biomarker discovery |
| GB202011871D0 (en) | 2020-07-30 | 2020-09-16 | Cambridge Entpr Ltd | Composition and method |
| WO2022040798A1 (en) | 2020-08-25 | 2022-03-03 | University Health Network | Compositions and methods for generating human yolk sac-like hematopoietic cells |
| CA3215311A1 (en) | 2021-04-01 | 2022-10-06 | The Regents Of The University Of California | Genetic modification of mammalian cells to confer resistance to csf1r antagonists |
-
2022
- 2022-04-01 CA CA3215311A patent/CA3215311A1/en active Pending
- 2022-04-01 EP EP22782325.9A patent/EP4314003A4/en active Pending
- 2022-04-01 DE DE112022000079.1T patent/DE112022000079T5/de not_active Withdrawn
- 2022-04-01 AU AU2022252407A patent/AU2022252407A1/en active Pending
- 2022-04-01 DE DE202022003066.5U patent/DE202022003066U1/de not_active Withdrawn - After Issue
- 2022-04-01 WO PCT/US2022/023139 patent/WO2022212897A1/en not_active Ceased
- 2022-04-01 JP JP2023559849A patent/JP2024513003A/ja active Pending
- 2022-04-01 DE DE202022003132.7U patent/DE202022003132U1/de active Active
- 2022-04-01 DE DE202022002866.0U patent/DE202022002866U1/de active Active
- 2022-04-01 GB GB2219686.9A patent/GB2612467B/en active Active
- 2022-12-21 US US18/069,543 patent/US12421517B2/en active Active
- 2022-12-21 US US18/069,631 patent/US20230248775A1/en not_active Abandoned
-
2024
- 2024-06-11 US US18/739,622 patent/US20250002920A1/en active Pending
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