JP2024511853A5 - - Google Patents
Info
- Publication number
- JP2024511853A5 JP2024511853A5 JP2023560403A JP2023560403A JP2024511853A5 JP 2024511853 A5 JP2024511853 A5 JP 2024511853A5 JP 2023560403 A JP2023560403 A JP 2023560403A JP 2023560403 A JP2023560403 A JP 2023560403A JP 2024511853 A5 JP2024511853 A5 JP 2024511853A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- domain
- queel
- amino acid
- gfral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2104556.2 | 2021-03-31 | ||
| GBGB2104556.2A GB202104556D0 (en) | 2021-03-31 | 2021-03-31 | Therapeutic inhibitors of GDF15 signalling |
| GBGB2107331.7A GB202107331D0 (en) | 2021-05-21 | 2021-05-21 | Therapeutic inhibitors of GDF15 signalling |
| GB2107331.7 | 2021-05-21 | ||
| GB2108170.8 | 2021-06-08 | ||
| GBGB2108170.8A GB202108170D0 (en) | 2021-06-08 | 2021-06-08 | Theraputic inhibitors of GDF15 Signalling |
| PCT/EP2022/058669 WO2022207846A1 (en) | 2021-03-31 | 2022-03-31 | Therapeutic inhibitors of gdf15 signalling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024511853A JP2024511853A (ja) | 2024-03-15 |
| JP2024511853A5 true JP2024511853A5 (https=) | 2025-04-07 |
Family
ID=81580347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023560403A Pending JP2024511853A (ja) | 2021-03-31 | 2022-03-31 | Ｇｄｆ１５シグナル伝達の治療的阻害剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240182585A1 (https=) |
| EP (1) | EP4314071A1 (https=) |
| JP (1) | JP2024511853A (https=) |
| KR (1) | KR20230165285A (https=) |
| AU (1) | AU2022251923A1 (https=) |
| BR (1) | BR112023020152A2 (https=) |
| CA (1) | CA3215737A1 (https=) |
| CO (1) | CO2023013791A2 (https=) |
| IL (1) | IL307382A (https=) |
| MX (1) | MX2023011655A (https=) |
| WO (1) | WO2022207846A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY194669A (en) | 2016-03-31 | 2022-12-12 | Ngm Biopharmaceuticals Inc | Binding Proteins and Methods of use Thereof |
| IT202300006387A1 (it) * | 2023-03-31 | 2024-10-01 | Univ Degli Studi Roma La Sapienza | Inibitore del recettore gfral per uso nel trattamento della sclerosi laterale amiotrofica |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US7083784B2 (en) | 2000-12-12 | 2006-08-01 | Medimmune, Inc. | Molecules with extended half-lives, compositions and uses thereof |
| US20050266425A1 (en) | 2003-12-31 | 2005-12-01 | Vaccinex, Inc. | Methods for producing and identifying multispecific antibodies |
| EP2441466B1 (en) | 2004-04-13 | 2014-07-23 | St Vincent's Hospital Sydney Limited | MIC-1 inhibiting agent |
| JOP20080381B1 (ar) | 2007-08-23 | 2023-03-28 | Amgen Inc | بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9) |
| US8901129B2 (en) | 2009-12-11 | 2014-12-02 | Genecode As | Methods of facilitating neural cell survival using GDNF family ligand (GFL) mimetics or RET signaling pathway activators |
| WO2013012648A1 (en) | 2011-07-15 | 2013-01-24 | Emory University | Gdf15 in diagnostic and therapeutic applications |
| CN102321173B (zh) | 2011-08-12 | 2013-04-03 | 中国医学科学院肿瘤研究所 | 人源化巨噬细胞抑制因子1单克隆抗体及其应用 |
| RS59045B1 (sr) | 2012-09-26 | 2019-08-30 | Univ Wuerzburg J Maximilians | Monoklonalna antitela za faktor 15 rasta i diferencijacije (gdf-15) |
| ES2791183T3 (es) | 2012-12-21 | 2020-11-03 | Aveo Pharmaceuticals Inc | Anticuerpos anti-GDF15 |
| RS59700B1 (sr) | 2014-03-26 | 2020-01-31 | Univ Wuerzburg J Maximilians | Monoklonalna antitela za faktor 15 (gdf-15) rasta i diferencijacije, i njihove upotrebe u lečenju kancerske kaheksije i kancera |
| PL3197493T3 (pl) | 2014-09-25 | 2021-08-23 | Aveo Pharmaceuticals Inc. | Sposoby odwracania kacheksji i przedłużania przeżycia obejmujące podanie modulatora gdf15 i środka przeciwnowotworowego |
| CN108463246B (zh) | 2015-10-02 | 2025-02-28 | 尤利乌斯·马克西米利安维尔茨堡大学 | 使用人生长分化因子15(gdf-15)抑制剂和免疫检查点阻断剂的联合治疗 |
| WO2017121865A1 (en) | 2016-01-15 | 2017-07-20 | Novo Nordisk A/S | Mic-1 receptor and uses thereof |
| CN108697795A (zh) * | 2016-02-29 | 2018-10-23 | 伊莱利利公司 | Gfral受体疗法 |
| US20170299608A1 (en) | 2016-03-04 | 2017-10-19 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for modulating body weight |
| MY194669A (en) | 2016-03-31 | 2022-12-12 | Ngm Biopharmaceuticals Inc | Binding Proteins and Methods of use Thereof |
| WO2017189724A1 (en) | 2016-04-27 | 2017-11-02 | Novartis Ag | Antibodies against growth differentiation factor 15 and uses thereof |
-
2022
- 2022-03-31 US US18/284,952 patent/US20240182585A1/en active Pending
- 2022-03-31 WO PCT/EP2022/058669 patent/WO2022207846A1/en not_active Ceased
- 2022-03-31 IL IL307382A patent/IL307382A/en unknown
- 2022-03-31 JP JP2023560403A patent/JP2024511853A/ja active Pending
- 2022-03-31 EP EP22720935.0A patent/EP4314071A1/en active Pending
- 2022-03-31 CA CA3215737A patent/CA3215737A1/en active Pending
- 2022-03-31 MX MX2023011655A patent/MX2023011655A/es unknown
- 2022-03-31 BR BR112023020152A patent/BR112023020152A2/pt unknown
- 2022-03-31 AU AU2022251923A patent/AU2022251923A1/en active Pending
- 2022-03-31 KR KR1020237037287A patent/KR20230165285A/ko active Pending
-
2023
- 2023-10-19 CO CONC2023/0013791A patent/CO2023013791A2/es unknown
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