JP2024511473A5 - - Google Patents
Info
- Publication number
- JP2024511473A5 JP2024511473A5 JP2023558979A JP2023558979A JP2024511473A5 JP 2024511473 A5 JP2024511473 A5 JP 2024511473A5 JP 2023558979 A JP2023558979 A JP 2023558979A JP 2023558979 A JP2023558979 A JP 2023558979A JP 2024511473 A5 JP2024511473 A5 JP 2024511473A5
- Authority
- JP
- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163165543P | 2021-03-24 | 2021-03-24 | |
| US63/165,543 | 2021-03-24 | ||
| PCT/US2022/021790 WO2022204430A1 (en) | 2021-03-24 | 2022-03-24 | Double-stranded sirna having patterned chemical modifications |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024511473A JP2024511473A (ja) | 2024-03-13 |
| JP2024511473A5 true JP2024511473A5 (https=) | 2025-04-01 |
| JPWO2022204430A5 JPWO2022204430A5 (https=) | 2025-04-01 |
Family
ID=83397880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023558979A Pending JP2024511473A (ja) | 2021-03-24 | 2022-03-24 | パターン化化学修飾を有する二本鎖ｓｉｒｎａ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240182892A1 (https=) |
| EP (1) | EP4313075A4 (https=) |
| JP (1) | JP2024511473A (https=) |
| CN (1) | CN117597133A (https=) |
| AU (1) | AU2022242899A1 (https=) |
| CA (1) | CA3214660A1 (https=) |
| WO (1) | WO2022204430A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL319764A (en) * | 2022-09-28 | 2025-05-01 | Atalanta Therapeutics Inc | Compositions and methods for treating Huntington's disease |
| WO2024169770A1 (zh) * | 2023-02-17 | 2024-08-22 | 苏州时安生物技术有限公司 | 一种抑制SCN9A基因表达的siRNA、其药物组合物及用途 |
| WO2025085593A1 (en) * | 2023-10-18 | 2025-04-24 | University Of Massachusetts | Oligonucleotides with ethylene glycol modification |
| WO2025108284A1 (en) * | 2023-11-20 | 2025-05-30 | Shanghai Argo Biopharmaceutical Co., Ltd. | Compositions and methods for inhibiting expression of sodium voltage-gated channel alpha subunit 9 (scn9a) |
| TW202602463A (zh) | 2024-03-22 | 2026-01-16 | 日商武田藥品工業股份有限公司 | 用於抑制細胞色素ｐ４５０家族７次家族ａ成員１（ｃｙｐ７ａ１）表現之組成物及方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9181551B2 (en) * | 2002-02-20 | 2015-11-10 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
| US10125369B2 (en) * | 2012-12-05 | 2018-11-13 | Alnylam Pharmaceuticals, Inc. | PCSK9 iRNA compositions and methods of use thereof |
| EP3277811B1 (en) * | 2015-04-03 | 2020-12-23 | University of Massachusetts | Fully stabilized asymmetric sirna |
| EA201792263A1 (ru) * | 2015-04-13 | 2018-08-31 | Элнилэм Фармасьютикалз, Инк. | КОМПОЗИЦИИ НА ОСНОВЕ iRNA ПРОТИВ АНГИОПОЭТИН-ПОДОБНОГО БЕЛКА 3 (ANGPTL3) И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| CN108138182B (zh) * | 2015-07-31 | 2022-08-19 | 阿尔尼拉姆医药品有限公司 | 甲状腺素运载蛋白(TTR)iRNA组合物及其治疗或预防TTR相关疾病的使用方法 |
| JP7155239B2 (ja) * | 2017-04-05 | 2022-10-18 | サイレンス・セラピューティクス・ゲーエムベーハー | 産物及び組成物 |
| JP7406793B2 (ja) * | 2017-06-23 | 2023-12-28 | ユニバーシティー オブ マサチューセッツ | ２テイル自己デリバリー型ｓｉＲＮＡおよび関連方法 |
| IL274611B2 (en) * | 2017-11-13 | 2024-10-01 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of a target gene comprising phosphorodithioate linkages |
| CN113811311A (zh) * | 2019-03-15 | 2021-12-17 | 马萨诸塞大学 | 用于组织特异性apoe调节的寡核苷酸 |
| US20200385737A1 (en) * | 2019-03-29 | 2020-12-10 | University Of Massachusetts | OLIGONUCLEOTIDE-BASED MODULATION OF C9orf72 |
| JP2022545118A (ja) * | 2019-08-23 | 2022-10-25 | ユニバーシティー オブ マサチューセッツ | Ｏ－メチルリッチ完全安定化オリゴヌクレオチド |
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2022
- 2022-03-24 WO PCT/US2022/021790 patent/WO2022204430A1/en not_active Ceased
- 2022-03-24 CN CN202280037397.4A patent/CN117597133A/zh active Pending
- 2022-03-24 AU AU2022242899A patent/AU2022242899A1/en active Pending
- 2022-03-24 US US18/283,666 patent/US20240182892A1/en active Pending
- 2022-03-24 EP EP22776673.0A patent/EP4313075A4/en active Pending
- 2022-03-24 CA CA3214660A patent/CA3214660A1/en active Pending
- 2022-03-24 JP JP2023558979A patent/JP2024511473A/ja active Pending