JP2024511079A - 抗セラミド抗体による創傷治癒の強化 - Google Patents

抗セラミド抗体による創傷治癒の強化 Download PDF

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Publication number
JP2024511079A
JP2024511079A JP2023557734A JP2023557734A JP2024511079A JP 2024511079 A JP2024511079 A JP 2024511079A JP 2023557734 A JP2023557734 A JP 2023557734A JP 2023557734 A JP2023557734 A JP 2023557734A JP 2024511079 A JP2024511079 A JP 2024511079A
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Japan
Prior art keywords
amino acid
acid sequence
seq
antigen
wound
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JP2023557734A
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English (en)
Japanese (ja)
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JP2024511079A5 (cg-RX-API-DMAC7.html
Inventor
リチャード コールスニック
ジュリア ブシク
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Michigan State University
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Michigan State University
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Application filed by Michigan State University filed Critical Michigan State University
Publication of JP2024511079A publication Critical patent/JP2024511079A/ja
Publication of JP2024511079A5 publication Critical patent/JP2024511079A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2023557734A 2021-03-16 2022-03-15 抗セラミド抗体による創傷治癒の強化 Pending JP2024511079A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163161758P 2021-03-16 2021-03-16
US63/161,758 2021-03-16
PCT/US2022/020385 WO2022197703A1 (en) 2021-03-16 2022-03-15 Wound healing enhancement with anti-ceramide antibodies

Publications (2)

Publication Number Publication Date
JP2024511079A true JP2024511079A (ja) 2024-03-12
JP2024511079A5 JP2024511079A5 (cg-RX-API-DMAC7.html) 2025-09-03

Family

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Family Applications (1)

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JP2023557734A Pending JP2024511079A (ja) 2021-03-16 2022-03-15 抗セラミド抗体による創傷治癒の強化

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Country Link
US (1) US20240158487A1 (cg-RX-API-DMAC7.html)
EP (1) EP4308231A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024511079A (cg-RX-API-DMAC7.html)
KR (1) KR20230162788A (cg-RX-API-DMAC7.html)
CN (1) CN117320750A (cg-RX-API-DMAC7.html)
BR (1) BR112023018758A2 (cg-RX-API-DMAC7.html)
CA (1) CA3212333A1 (cg-RX-API-DMAC7.html)
IL (1) IL305920A (cg-RX-API-DMAC7.html)
MX (1) MX2023010858A (cg-RX-API-DMAC7.html)
WO (1) WO2022197703A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12655229B2 (en) 2020-03-18 2026-06-16 Memorial Sloan Kettering Cancer Center Anti-ceramide antibodies

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015523970A (ja) * 2012-05-25 2015-08-20 スローン ケタリング インスティテュート フォア キャンサー リサーチ Ｇｉ症候群及び移植片対宿主病の治療方法
JP2017527544A (ja) * 2014-08-07 2017-09-21 メモリアル スローン−ケタリング キャンサー センター 抗セラミド抗体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2152287B1 (en) * 2007-05-06 2014-04-02 Sloan Kettering Institute For Cancer Research Methods for treating and preventing gi syndrome and graft versus host disease
US8129341B2 (en) * 2008-08-25 2012-03-06 New York University Methods for treating diabetic wounds
US12655229B2 (en) * 2020-03-18 2026-06-16 Memorial Sloan Kettering Cancer Center Anti-ceramide antibodies

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015523970A (ja) * 2012-05-25 2015-08-20 スローン ケタリング インスティテュート フォア キャンサー リサーチ Ｇｉ症候群及び移植片対宿主病の治療方法
JP2017527544A (ja) * 2014-08-07 2017-09-21 メモリアル スローン−ケタリング キャンサー センター 抗セラミド抗体

Also Published As

Publication number Publication date
CA3212333A1 (en) 2022-09-22
CN117320750A (zh) 2023-12-29
MX2023010858A (es) 2023-11-23
WO2022197703A1 (en) 2022-09-22
US20240158487A1 (en) 2024-05-16
IL305920A (en) 2023-11-01
EP4308231A4 (en) 2025-01-29
KR20230162788A (ko) 2023-11-28
EP4308231A1 (en) 2024-01-24
BR112023018758A2 (pt) 2023-11-28

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