BR112023018758A2 - Intensificação de cicatrização de ferida com anticorpos anticeramida - Google Patents

Intensificação de cicatrização de ferida com anticorpos anticeramida

Info

Publication number
BR112023018758A2
BR112023018758A2 BR112023018758A BR112023018758A BR112023018758A2 BR 112023018758 A2 BR112023018758 A2 BR 112023018758A2 BR 112023018758 A BR112023018758 A BR 112023018758A BR 112023018758 A BR112023018758 A BR 112023018758A BR 112023018758 A2 BR112023018758 A2 BR 112023018758A2
Authority
BR
Brazil
Prior art keywords
wound
intensification
antibodies
anticeramide
wound healing
Prior art date
Application number
BR112023018758A
Other languages
English (en)
Inventor
Julia Busik
Richard Kolesnick
Original Assignee
Univ Michigan State
Memorial Hospital For Cancer And Allied Diseases
Memorial Sloan Kettering Cancer Center
Sloan Kettering Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan State, Memorial Hospital For Cancer And Allied Diseases, Memorial Sloan Kettering Cancer Center, Sloan Kettering Inst Cancer Res filed Critical Univ Michigan State
Publication of BR112023018758A2 publication Critical patent/BR112023018758A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

intensificação de cicatrização de ferida com anticorpos anticeramida. a presente divulgação fornece composições e métodos para melhorar ou acelerar a cicatrização de uma ferida. em várias modalidades, os métodos compreendem o uso de anticorpos anticeramida e fragmentos de anticorpos. em algumas modalidades, a ferida é uma ferida crônica. em algumas modalidades, a ferida é uma ferida diabética.
BR112023018758A 2021-03-16 2022-03-15 Intensificação de cicatrização de ferida com anticorpos anticeramida BR112023018758A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163161758P 2021-03-16 2021-03-16
PCT/US2022/020385 WO2022197703A1 (en) 2021-03-16 2022-03-15 Wound healing enhancement with anti-ceramide antibodies

Publications (1)

Publication Number Publication Date
BR112023018758A2 true BR112023018758A2 (pt) 2023-11-28

Family

ID=83321040

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023018758A BR112023018758A2 (pt) 2021-03-16 2022-03-15 Intensificação de cicatrização de ferida com anticorpos anticeramida

Country Status (10)

Country Link
US (1) US20240158487A1 (pt)
EP (1) EP4308231A1 (pt)
JP (1) JP2024511079A (pt)
KR (1) KR20230162788A (pt)
CN (1) CN117320750A (pt)
BR (1) BR112023018758A2 (pt)
CA (1) CA3212333A1 (pt)
IL (1) IL305920A (pt)
MX (1) MX2023010858A (pt)
WO (1) WO2022197703A1 (pt)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010027802A2 (en) * 2008-08-25 2010-03-11 New York University Methods for treating diabetic wounds
JP6257600B2 (ja) * 2012-05-25 2018-01-10 スローン ケタリング インスティテュート フォア キャンサー リサーチ Gi症候群及び移植片対宿主病の治療方法

Also Published As

Publication number Publication date
WO2022197703A1 (en) 2022-09-22
KR20230162788A (ko) 2023-11-28
US20240158487A1 (en) 2024-05-16
MX2023010858A (es) 2023-11-23
EP4308231A1 (en) 2024-01-24
CA3212333A1 (en) 2022-09-22
CN117320750A (zh) 2023-12-29
IL305920A (en) 2023-11-01
JP2024511079A (ja) 2024-03-12

Similar Documents

Publication Publication Date Title
BR112022017930A2 (pt) Anticorpos anticoronavírus e métodos de uso
CL2020001974A1 (es) Anticuerpos anti-trem2 y métodos para utilizarlos. (divisional solicitud 201903093)
AR114541A1 (es) Constructos de anticuerpos para cldn18.2 y cd3
AR115418A1 (es) ANTICUERPOS ANTI-SIRPA (PROTEÍNA REGULADORA DE SEÑALES a) Y MÉTODOS DE USO DE LOS MISMOS
BR112015021595A2 (pt) anticorpos anti-tgf-beta engenheirados e fragmentos de ligação do antígeno
BR112022011570A2 (pt) Anticorpos anti-mertk e métodos de uso dos mesmos
BR112015017307A2 (pt) composições de espécies com baixa acidez e métodos para produção e uso das mesmas
BR112015032690A2 (pt) uso de moléculas inibidoras de semaforina-4d em combinação com uma terapia imunomoduladora para inibir crescimento tumoral e metástases
AR074360A1 (es) Anticuerpo monoclonal o fragmento de union a antigeno del mismo composicion farmaceutica que lo comprende y su uso para preparar dicha composicion
BR112016011401A2 (pt) moduladores de aplnr e utilizações dos mesmos
AR060017A1 (es) Composiciones y metodos de uso para anticuerpos de dickkopf -1
BR112013008407A2 (pt) antígenos de clostridium difficile
CL2021001260A1 (es) Anticuerpos anti-sirpa humanizados
BR112019008279A2 (pt) uso de beta-catenina como um biomarcador para tratamento de cânceres usando anticorpo anti-dkk-1
BR112022024262A2 (pt) Métodos de tratamento de nefropatia por iga com um anticorpo de ligação a april
ECSP21022299A (es) Anticuerpos de anti-cd33 y métodos para usarlos
BR112014024751A2 (pt) antígenos de clostridium difficile
BR112022021910A2 (pt) Inibidores da proteína bcl-2
BR112021012056A2 (pt) Inibidor da expressão gênica do hbv, agente que reduz a carga antigênica de hbv, composições para uso no tratamento de uma infecção crônica por hbv, usos de um inibidor da expressão gênica do hbv e de um agente que reduz a carga antigênica de hbv, métodos de tratamento da infecção crônica por hbv e kit
DOP2022000129A (es) Anticuerpos contra la integrina alfa 11 beta 1
BR112014016950A2 (pt) métodos de promoção da cicatrização de úlceras diabéticas utilizando beta-hidróxi-beta-metilbutirato com arginina e glutamina
AU2021269176A8 (en) Single domain antibodies binding to SARS-CoV-2 spike protein
BR112021011351A2 (pt) Uso de anticorpos il-1 beta no tratamento ou prevenção de síndrome mielodisplásica
BR112023018758A2 (pt) Intensificação de cicatrização de ferida com anticorpos anticeramida
BR112019010331A2 (pt) composição farmacêutica para evitar a dependência de opioides