JP2024510465A5 - - Google Patents

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Publication number
JP2024510465A5
JP2024510465A5 JP2023556784A JP2023556784A JP2024510465A5 JP 2024510465 A5 JP2024510465 A5 JP 2024510465A5 JP 2023556784 A JP2023556784 A JP 2023556784A JP 2023556784 A JP2023556784 A JP 2023556784A JP 2024510465 A5 JP2024510465 A5 JP 2024510465A5
Authority
JP
Japan
Prior art keywords
seq
oligonucleotide sequence
sequence
oligonucleotide
amplification product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023556784A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024510465A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/056496 external-priority patent/WO2022194756A2/en
Publication of JP2024510465A publication Critical patent/JP2024510465A/ja
Publication of JP2024510465A5 publication Critical patent/JP2024510465A5/ja
Pending legal-status Critical Current

Links

JP2023556784A 2021-03-15 2022-03-14 スパイクタンパク質の変異を有する重症急性呼吸器症候群コロナウイルス2(sars-cov-2)バリアントを検出するための組成物および方法 Pending JP2024510465A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163161398P 2021-03-15 2021-03-15
US63/161,398 2021-03-15
US202163168718P 2021-03-31 2021-03-31
US63/168,718 2021-03-31
PCT/EP2022/056496 WO2022194756A2 (en) 2021-03-15 2022-03-14 Compositions and methods for detecting severe acute respiratory syndrome coronavirus 2 (sars-cov-2) variants having spike protein mutations

Publications (2)

Publication Number Publication Date
JP2024510465A JP2024510465A (ja) 2024-03-07
JP2024510465A5 true JP2024510465A5 (enExample) 2025-01-23

Family

ID=81326309

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023556784A Pending JP2024510465A (ja) 2021-03-15 2022-03-14 スパイクタンパク質の変異を有する重症急性呼吸器症候群コロナウイルス2(sars-cov-2)バリアントを検出するための組成物および方法

Country Status (4)

Country Link
US (1) US20220290221A1 (enExample)
EP (1) EP4308726A2 (enExample)
JP (1) JP2024510465A (enExample)
WO (1) WO2022194756A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023536962A (ja) * 2020-08-06 2023-08-30 エフ. ホフマン-ラ ロシュ アーゲー 重症急性呼吸器症候群コロナウイルス2(sars-2)、インフルエンザa及びインフルエンザbの検出のための組成物及び方法
US20240409984A1 (en) * 2023-06-09 2024-12-12 Revvity Health Sciences, Inc. Methods for detecting mutations in target nucleic acids using dual probes

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135587B2 (en) 1983-02-22 2002-12-18 Syngene, Inc. Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4996143A (en) 1985-12-23 1991-02-26 Syngene, Inc. Fluorescent stokes shift probes for polynucleotide hybridization
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5035996A (en) 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5683896A (en) 1989-06-01 1997-11-04 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
EP1067134B1 (en) 1991-11-07 2004-07-28 Nanotronics, Inc. Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system
ES2253778T3 (es) 1996-06-04 2006-06-01 University Of Utah Research Foundation Sistema y metodos de monitorizacion de una amplificacion de adn mediante fluorescencia.
JP4540754B2 (ja) 1996-06-04 2010-09-08 ユニバーシティ オブ ユタ リサーチ ファウンデーション Pcr中のハイブリダイゼーションのモニタリング
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
EP0866071B1 (en) * 1997-03-20 2004-10-20 F. Hoffmann-La Roche Ag Modified primers
US6794499B2 (en) 1997-09-12 2004-09-21 Exiqon A/S Oligonucleotide analogues
WO2005092038A2 (en) * 2004-03-22 2005-10-06 The Johns Hopkins University Methods for the detection of nucleic acid differences
ES2371088T3 (es) 2005-10-05 2011-12-27 F. Hoffmann-La Roche Ag Transferencia de energía no fluorescente.
EP2914753A4 (en) * 2012-10-31 2016-06-08 Becton Dickinson Co SELECTIVE AMPLIFICATION AND REAL-TIME PCR DETECTION OF RARE MUTATIONS
US20150176060A1 (en) * 2013-12-20 2015-06-25 Roche Molecular Systems, Inc. Method For Coding Of Multiple PCR Reactions For Assay Recognition
WO2015147370A1 (en) * 2014-03-28 2015-10-01 Seegene, Inc. Detection of target nucleic acid sequences using different detection temperatures
JP6856544B2 (ja) * 2015-04-17 2021-04-07 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 遺伝子融合体を検出するための多重pcr
CN107849606A (zh) * 2015-04-20 2018-03-27 尼欧基因组学实验室股份有限公司 提高下一代测序灵敏度的方法
CA3224392A1 (en) * 2015-04-24 2016-10-27 Becton, Dickinson And Company Multiplex detection of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis
RU2674338C1 (ru) * 2017-10-09 2018-12-07 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Способ анализа соматических мутаций в генах BRAF, NRAS и KIT с использованием LNA-блокирующей мультиплексной ПЦР и последующей гибридизацией с олигонуклеотидным биологическим микрочипом (биочипом)
WO2021152181A1 (en) * 2020-01-30 2021-08-05 Biomedrex Ab Virus therapy
CN110982945B (zh) * 2020-03-04 2020-06-09 珠海丽珠试剂股份有限公司 一种检测2019新型冠状病毒的核酸组合物、试剂盒以及方法
US20210292820A1 (en) * 2020-03-20 2021-09-23 Applied Dna Sciences, Inc. Compositions and methods for detecting and treating sars-cov-2
WO2021202158A1 (en) * 2020-04-01 2021-10-07 President And Fellows Of Harvard College Nested rpa and competitive reference standard
CN112111597B (zh) * 2020-04-28 2023-07-21 安徽同科生物科技有限公司 一种免核酸提取快速检测新型冠状病毒2019-nCoV核酸的荧光PCR试剂盒
CN111254228B (zh) * 2020-05-06 2020-09-11 上海思路迪医学检验所有限公司 一种检测新型冠状病毒和流感病毒的试剂盒
CN111560478B (zh) * 2020-05-27 2020-11-13 广州凯普医药科技有限公司 一种一步法反转录PCR结合Sanger测序检测新型冠状病毒的试剂盒
CN111534643B (zh) * 2020-07-10 2020-10-09 上海科技大学 一种检测呼吸道病原的核酸的试剂盒、检测方法及应用
WO2022020393A1 (en) * 2020-07-20 2022-01-27 Mammoth Biosciences, Inc. High-throughput single-chamber programmable nuclease assay
WO2022044011A1 (en) * 2020-08-25 2022-03-03 B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University Oligonucleotides and methods of using same
CN113637798A (zh) * 2021-08-09 2021-11-12 南昌大学 检测新冠病毒Alpha毒株S基因Δ69/70HV缺失突变位点的引物、探针及其应用

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