JP2024508903A5 - - Google Patents
Info
- Publication number
- JP2024508903A5 JP2024508903A5 JP2023553432A JP2023553432A JP2024508903A5 JP 2024508903 A5 JP2024508903 A5 JP 2024508903A5 JP 2023553432 A JP2023553432 A JP 2023553432A JP 2023553432 A JP2023553432 A JP 2023553432A JP 2024508903 A5 JP2024508903 A5 JP 2024508903A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- haloalkyl
- independently
- miro1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163156806P | 2021-03-04 | 2021-03-04 | |
| US63/156,806 | 2021-03-04 | ||
| US202163228505P | 2021-08-02 | 2021-08-02 | |
| US63/228,505 | 2021-08-02 | ||
| PCT/US2022/018682 WO2022216386A2 (en) | 2021-03-04 | 2022-03-03 | T-type calcium channel antagonists and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024508903A JP2024508903A (ja) | 2024-02-28 |
| JP2024508903A5 true JP2024508903A5 (https=) | 2025-03-11 |
Family
ID=83545681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023553432A Pending JP2024508903A (ja) | 2021-03-04 | 2022-03-03 | Ｔ型カルシウムチャネルアンタゴニストおよびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240190865A1 (https=) |
| EP (1) | EP4301759A4 (https=) |
| JP (1) | JP2024508903A (https=) |
| KR (1) | KR20230167035A (https=) |
| AU (1) | AU2022255225A1 (https=) |
| BR (1) | BR112023016601A2 (https=) |
| CA (1) | CA3208202A1 (https=) |
| IL (1) | IL305381A (https=) |
| MX (1) | MX2023010175A (https=) |
| WO (1) | WO2022216386A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024081653A2 (en) * | 2022-10-12 | 2024-04-18 | Acurex Biosciences Corporation | Methods of lowering miro2 to treat neurodegenerative diseases |
| EP4611744A1 (en) * | 2022-10-31 | 2025-09-10 | Acurex Biosciences Corporation | Methods of reducing miro1 or phosphorylated alpha-synuclein |
| CN116813444A (zh) * | 2023-06-28 | 2023-09-29 | 福建凯昕药业有限公司 | 一种1-溴-4-(1-(三氟甲基)环丙基)苯的制备方法 |
| WO2025257786A1 (en) * | 2024-06-13 | 2025-12-18 | Iama Therapeutics S.R.L. | Benzoimidazole derivatives as nkcc1 inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610701B2 (en) * | 2001-02-09 | 2003-08-26 | Merck & Co., Inc. | Thrombin inhibitors |
| EP2010493B1 (en) * | 2006-04-12 | 2016-01-27 | Merck Sharp & Dohme Corp. | Pyridyl amide t-type calcium channel antagonists |
| AU2008317353B2 (en) * | 2007-10-24 | 2014-08-07 | Merck Sharp & Dohme Llc | Heterocycle phenyl amide T-type calcium channel antagonists |
| JP2011500808A (ja) * | 2007-10-24 | 2011-01-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 複素環アミドｔ型カルシウムチャネルアンタゴニスト |
| EP2493297B1 (en) * | 2009-10-30 | 2016-08-17 | Merck Sharp & Dohme Corp. | Heterocycle amide t-type calcium channel antagonists |
| CN120118971A (zh) * | 2019-09-05 | 2025-06-10 | 小利兰·斯坦福大学托管委员会 | 修饰线粒体功能的方法和化合物 |
-
2022
- 2022-03-03 JP JP2023553432A patent/JP2024508903A/ja active Pending
- 2022-03-03 CA CA3208202A patent/CA3208202A1/en active Pending
- 2022-03-03 AU AU2022255225A patent/AU2022255225A1/en active Pending
- 2022-03-03 MX MX2023010175A patent/MX2023010175A/es unknown
- 2022-03-03 EP EP22785131.8A patent/EP4301759A4/en active Pending
- 2022-03-03 KR KR1020237033323A patent/KR20230167035A/ko active Pending
- 2022-03-03 WO PCT/US2022/018682 patent/WO2022216386A2/en not_active Ceased
- 2022-03-03 US US18/280,096 patent/US20240190865A1/en active Pending
- 2022-03-03 BR BR112023016601A patent/BR112023016601A2/pt unknown
- 2022-03-03 IL IL305381A patent/IL305381A/en unknown
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