JP2024504542A5 - - Google Patents
Info
- Publication number
- JP2024504542A5 JP2024504542A5 JP2023527410A JP2023527410A JP2024504542A5 JP 2024504542 A5 JP2024504542 A5 JP 2024504542A5 JP 2023527410 A JP2023527410 A JP 2023527410A JP 2023527410 A JP2023527410 A JP 2023527410A JP 2024504542 A5 JP2024504542 A5 JP 2024504542A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- alkyl
- compound
- compound according
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021074709 | 2021-02-01 | ||
| CNPCT/CN2021/074709 | 2021-02-01 | ||
| PCT/CN2022/075239 WO2022161496A1 (en) | 2021-02-01 | 2022-01-30 | Sulfonyl benzamide derivatives as bcl-2 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024504542A JP2024504542A (ja) | 2024-02-01 |
| JP2024504542A5 true JP2024504542A5 (https=) | 2024-12-13 |
Family
ID=82562087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023527410A Pending JP2024504542A (ja) | 2021-02-01 | 2022-01-30 | Ｂｃｌ－２阻害剤としてのスルホニルベンズアミド誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12577245B2 (https=) |
| EP (1) | EP4298098A4 (https=) |
| JP (1) | JP2024504542A (https=) |
| CN (1) | CN114835704B (https=) |
| WO (1) | WO2022161496A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024032776A1 (en) * | 2022-08-12 | 2024-02-15 | Fochon Biosciences, Ltd. | Compounds as bcl-2 inhibitors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005049593A2 (en) * | 2003-11-13 | 2005-06-02 | Abbott Laboratories | N-acylsulfonamide apoptosis promoters |
| DK2376480T3 (en) | 2008-12-05 | 2016-09-12 | Abbvie Inc | Sulfonamide derivatives AS BCL-2-selective apoptosis inducing agents for the treatment of cancer and immune diseases |
| US8546399B2 (en) * | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| RU2015141713A (ru) * | 2010-03-25 | 2018-12-28 | Эббви Инк. | Средства, индуцирующие апоптоз, для лечения рака, иммунных и аутоиммунных заболеваний |
| US20140275082A1 (en) * | 2013-03-14 | 2014-09-18 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| US10829488B2 (en) * | 2016-08-05 | 2020-11-10 | The Regents Of The University Of Michigan | N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors |
| EP3565815B1 (en) * | 2017-01-07 | 2024-03-13 | Fochon Pharmaceuticals, Ltd. | Compounds as bcl-2-selective apoptosis-inducing agents |
| CN110759908B (zh) * | 2017-06-26 | 2021-03-12 | 深圳市塔吉瑞生物医药有限公司 | 用于抑制Bcl-2蛋白的N-苯磺酰基苯甲酰胺类化合物及其组合物及应用 |
| WO2019185025A1 (zh) * | 2018-03-30 | 2019-10-03 | 正大天晴药业集团股份有限公司 | 三氟甲基取代的磺酰胺类选择性bcl-2抑制剂 |
| AU2019372640B2 (en) * | 2018-10-29 | 2022-08-04 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Trifluoromethyl-substituted sulfonamide as BCL-2-selective inhibitor |
| US12319689B2 (en) * | 2019-05-24 | 2025-06-03 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Methyl- and trifluoromethyl-containing disubstituted sulfonamide selective BCL-2 inhibitor |
| CN113444078B (zh) * | 2020-03-25 | 2023-07-07 | 中国科学院上海有机化学研究所 | 抗凋亡蛋白Bcl-2抑制剂及其制备方法和应用 |
-
2022
- 2022-01-30 WO PCT/CN2022/075239 patent/WO2022161496A1/en not_active Ceased
- 2022-01-30 CN CN202210113836.7A patent/CN114835704B/zh active Active
- 2022-01-30 EP EP22745367.7A patent/EP4298098A4/en active Pending
- 2022-01-30 US US18/263,249 patent/US12577245B2/en active Active
- 2022-01-30 JP JP2023527410A patent/JP2024504542A/ja active Pending
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