JP2024504503A5 - - Google Patents

Info

Publication number
JP2024504503A5
JP2024504503A5 JP2023546403A JP2023546403A JP2024504503A5 JP 2024504503 A5 JP2024504503 A5 JP 2024504503A5 JP 2023546403 A JP2023546403 A JP 2023546403A JP 2023546403 A JP2023546403 A JP 2023546403A JP 2024504503 A5 JP2024504503 A5 JP 2024504503A5
Authority
JP
Japan
Prior art keywords
nucleic acid
nucleotide
terminal
chain
strand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023546403A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024504503A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/052070 external-priority patent/WO2022162155A1/en
Publication of JP2024504503A publication Critical patent/JP2024504503A/ja
Publication of JP2024504503A5 publication Critical patent/JP2024504503A5/ja
Pending legal-status Critical Current

Links

JP2023546403A 2021-01-30 2022-01-28 脱塩基ヌクレオチドを含有する核酸 Pending JP2024504503A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163143805P 2021-01-30 2021-01-30
US63/143,805 2021-01-30
US202163262316P 2021-10-08 2021-10-08
US63/262,316 2021-10-08
US202163271684P 2021-10-25 2021-10-25
US63/271,684 2021-10-25
PCT/EP2022/052070 WO2022162155A1 (en) 2021-01-30 2022-01-28 Nucleic acids containing abasic nucleotides

Publications (2)

Publication Number Publication Date
JP2024504503A JP2024504503A (ja) 2024-01-31
JP2024504503A5 true JP2024504503A5 (https=) 2025-01-27

Family

ID=87315314

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023546403A Pending JP2024504503A (ja) 2021-01-30 2022-01-28 脱塩基ヌクレオチドを含有する核酸

Country Status (6)

Country Link
US (1) US20230407311A1 (https=)
JP (1) JP2024504503A (https=)
KR (1) KR20230136644A (https=)
AU (1) AU2022212580A1 (https=)
BR (1) BR112023014443A2 (https=)
CA (1) CA3204331A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3204340A1 (en) 2021-01-30 2022-08-04 Ahmad Ali MORTAZAVI Conjugated oligonucleotide compounds, methods of making and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1432724A4 (en) * 2002-02-20 2006-02-01 Sirna Therapeutics Inc RNA inhibition mediated inhibition of MAP KINASE GENES
CA2715289C (en) * 2008-02-11 2019-12-24 Rxi Pharmaceuticals Corporation Modified rnai polynucleotides and uses thereof
WO2011084193A1 (en) * 2010-01-07 2011-07-14 Quark Pharmaceuticals, Inc. Oligonucleotide compounds comprising non-nucleotide overhangs
US20200208152A1 (en) * 2017-09-08 2020-07-02 Mina Therapeutics Limited Stabilized sarna compositions and methods of use
KR20240161202A (ko) * 2017-09-11 2024-11-12 애로우헤드 파마슈티컬스 인코포레이티드 아포지단백질 C-III (APOC3)의 발현을 억제하기 위한 RNAi 작용제 및 조성물
WO2020123410A1 (en) * 2018-12-10 2020-06-18 Amgen Inc. CHEMICALLY-MODIFIED RNAi CONSTRUCTS AND USES THEREOF

Similar Documents

Publication Publication Date Title
US5721218A (en) Oligonucleotides with inverted polarity
JP2023068035A5 (https=)
JP2022544587A5 (https=)
JP2021520207A5 (https=)
EP4022059A1 (en) Oligonucleotide compositions and methods of use thereof
JP2022519019A5 (https=)
IL316808A (en) Modified double-stranded RNA materials and their uses
WO2023049475A1 (en) Oligonucleotide compositions and methods thereof
JPH05505101A (ja) オリゴヌクレオチド療法における三重らせん形成
RU2006126643A (ru) Олигомерные соединения для модуляции bcl-2
KR20260007576A (ko) 변형된 가이드 rna
JP2024504503A5 (https=)
JP2007529224A5 (https=)
JP2023500661A5 (https=)
JPH06506603A (ja) 一本鎖環状オリゴヌクレオチド
CN115698288A (zh) 核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途
JP2024525800A5 (https=)
JP2024504504A5 (https=)
AU2022352668A1 (en) Double stranded oligonucleotide compositions and methods relating thereto
CN115702006A (zh) 缀合基团及其缀合物
Kalra et al. Conformationally controlled high-affinity targeting of RNA or DNA by novel 2′-amino-DNA/LNA mixmers and pyrenyl-functionalized 2′-amino-DNA
WO2023220744A3 (en) Single-stranded loop oligonucleotides
JPH10504022A (ja) 相補的dna及びトキシン
JP2024513972A5 (https=)
JP2023528755A5 (https=)