JP2024501287A5 - - Google Patents

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Publication number
JP2024501287A5
JP2024501287A5 JP2023538735A JP2023538735A JP2024501287A5 JP 2024501287 A5 JP2024501287 A5 JP 2024501287A5 JP 2023538735 A JP2023538735 A JP 2023538735A JP 2023538735 A JP2023538735 A JP 2023538735A JP 2024501287 A5 JP2024501287 A5 JP 2024501287A5
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JP
Japan
Prior art keywords
cells
particles
gene
composition
gene element
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023538735A
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English (en)
Japanese (ja)
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JP2024501287A (ja
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Application filed filed Critical
Priority claimed from PCT/US2021/064887 external-priority patent/WO2022140560A1/en
Publication of JP2024501287A publication Critical patent/JP2024501287A/ja
Publication of JP2024501287A5 publication Critical patent/JP2024501287A5/ja
Pending legal-status Critical Current

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JP2023538735A 2020-12-23 2021-12-22 RNAを閉じ込めたアネロウイルス(Anellovirus)キャプシドのインビトロアセンブリ Pending JP2024501287A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063130360P 2020-12-23 2020-12-23
US63/130,360 2020-12-23
US202163147064P 2021-02-08 2021-02-08
US63/147,064 2021-02-08
PCT/US2021/064887 WO2022140560A1 (en) 2020-12-23 2021-12-22 In vitro assembly of anellovirus capsids enclosing rna

Publications (2)

Publication Number Publication Date
JP2024501287A JP2024501287A (ja) 2024-01-11
JP2024501287A5 true JP2024501287A5 (https=) 2025-01-07

Family

ID=82160089

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023538735A Pending JP2024501287A (ja) 2020-12-23 2021-12-22 RNAを閉じ込めたアネロウイルス(Anellovirus)キャプシドのインビトロアセンブリ

Country Status (11)

Country Link
US (2) US20220372519A1 (https=)
EP (1) EP4267157A4 (https=)
JP (1) JP2024501287A (https=)
KR (1) KR20230124682A (https=)
AU (1) AU2021409952A1 (https=)
BR (1) BR112023012460A2 (https=)
CA (1) CA3206361A1 (https=)
IL (1) IL303892A (https=)
MX (1) MX2023007643A (https=)
TW (1) TW202235622A (https=)
WO (1) WO2022140560A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240114778A (ko) * 2021-12-15 2024-07-24 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 표면이 변형된 바이러스 입자 및 모듈형 바이러스 입자
WO2025007075A1 (en) * 2023-06-29 2025-01-02 Life Technologies Corporation Molecules resistant to nuclease digestion

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0931158A1 (en) 1996-09-06 1999-07-28 The Trustees Of The University Of Pennsylvania An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
CA2559955C (en) 2004-03-15 2016-02-16 City Of Hope Methods and compositions for the specific inhibition of gene expression by double-stranded rna
KR101728655B1 (ko) 2008-12-18 2017-04-19 다이서나 파마수이티컬, 인크. 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법
US20100249214A1 (en) 2009-02-11 2010-09-30 Dicerna Pharmaceuticals Multiplex dicer substrate rna interference molecules having joining sequences
US9228242B2 (en) * 2009-08-21 2016-01-05 Virginia Tech Intellectual Properties, Inc. Porcine torque teno virus vaccines and diagnosis
EP2653562A1 (en) * 2012-04-20 2013-10-23 Institut Pasteur Anellovirus genome quantification as a biomarker of immune suppression
AU2013266968B2 (en) 2012-05-25 2017-06-29 Emmanuelle CHARPENTIER Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
AU2013335451C1 (en) 2012-10-23 2024-07-04 Toolgen Incorporated Composition for cleaving a target DNA comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein, and use thereof
US20140310830A1 (en) 2012-12-12 2014-10-16 Feng Zhang CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes
EP2840140B2 (en) 2012-12-12 2023-02-22 The Broad Institute, Inc. Crispr-Cas based method for mutation of prokaryotic cells
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
IL239344B2 (en) 2012-12-12 2024-06-01 Broad Inst Inc Systems engineering, methods and optimal guiding components for sequence manipulation
CN113355357B (zh) 2012-12-12 2024-12-03 布罗德研究所有限公司 对用于序列操纵的改进的系统、方法和酶组合物进行的工程化和优化
WO2014093655A2 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
US9790490B2 (en) 2015-06-18 2017-10-17 The Broad Institute Inc. CRISPR enzymes and systems
IL271275B1 (en) * 2017-06-13 2026-04-01 Flagship Pioneering Innovations V Inc Preparations containing croons and their uses
CN111819185A (zh) 2017-12-15 2020-10-23 旗舰创业创新第六有限责任公司 包含环状多核糖核苷酸的组合物及其用途
MX2021006977A (es) * 2018-12-12 2021-10-13 Flagship Pioneering Innovations V Inc Anellosomas y metodos de uso.
CA3119814A1 (en) * 2018-12-12 2020-06-18 Flagship Pioneering Innovations V, Inc. Anellosomes for delivering protein replacement therapeutic modalities
US11166996B2 (en) * 2018-12-12 2021-11-09 Flagship Pioneering Innovations V, Inc. Anellovirus compositions and methods of use
KR20230036109A (ko) * 2020-06-12 2023-03-14 플래그쉽 파이어니어링 이노베이션스 브이, 인크. 바큘로바이러스 발현 시스템
MX2022016475A (es) * 2020-06-17 2023-04-11 Flagship Pioneering Innovations V Inc Metodos de identificacion y caracterizacion de anellovirus y usos de los mismos.

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