JP2024500922A5 - - Google Patents

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Publication number
JP2024500922A5
JP2024500922A5 JP2023538682A JP2023538682A JP2024500922A5 JP 2024500922 A5 JP2024500922 A5 JP 2024500922A5 JP 2023538682 A JP2023538682 A JP 2023538682A JP 2023538682 A JP2023538682 A JP 2023538682A JP 2024500922 A5 JP2024500922 A5 JP 2024500922A5
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JP
Japan
Prior art keywords
cell lymphoma
lymphoma
disease
substituted
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023538682A
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English (en)
Japanese (ja)
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JP2024500922A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/087312 external-priority patent/WO2022136555A1/en
Publication of JP2024500922A publication Critical patent/JP2024500922A/ja
Publication of JP2024500922A5 publication Critical patent/JP2024500922A5/ja
Pending legal-status Critical Current

Links

JP2023538682A 2020-12-23 2021-12-22 改善されたcd30ターゲティング抗体薬物コンジュゲートおよびその使用法 Pending JP2024500922A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20216838 2020-12-23
EP20216838.1 2020-12-23
PCT/EP2021/087312 WO2022136555A1 (en) 2020-12-23 2021-12-22 Improved cd30 targeting antibody drug conjugates and uses thereof

Publications (2)

Publication Number Publication Date
JP2024500922A JP2024500922A (ja) 2024-01-10
JP2024500922A5 true JP2024500922A5 (https=) 2024-12-25

Family

ID=73856997

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023538682A Pending JP2024500922A (ja) 2020-12-23 2021-12-22 改善されたcd30ターゲティング抗体薬物コンジュゲートおよびその使用法

Country Status (13)

Country Link
US (1) US20220193251A1 (https=)
EP (1) EP4267193A1 (https=)
JP (1) JP2024500922A (https=)
KR (1) KR20230124684A (https=)
CN (1) CN117642185A (https=)
AR (1) AR124475A1 (https=)
AU (1) AU2021406518A1 (https=)
CA (1) CA3201178A1 (https=)
IL (1) IL303447A (https=)
MX (1) MX2023007126A (https=)
TW (1) TW202237166A (https=)
UY (1) UY39587A (https=)
WO (1) WO2022136555A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119708088A (zh) * 2023-09-28 2025-03-28 上海糖岭生物医药有限责任公司 二糖-酰腙或二糖-酰肼连接子、基于其的糖工程抗体及糖链定点抗体-药物偶联物及用途
CN117843513B (zh) * 2024-03-07 2024-05-28 深圳创元生物医药科技有限公司 一种(S)-3-Carboxytyrosine的制备方法
WO2025213130A1 (en) * 2024-04-04 2025-10-09 Yale University Antibody drug conjugates

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US633410A (en) 1898-09-22 1899-09-19 George A Ames Ice-cutter.
US5208020A (en) 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
DK1545613T3 (da) 2002-07-31 2011-11-14 Seattle Genetics Inc Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom
NZ610239A (en) 2008-04-30 2014-11-28 Immunogen Inc Cross-linkers and their uses
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt拮抗劑及治療和篩選方法
US10668162B2 (en) 2012-01-06 2020-06-02 Linxis B.V. Method for preparing cell targeting conjugates, and the complexes obtained
US9504756B2 (en) 2012-05-15 2016-11-29 Seattle Genetics, Inc. Self-stabilizing linker conjugates
CN104640572B (zh) 2012-05-15 2018-04-27 索伦托医疗有限公司 药物偶联物,偶联方法,及其用途
PL2991683T3 (pl) 2013-05-02 2020-03-31 Glykos Finland Oy Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem
WO2015057063A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
WO2015057066A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
NZ758049A (en) 2013-10-15 2024-03-22 Seagen Inc Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics
KR102442906B1 (ko) 2013-12-19 2022-09-14 씨젠 인크. 표적화된-약물 컨쥬게이트와 함께 사용되는 메틸렌 카바메이트 링커
EP3160513B1 (en) 2014-06-30 2020-02-12 Glykos Finland Oy Saccharide derivative of a toxic payload and antibody conjugates thereof
CN107106701B (zh) 2014-10-03 2020-11-06 西纳福克斯股份有限公司 磺酰胺接头、其缀合物及制备方法
CA2964837C (en) 2014-10-29 2023-10-17 Ludwig-Maximilians-Universitaet Muenchen Means and methods for site-specific functionalization of polypeptides
EP3378123A4 (en) * 2015-11-17 2019-06-19 Gapwaves AB SELF-EMBOSSED SURFACE MOUNTABLE BOWTIE ANTENNA ASSEMBLY, ANTENNA SHEET AND MANUFACTURING METHOD
JP2017197512A (ja) * 2016-02-08 2017-11-02 シンアフィックス ビー.ブイ. Cd30腫瘍を標的化するための改善された治療指数を有する新規な抗体−コンジュゲート及び抗体−コンジュゲートの治療指数を改善するための方法
EP3413915A1 (en) * 2016-02-08 2018-12-19 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting her2 tumours and method for improving therapeutic index of antibody-conjugates
WO2017186855A1 (en) * 2016-04-28 2017-11-02 Forschungsverbund Berlin E.V. Unusual substrates of tubulin tyrosine ligase
WO2018167847A1 (ja) * 2017-03-14 2018-09-20 株式会社島津製作所 モノクローナル抗体の同時定量方法
GB201820864D0 (en) * 2018-12-20 2019-02-06 J A Kemp Antibody-drug conjugates

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