JP2024156682A5 - - Google Patents
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- JP2024156682A5 JP2024156682A5 JP2024110688A JP2024110688A JP2024156682A5 JP 2024156682 A5 JP2024156682 A5 JP 2024156682A5 JP 2024110688 A JP2024110688 A JP 2024110688A JP 2024110688 A JP2024110688 A JP 2024110688A JP 2024156682 A5 JP2024156682 A5 JP 2024156682A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- antibody
- composition according
- seq
- cell receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 108091008874 T cell receptors Proteins 0.000 claims 6
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 208000003174 Brain Neoplasms Diseases 0.000 claims 3
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 102100020793 Interleukin-13 receptor subunit alpha-2 Human genes 0.000 claims 2
- 101710112634 Interleukin-13 receptor subunit alpha-2 Proteins 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 238000011260 co-administration Methods 0.000 claims 2
- 230000002519 immonomodulatory effect Effects 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 206010003571 Astrocytoma Diseases 0.000 claims 1
- 206010006143 Brain stem glioma Diseases 0.000 claims 1
- 206010014967 Ependymoma Diseases 0.000 claims 1
- 108010055196 EphA2 Receptor Proteins 0.000 claims 1
- 208000032612 Glial tumor Diseases 0.000 claims 1
- 206010018338 Glioma Diseases 0.000 claims 1
- 101000831496 Homo sapiens Toll-like receptor 3 Proteins 0.000 claims 1
- 208000000172 Medulloblastoma Diseases 0.000 claims 1
- 201000010133 Oligodendroglioma Diseases 0.000 claims 1
- 108010002687 Survivin Proteins 0.000 claims 1
- 102000002689 Toll-like receptor Human genes 0.000 claims 1
- 108020000411 Toll-like receptor Proteins 0.000 claims 1
- 229940123384 Toll-like receptor (TLR) agonist Drugs 0.000 claims 1
- 102100024324 Toll-like receptor 3 Human genes 0.000 claims 1
- 208000014070 Vestibular schwannoma Diseases 0.000 claims 1
- 208000004064 acoustic neuroma Diseases 0.000 claims 1
- 229960000397 bevacizumab Drugs 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 206010027191 meningioma Diseases 0.000 claims 1
- 201000010225 mixed cell type cancer Diseases 0.000 claims 1
- 208000029638 mixed neoplasm Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- 210000004498 neuroglial cell Anatomy 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 229960000814 tetanus toxoid Drugs 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261647615P | 2012-05-16 | 2012-05-16 | |
| US61/647,615 | 2012-05-16 | ||
| JP2020065482A JP2020117519A (ja) | 2012-05-16 | 2020-04-01 | 癌幹細胞を標的とした癌ワクチン |
| JP2022104015A JP2022130585A (ja) | 2012-05-16 | 2022-06-28 | 癌幹細胞を標的とした癌ワクチン |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022104015A Division JP2022130585A (ja) | 2012-05-16 | 2022-06-28 | 癌幹細胞を標的とした癌ワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024156682A JP2024156682A (ja) | 2024-11-06 |
| JP2024156682A5 true JP2024156682A5 (https=) | 2024-12-23 |
Family
ID=49584234
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512776A Withdrawn JP2015518835A (ja) | 2012-05-16 | 2013-05-15 | 癌幹細胞を標的とした癌ワクチン |
| JP2018008606A Pending JP2018109004A (ja) | 2012-05-16 | 2018-01-23 | 癌幹細胞を標的とした癌ワクチン |
| JP2020065482A Pending JP2020117519A (ja) | 2012-05-16 | 2020-04-01 | 癌幹細胞を標的とした癌ワクチン |
| JP2022104015A Pending JP2022130585A (ja) | 2012-05-16 | 2022-06-28 | 癌幹細胞を標的とした癌ワクチン |
| JP2024110688A Pending JP2024156682A (ja) | 2012-05-16 | 2024-07-10 | 癌幹細胞を標的とした癌ワクチン |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512776A Withdrawn JP2015518835A (ja) | 2012-05-16 | 2013-05-15 | 癌幹細胞を標的とした癌ワクチン |
| JP2018008606A Pending JP2018109004A (ja) | 2012-05-16 | 2018-01-23 | 癌幹細胞を標的とした癌ワクチン |
| JP2020065482A Pending JP2020117519A (ja) | 2012-05-16 | 2020-04-01 | 癌幹細胞を標的とした癌ワクチン |
| JP2022104015A Pending JP2022130585A (ja) | 2012-05-16 | 2022-06-28 | 癌幹細胞を標的とした癌ワクチン |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US10485858B2 (https=) |
| EP (4) | EP3536334B1 (https=) |
| JP (5) | JP2015518835A (https=) |
| CA (2) | CA3183703A1 (https=) |
| CY (1) | CY1124512T1 (https=) |
| DK (1) | DK3536334T3 (https=) |
| ES (2) | ES2967342T3 (https=) |
| HR (1) | HRP20211432T1 (https=) |
| HU (1) | HUE056350T2 (https=) |
| LT (1) | LT3536334T (https=) |
| PL (1) | PL3536334T3 (https=) |
| PT (1) | PT3536334T (https=) |
| RS (1) | RS62406B1 (https=) |
| SI (1) | SI3536334T1 (https=) |
| SM (1) | SMT202100545T1 (https=) |
| WO (1) | WO2013173411A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3183703A1 (en) | 2012-05-16 | 2013-11-21 | Stemline Therapeutics, Inc. | Cancer stem cell targeted cancer vaccines |
| WO2018065623A2 (en) | 2016-10-07 | 2018-04-12 | Enterome | Immunogenic compounds for cancer therapy |
| CN110022894B (zh) | 2016-10-07 | 2024-01-19 | 恩特罗姆公司 | 用于癌症疗法的免疫原性化合物 |
| WO2018065628A2 (en) | 2016-10-07 | 2018-04-12 | Enterome | Microbiota sequence variants of tumor-related antigenic epitopes |
| US20210106652A1 (en) * | 2018-04-11 | 2021-04-15 | Enterome S.A. | Immunogenic Compounds For Treatment Of Fibrosis, Autoimmune Diseases And Inflammation |
| HRP20230007T1 (hr) * | 2018-04-11 | 2023-03-03 | Enterome S.A. | Antigenski peptidi, namijenjeni sprječavanju i liječenju raka |
| CN115605595A (zh) * | 2020-02-05 | 2023-01-13 | 瓦克斯恩有限公司（Ae） | 生存素与gm-csf的融合体、编码dna、重组表达载体、抗肿瘤疫苗及其应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| DE4121547A1 (de) | 1991-06-28 | 1993-01-14 | Daimler Benz Ag | Mehrschichtisolierfolie |
| US6419931B1 (en) | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
| US6162432A (en) | 1991-10-07 | 2000-12-19 | Biogen, Inc. | Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction |
| ATE161190T1 (de) | 1991-10-07 | 1998-01-15 | Biogen Inc | Vorbeugungsmethode oder behandlung von, durch antigen-präsentierende zellen hervorgerufene, hautkrankheiten mittels inhibitoren der cd2/lfa-3 wechselwirkung |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| WO1996018409A1 (en) | 1994-12-14 | 1996-06-20 | The Scripps Research Institute | In vivo activation of tumor-specific cytotoxic t cells |
| US5837231A (en) * | 1996-06-27 | 1998-11-17 | Regents Of The University Of Minnesota | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
| WO2001058479A1 (en) | 2000-02-08 | 2001-08-16 | The Penn State Research Foundation | Immunotherapy using interleukin 13 receptor subunit alpha 2 |
| CA2671940A1 (en) | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Identification of partial agonists of the a2a adenosine receptor |
| AU2002250236A1 (en) | 2001-03-02 | 2002-09-19 | Medimmune, Inc. | Cd2 antagonists for treatment of autoimmune or inflammatory disease |
| CA2439852A1 (en) | 2001-03-02 | 2002-09-12 | Christine Dingivan | Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphav beta3 antagonists |
| FR2838742B1 (fr) | 2002-04-23 | 2004-07-09 | Inst Nat Sante Rech Med | Epitopes t de l'antigene epha2 |
| WO2004087758A2 (en) | 2003-03-26 | 2004-10-14 | Neopharm, Inc. | Il 13 receptor alpha 2 antibody and methods of use |
| AU2004229501B2 (en) | 2003-04-11 | 2011-08-18 | Medimmune, Llc | Recombinant IL-9 antibodies and uses thereof |
| JP2004353820A (ja) | 2003-05-30 | 2004-12-16 | Toyota Motor Corp | トリポート型等速ジョイント部品およびトリポート型等速ジョイント |
| EP1651671A2 (en) | 2003-07-30 | 2006-05-03 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Epha2 t-cell epitope agonists and uses therefor |
| EP1682173A4 (en) | 2003-10-15 | 2007-10-31 | Medimmune Inc | EPHA2 VACCINE ON LISTERIA BASE |
| WO2005049073A2 (en) | 2003-11-19 | 2005-06-02 | Survac Aps | Proteins belonging to the bcl-2 family and fragments thereof, and their use in cancer patients |
| US20050153923A1 (en) | 2003-12-04 | 2005-07-14 | Kinch Michael S. | Targeted drug delivery using EphA2 or EphA4 binding moieties |
| US7612162B2 (en) | 2004-09-21 | 2009-11-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Peptide analogs capable of enhancing stimulation of a glioma-specific CTL response |
| ES2534752T3 (es) | 2004-12-07 | 2015-04-27 | Toray Industries, Inc. | Nuevo péptido antigénico contra el cáncer y utilización del mismo |
| ES2523172T3 (es) * | 2005-02-04 | 2014-11-21 | Survac Aps | Vacuna de péptido de survivina |
| US20070104689A1 (en) * | 2005-09-27 | 2007-05-10 | Merck Patent Gmbh | Compositions and methods for treating tumors presenting survivin antigens |
| CA2628255C (en) | 2005-10-31 | 2016-04-19 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US8343461B2 (en) | 2006-03-08 | 2013-01-01 | Wake Forest University Health Sciences | Molecular signature of cancer |
| ES2536426T3 (es) | 2006-03-23 | 2015-05-25 | Novartis Ag | Compuestos de imidazoquinoxalina como inmunomoduladores |
| US8063063B2 (en) | 2006-03-23 | 2011-11-22 | Novartis Ag | Immunopotentiating compounds |
| CA2698597A1 (en) | 2006-09-07 | 2008-03-13 | Stemline Therapeutics, Inc. | Monitoring cancer stem cells |
| US20080118518A1 (en) | 2006-09-07 | 2008-05-22 | Cirrito Thomas P | Cancer stem cell-targeted cancer therapy |
| CA2700436C (en) | 2006-09-28 | 2017-04-18 | John S. Yu | Cancer vaccines and vaccination methods |
| CA2675521C (en) | 2007-01-22 | 2016-04-26 | Raven Biotechnologies | Human cancer stem cells |
| CN101754768B (zh) | 2007-07-19 | 2013-07-10 | 健康研究股份有限公司 | 用作癌症疫苗的存活蛋白肽 |
| RS53782B1 (sr) * | 2008-10-01 | 2015-06-30 | Immatics Biotechnologies Gmbh | Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera |
| WO2011100754A1 (en) | 2010-02-15 | 2011-08-18 | The Trustees Of The University Of Pennsylvania | Live listeria-based vaccines for central nervous system therapy |
| GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| CA2809362C (en) | 2010-08-24 | 2020-03-10 | University Of Pittsburgh - Of The Commonwealth System Of Higher Educatn | Interleukin-13 receptor alpha 2 peptide-based brain cancer vaccines |
| US8801711B2 (en) * | 2011-06-16 | 2014-08-12 | Clifford T. Solomon | Skull clamp system with pressure limiting and alarm systems |
| CA3183703A1 (en) | 2012-05-16 | 2013-11-21 | Stemline Therapeutics, Inc. | Cancer stem cell targeted cancer vaccines |
-
2013
- 2013-05-15 CA CA3183703A patent/CA3183703A1/en active Pending
- 2013-05-15 SI SI201331930T patent/SI3536334T1/sl unknown
- 2013-05-15 EP EP18213178.9A patent/EP3536334B1/en active Active
- 2013-05-15 EP EP23193214.6A patent/EP4321218A3/en active Pending
- 2013-05-15 PT PT182131789T patent/PT3536334T/pt unknown
- 2013-05-15 HU HUE18213178A patent/HUE056350T2/hu unknown
- 2013-05-15 ES ES21162077T patent/ES2967342T3/es active Active
- 2013-05-15 LT LTEP18213178.9T patent/LT3536334T/lt unknown
- 2013-05-15 EP EP13790444.7A patent/EP2849772A4/en not_active Ceased
- 2013-05-15 US US14/401,053 patent/US10485858B2/en active Active
- 2013-05-15 PL PL18213178T patent/PL3536334T3/pl unknown
- 2013-05-15 DK DK18213178.9T patent/DK3536334T3/da active
- 2013-05-15 EP EP21162077.8A patent/EP3912634B1/en active Active
- 2013-05-15 JP JP2015512776A patent/JP2015518835A/ja not_active Withdrawn
- 2013-05-15 RS RS20211149A patent/RS62406B1/sr unknown
- 2013-05-15 SM SM20210545T patent/SMT202100545T1/it unknown
- 2013-05-15 WO PCT/US2013/041063 patent/WO2013173411A1/en not_active Ceased
- 2013-05-15 CA CA2911191A patent/CA2911191C/en active Active
- 2013-05-15 ES ES18213178T patent/ES2890529T3/es active Active
-
2018
- 2018-01-23 JP JP2018008606A patent/JP2018109004A/ja active Pending
-
2019
- 2019-10-10 US US16/599,031 patent/US11672847B2/en active Active
-
2020
- 2020-04-01 JP JP2020065482A patent/JP2020117519A/ja active Pending
-
2021
- 2021-09-13 HR HRP20211432TT patent/HRP20211432T1/hr unknown
- 2021-09-21 CY CY20211100828T patent/CY1124512T1/el unknown
-
2022
- 2022-06-28 JP JP2022104015A patent/JP2022130585A/ja active Pending
-
2023
- 2023-04-28 US US18/308,774 patent/US12357678B2/en active Active
-
2024
- 2024-07-10 JP JP2024110688A patent/JP2024156682A/ja active Pending
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