JP2024153768A5 - - Google Patents
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- JP2024153768A5 JP2024153768A5 JP2024121246A JP2024121246A JP2024153768A5 JP 2024153768 A5 JP2024153768 A5 JP 2024153768A5 JP 2024121246 A JP2024121246 A JP 2024121246A JP 2024121246 A JP2024121246 A JP 2024121246A JP 2024153768 A5 JP2024153768 A5 JP 2024153768A5
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- JP
- Japan
- Prior art keywords
- cells
- amount
- day
- factor
- pharyngeal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962827383P | 2019-04-01 | 2019-04-01 | |
| US62/827,383 | 2019-04-01 | ||
| JP2021558816A JP7740706B2 (ja) | 2019-04-01 | 2020-03-31 | 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 |
| PCT/US2020/025955 WO2020205859A1 (en) | 2019-04-01 | 2020-03-31 | Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021558816A Division JP7740706B2 (ja) | 2019-04-01 | 2020-03-31 | 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024153768A JP2024153768A (ja) | 2024-10-29 |
| JP2024153768A5 true JP2024153768A5 (https=) | 2025-01-09 |
Family
ID=72667458
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021558816A Active JP7740706B2 (ja) | 2019-04-01 | 2020-03-31 | 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 |
| JP2024121246A Pending JP2024153768A (ja) | 2019-04-01 | 2024-07-26 | 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021558816A Active JP7740706B2 (ja) | 2019-04-01 | 2020-03-31 | 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220127569A1 (https=) |
| EP (1) | EP3947639A4 (https=) |
| JP (2) | JP7740706B2 (https=) |
| KR (1) | KR20210146297A (https=) |
| CN (2) | CN119351306A (https=) |
| AU (1) | AU2020253429A1 (https=) |
| CA (1) | CA3135377A1 (https=) |
| IL (1) | IL286936A (https=) |
| MX (1) | MX2021012041A (https=) |
| SG (1) | SG11202109279PA (https=) |
| WO (1) | WO2020205859A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4142754A4 (en) * | 2020-04-28 | 2024-06-12 | The Regents Of The University Of California | METHODS FOR IN VITRO GENERATION OF THYMIC CELLS |
| EP4277977A4 (en) * | 2021-01-15 | 2025-02-12 | The Board of Trustees of the Leland Stanford Junior University | PRODUCTION OF INDUCED HUMAN THYMIC EPITHELIAL CELLS AND THEIR APPLICATION IN CELL-BASED IMMUNOTHERAPIES |
| CN113215081B (zh) * | 2021-06-01 | 2023-04-14 | 华中科技大学同济医学院附属同济医院 | 诱导干细胞分化为甲状旁腺细胞的方法及其组合物 |
| WO2023064457A1 (en) * | 2021-10-15 | 2023-04-20 | Thymmune Therapeutics, Inc. | Thymic cells and methods of making |
| EP4293110A1 (en) | 2022-06-17 | 2023-12-20 | Nantes Université | Process for obtaining functional lymphocytes cells |
| WO2025136749A1 (en) * | 2023-12-19 | 2025-06-26 | The Board Of Trustees Of The Leland Stanford Junior University | Thymic epithelial cells and methods of producing and using the same |
| CN119614476A (zh) * | 2024-11-13 | 2025-03-14 | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 胸腺类器官的构建方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040096971A1 (en) * | 2000-12-22 | 2004-05-20 | Blackburn Catherine Clare | Thymic epithelial progenitor cells and uses thereof |
| WO2010143529A1 (ja) * | 2009-06-09 | 2010-12-16 | 国立大学法人名古屋大学 | 多能性幹細胞を胸腺上皮へ分化誘導する方法 |
| EP2563908B1 (en) * | 2010-04-25 | 2019-01-09 | Icahn School of Medicine at Mount Sinai | Generation of anterior foregut endoderm from pluripotent cells |
| CN102732479B (zh) * | 2011-03-31 | 2014-08-27 | 北京大学 | 胸腺上皮前体细胞的制备方法及其专用培养基 |
| US9657273B2 (en) * | 2012-10-12 | 2017-05-23 | Industry-University Cooperation Foundation Sogang University | Method for suppressing teratoma formation via selective cell death induction in undifferentiated human-induced pluripotent stem cells |
| WO2014134213A1 (en) * | 2013-02-27 | 2014-09-04 | The Regents Of The University Of California | Generation of thymic epithelial progenitor cells in vitro |
| US11898166B2 (en) | 2017-09-20 | 2024-02-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | In vitro generation of thymic organoid from human pluripotent stem cells |
| KR20220004126A (ko) * | 2019-04-26 | 2022-01-11 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 유도 다능성 줄기 세포로부터 생체내에서 기능적이고 환자-특이적인 흉선 조직의 생성 |
| WO2021108514A1 (en) * | 2019-11-25 | 2021-06-03 | Allegheny Singer Research Institute | Thymus organoids bioengineered form human pluripotent stem cells |
-
2020
- 2020-03-31 WO PCT/US2020/025955 patent/WO2020205859A1/en not_active Ceased
- 2020-03-31 CN CN202411293215.7A patent/CN119351306A/zh active Pending
- 2020-03-31 SG SG11202109279PA patent/SG11202109279PA/en unknown
- 2020-03-31 CN CN202080021893.1A patent/CN113646423B/zh active Active
- 2020-03-31 KR KR1020217029911A patent/KR20210146297A/ko active Pending
- 2020-03-31 AU AU2020253429A patent/AU2020253429A1/en active Pending
- 2020-03-31 MX MX2021012041A patent/MX2021012041A/es unknown
- 2020-03-31 CA CA3135377A patent/CA3135377A1/en active Pending
- 2020-03-31 EP EP20783448.2A patent/EP3947639A4/en active Pending
- 2020-03-31 JP JP2021558816A patent/JP7740706B2/ja active Active
-
2021
- 2021-10-03 IL IL286936A patent/IL286936A/en unknown
-
2022
- 2022-01-12 US US17/492,137 patent/US20220127569A1/en active Pending
-
2024
- 2024-07-26 JP JP2024121246A patent/JP2024153768A/ja active Pending
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