KR20210146297A - 다능성 줄기 세포의 흉선 상피 세포 및 흉선 상피 세포 전구세포 분화를 촉진하는 방법 - Google Patents

다능성 줄기 세포의 흉선 상피 세포 및 흉선 상피 세포 전구세포 분화를 촉진하는 방법 Download PDF

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KR20210146297A
KR20210146297A KR1020217029911A KR20217029911A KR20210146297A KR 20210146297 A KR20210146297 A KR 20210146297A KR 1020217029911 A KR1020217029911 A KR 1020217029911A KR 20217029911 A KR20217029911 A KR 20217029911A KR 20210146297 A KR20210146297 A KR 20210146297A
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cells
cell
days
thymic epithelial
pharyngeal
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페나 라파엘 그라스
메간 사이크스
니콜 댄즐
모흐센 코스라비-마하로에이
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더 트러스티스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕
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KR1020217029911A 2019-04-01 2020-03-31 다능성 줄기 세포의 흉선 상피 세포 및 흉선 상피 세포 전구세포 분화를 촉진하는 방법 Pending KR20210146297A (ko)

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Application Number Priority Date Filing Date Title
US201962827383P 2019-04-01 2019-04-01
US62/827,383 2019-04-01
PCT/US2020/025955 WO2020205859A1 (en) 2019-04-01 2020-03-31 Methods of promoting thymic epithelial cell and thymic epithelial cell progenitor differentiation of pluripotent stem cells

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KR20210146297A true KR20210146297A (ko) 2021-12-03

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US (1) US20220127569A1 (https=)
EP (1) EP3947639A4 (https=)
JP (2) JP7740706B2 (https=)
KR (1) KR20210146297A (https=)
CN (2) CN113646423B (https=)
AU (1) AU2020253429A1 (https=)
CA (1) CA3135377A1 (https=)
IL (1) IL286936A (https=)
MX (1) MX2021012041A (https=)
SG (1) SG11202109279PA (https=)
WO (1) WO2020205859A1 (https=)

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Publication number Priority date Publication date Assignee Title
CA3179236A1 (en) * 2020-04-28 2021-11-04 The Regents Of The University Of California Methods for generating thymic cells in vitro
WO2022155291A1 (en) * 2021-01-15 2022-07-21 The Board Of Trustees Of The Leland Stanford Junior University Generation of induced human thymic epithelial cells and its application in cell-based immunotherapies
CN113215081B (zh) * 2021-06-01 2023-04-14 华中科技大学同济医学院附属同济医院 诱导干细胞分化为甲状旁腺细胞的方法及其组合物
WO2023064457A1 (en) * 2021-10-15 2023-04-20 Thymmune Therapeutics, Inc. Thymic cells and methods of making
EP4293110A1 (en) 2022-06-17 2023-12-20 Nantes Université Process for obtaining functional lymphocytes cells
WO2025136749A1 (en) * 2023-12-19 2025-06-26 The Board Of Trustees Of The Leland Stanford Junior University Thymic epithelial cells and methods of producing and using the same
CN119614476A (zh) * 2024-11-13 2025-03-14 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） 胸腺类器官的构建方法和应用

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Publication number Priority date Publication date Assignee Title
US20040096971A1 (en) * 2000-12-22 2004-05-20 Blackburn Catherine Clare Thymic epithelial progenitor cells and uses thereof
WO2010143529A1 (ja) * 2009-06-09 2010-12-16 国立大学法人名古屋大学 多能性幹細胞を胸腺上皮へ分化誘導する方法
EP2563908B1 (en) * 2010-04-25 2019-01-09 Icahn School of Medicine at Mount Sinai Generation of anterior foregut endoderm from pluripotent cells
CN102732479B (zh) * 2011-03-31 2014-08-27 北京大学 胸腺上皮前体细胞的制备方法及其专用培养基
WO2014058274A1 (ko) * 2012-10-12 2014-04-17 서강대학교 산학협력단 미분화 인간 유도만능줄기세포의 선택적 세포사멸 유도를 통한 테라토마 형성 억제 방법
CA2902857C (en) * 2013-02-27 2022-11-29 The Regents Of The University Of California Generation of thymic epithelial progenitor cells in vitro
US11898166B2 (en) 2017-09-20 2024-02-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services In vitro generation of thymic organoid from human pluripotent stem cells
WO2020220040A1 (en) * 2019-04-26 2020-10-29 The Regents Of The University Of Colorado, A Body Corporate Generation of functional and patient-specific thymic tissue in vivo from induced pluripotent stem cells
KR20220113720A (ko) * 2019-11-25 2022-08-16 앨리게니 싱어 리서치 인스티튜트 인간 전분화능 줄기 세포로부터 생체공학적으로 조작된 흉선 오가노이드

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JP7740706B2 (ja) 2025-09-17
IL286936A (en) 2021-10-31
EP3947639A4 (en) 2023-01-25
JP2022527338A (ja) 2022-06-01
US20220127569A1 (en) 2022-04-28
CN113646423B (zh) 2024-10-01
EP3947639A1 (en) 2022-02-09
MX2021012041A (es) 2021-11-03
AU2020253429A1 (en) 2021-09-09
CN113646423A (zh) 2021-11-12
WO2020205859A1 (en) 2020-10-08
SG11202109279PA (en) 2021-09-29
CA3135377A1 (en) 2020-10-08
CN119351306A (zh) 2025-01-24
JP2024153768A (ja) 2024-10-29

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