JP2024059888A5 - - Google Patents
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- Publication number
- JP2024059888A5 JP2024059888A5 JP2024028517A JP2024028517A JP2024059888A5 JP 2024059888 A5 JP2024059888 A5 JP 2024059888A5 JP 2024028517 A JP2024028517 A JP 2024028517A JP 2024028517 A JP2024028517 A JP 2024028517A JP 2024059888 A5 JP2024059888 A5 JP 2024059888A5
- Authority
- JP
- Japan
- Prior art keywords
- monoclonal antibody
- monomeric
- cell culture
- chromatography
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862649976P | 2018-03-29 | 2018-03-29 | |
| US62/649,976 | 2018-03-29 | ||
| JP2020552186A JP2021519752A (ja) | 2018-03-29 | 2019-03-28 | 単量体モノクローナル抗体を精製する方法 |
| PCT/US2019/024565 WO2019191416A1 (en) | 2018-03-29 | 2019-03-28 | Methods of purifying monomeric monoclonal antibodies |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552186A Division JP2021519752A (ja) | 2018-03-29 | 2019-03-28 | 単量体モノクローナル抗体を精製する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024059888A JP2024059888A (ja) | 2024-05-01 |
| JP2024059888A5 true JP2024059888A5 (enExample) | 2024-11-12 |
Family
ID=66286977
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552186A Pending JP2021519752A (ja) | 2018-03-29 | 2019-03-28 | 単量体モノクローナル抗体を精製する方法 |
| JP2024028517A Pending JP2024059888A (ja) | 2018-03-29 | 2024-02-28 | 単量体モノクローナル抗体を精製する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552186A Pending JP2021519752A (ja) | 2018-03-29 | 2019-03-28 | 単量体モノクローナル抗体を精製する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20210009632A1 (enExample) |
| EP (1) | EP3774882A1 (enExample) |
| JP (2) | JP2021519752A (enExample) |
| KR (1) | KR20200136464A (enExample) |
| CN (1) | CN112313248A (enExample) |
| WO (1) | WO2019191416A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201628649A (zh) | 2014-10-09 | 2016-08-16 | 再生元醫藥公司 | 減少醫藥調配物中微可見顆粒之方法 |
| KR20230041834A (ko) | 2016-08-16 | 2023-03-24 | 리제너론 파아마슈티컬스, 인크. | 혼합물로부터 개별 항체들을 정량하는 방법 |
| CN119492842A (zh) | 2016-10-25 | 2025-02-21 | 里珍纳龙药品有限公司 | 用于色谱数据分析的方法和系统 |
| CN118416215A (zh) | 2017-09-19 | 2024-08-02 | 里珍纳龙药品有限公司 | 减少粒子形成的方法以及由其形成的组合物 |
| TWI853823B (zh) | 2018-07-02 | 2024-09-01 | 美商里珍納龍藥品有限公司 | 自混合物製備多肽之系統及方法 |
| EP3934620A1 (en) | 2019-03-05 | 2022-01-12 | Regeneron Pharmaceuticals, Inc. | Human serum albumin in formulations |
| CN114981286B (zh) | 2019-05-03 | 2026-02-13 | 豪夫迈·罗氏有限公司 | 降低从纯化平台获得的组合物中酶水解活性速率的方法 |
| EP4090666A1 (en) | 2020-01-15 | 2022-11-23 | F. Hoffmann-La Roche AG | Methods to decrease impurities from recombinant protein manufacturing processes |
| US20240262928A1 (en) * | 2020-03-27 | 2024-08-08 | Haemalogix Pty Ltd | Composition and Method |
| AU2021371309A1 (en) * | 2020-10-30 | 2023-05-18 | Genentech, Inc. | Purification platforms for obtaining pharmaceutical compositions having a reduced hydrolytic enzyme activity rate |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5476996A (en) | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| AU8507191A (en) | 1990-08-29 | 1992-03-30 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| PT1696031E (pt) | 1991-12-02 | 2010-06-25 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| AU3328493A (en) | 1991-12-17 | 1993-07-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69303494T2 (de) | 1992-11-13 | 1997-01-16 | Idec Pharma Corp | Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma |
| AU6819494A (en) | 1993-04-26 | 1994-11-21 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5534615A (en) | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
| CN102766210B (zh) | 1999-08-24 | 2015-07-08 | E.R.施贵宝&圣斯有限责任公司 | 人ctla-4抗体及其应用 |
| IL155977A0 (en) | 2000-11-30 | 2003-12-23 | Medarex Inc | Transgenic transchromosomal rodents for making human antibodies |
| WO2005060457A2 (en) * | 2003-12-04 | 2005-07-07 | Pdl Biopharma, Inc. | Treatment of inflammatory bowel diseases with anti-ip-10 antibodies |
| CN105315323A (zh) * | 2007-10-30 | 2016-02-10 | 健泰科生物技术公司 | 通过阳离子交换层析进行的抗体纯化 |
| WO2011037983A1 (en) * | 2009-09-23 | 2011-03-31 | Medarex, Inc. | Cation exchange chromatography |
| US20130178608A1 (en) * | 2009-12-29 | 2013-07-11 | Samir Kulkarni | Protein purification by ion exchange |
| CN106414495A (zh) * | 2014-02-07 | 2017-02-15 | 诺和诺德股份有限公司 | 抗体处理方法 |
| KR102630475B1 (ko) * | 2015-11-30 | 2024-01-26 | 브리스톨-마이어스 스큅 컴퍼니 | 항 인간 ip-10 항체 및 이의 용도 |
| JP2019530646A (ja) * | 2016-08-12 | 2019-10-24 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | タンパク質精製法 |
-
2019
- 2019-03-28 WO PCT/US2019/024565 patent/WO2019191416A1/en not_active Ceased
- 2019-03-28 JP JP2020552186A patent/JP2021519752A/ja active Pending
- 2019-03-28 US US17/042,984 patent/US20210009632A1/en not_active Abandoned
- 2019-03-28 EP EP19719681.9A patent/EP3774882A1/en active Pending
- 2019-03-28 KR KR1020207030734A patent/KR20200136464A/ko not_active Ceased
- 2019-03-28 CN CN201980022886.0A patent/CN112313248A/zh active Pending
-
2024
- 2024-02-28 JP JP2024028517A patent/JP2024059888A/ja active Pending
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