JP2024026104A5 - - Google Patents

Info

Publication number
JP2024026104A5
JP2024026104A5 JP2023195267A JP2023195267A JP2024026104A5 JP 2024026104 A5 JP2024026104 A5 JP 2024026104A5 JP 2023195267 A JP2023195267 A JP 2023195267A JP 2023195267 A JP2023195267 A JP 2023195267A JP 2024026104 A5 JP2024026104 A5 JP 2024026104A5
Authority
JP
Japan
Prior art keywords
neonatal
pharmaceutical composition
pain
convulsions
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023195267A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024026104A (ja
Filing date
Publication date
Priority claimed from PCT/US2019/023039 external-priority patent/WO2019183148A1/en
Application filed filed Critical
Publication of JP2024026104A publication Critical patent/JP2024026104A/ja
Publication of JP2024026104A5 publication Critical patent/JP2024026104A5/ja
Pending legal-status Critical Current

Links

JP2023195267A 2018-03-19 2023-11-16 Kv7チャネル活性化剤の構成および使用方法 Pending JP2024026104A (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201862644932P 2018-03-19 2018-03-19
US201862644902P 2018-03-19 2018-03-19
US62/644,902 2018-03-19
US62/644,932 2018-03-19
US201862663438P 2018-04-27 2018-04-27
US62/663,438 2018-04-27
US201862697198P 2018-07-12 2018-07-12
US62/697,198 2018-07-12
PCT/US2019/023039 WO2019183148A1 (en) 2018-03-19 2019-03-19 Kv7 channel activators compositions and methods of use
JP2020551340A JP7757036B2 (ja) 2018-03-19 2019-03-19 Kv7チャネル活性化剤の構成および使用方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020551340A Division JP7757036B2 (ja) 2018-03-19 2019-03-19 Kv7チャネル活性化剤の構成および使用方法

Publications (2)

Publication Number Publication Date
JP2024026104A JP2024026104A (ja) 2024-02-28
JP2024026104A5 true JP2024026104A5 (enExample) 2026-01-22

Family

ID=67905138

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020551340A Active JP7757036B2 (ja) 2018-03-19 2019-03-19 Kv7チャネル活性化剤の構成および使用方法
JP2023195267A Pending JP2024026104A (ja) 2018-03-19 2023-11-16 Kv7チャネル活性化剤の構成および使用方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020551340A Active JP7757036B2 (ja) 2018-03-19 2019-03-19 Kv7チャネル活性化剤の構成および使用方法

Country Status (13)

Country Link
US (5) US10851067B2 (enExample)
EP (1) EP3768677A4 (enExample)
JP (2) JP7757036B2 (enExample)
KR (3) KR102868652B1 (enExample)
CN (6) CN118955402A (enExample)
AU (3) AU2019239955B2 (enExample)
BR (1) BR112020018933A2 (enExample)
CA (1) CA3093976A1 (enExample)
IL (2) IL277419B2 (enExample)
MX (2) MX2020009693A (enExample)
SG (1) SG11202008030WA (enExample)
WO (1) WO2019183148A1 (enExample)
ZA (1) ZA202308070B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SMT202300362T1 (it) * 2014-09-12 2023-11-13 Biohaven Therapeutics Ltd Benzoimidazol-1,2-il-ammidi come attivatori di canale kv7
SG11202008030WA (en) * 2018-03-19 2020-10-29 Knopp Biosciences Llc Kv7 channel activators compositions and methods of use
BR112022004847A2 (pt) * 2019-09-17 2022-06-07 Knopp Biosciences Llc Método para tratar uma doença ou distúrbio de neurodesenvolvimento
CN120435316A (zh) * 2022-08-30 2025-08-05 拜奥海芬治疗学有限公司 包括金属通道激活剂和nmda受体拮抗剂的组合疗法
EP4584250A4 (en) * 2022-09-06 2026-02-25 Biohaven Therapeutics Ltd POLYTHERAPIES INCLUDING METAL CHANNEL ACTIVATORS
WO2025035066A1 (en) * 2023-08-10 2025-02-13 Biohaven Therapeutics Ltd. Extended-release formulations of kv7.2/7.3 potassium channel activators
AU2024340894A1 (en) * 2023-09-15 2026-04-02 Biohaven Therapeutics Ltd. Methods of treating epilepsy and related disorders with potent and selective potassium channel activators
WO2025103406A1 (zh) * 2023-11-15 2025-05-22 南京明德新药研发有限公司 6并5杂芳基衍生物及其应用
WO2025137661A1 (en) * 2023-12-22 2025-06-26 Biohaven Therapeutics Ltd. Combination treatment of neurological disorders
WO2025198930A1 (en) * 2024-03-18 2025-09-25 Humanwell Pharmacuetical Us, Inc. Small molecules as kcnq2/3 (kv7.2/3) channel activators and their medical use thereof
WO2026042005A1 (en) 2024-08-18 2026-02-26 Biohaven Therapeutics Ltd. Prodrugs of benzimidazol-1,2-yl amide compounds

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0772181B2 (ja) 1989-06-26 1995-08-02 株式会社大塚製薬工場 ベンズイミダゾール誘導体
JPH0772181A (ja) 1993-09-03 1995-03-17 Advantest Corp 電位波形測定方法および装置
GB9413724D0 (en) 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
US6855714B2 (en) 2001-07-06 2005-02-15 Schering Aktiengesellschaft 1-alkyl-2-aryl-benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives
SE0301701D0 (sv) 2003-06-10 2003-06-10 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CA2607219A1 (en) * 2005-05-18 2007-02-15 Neuraxon, Inc. Substituted benzimidazole compounds with dual nos inhibitory activity and mu opioid agonist activity
CN101516873A (zh) * 2006-10-03 2009-08-26 神经研究公司 用作钾通道调节剂的吲唑基衍生物
CN101778833A (zh) 2007-08-10 2010-07-14 日本曹达株式会社 含氮杂环化合物和有害生物防除剂
ES2539714T3 (es) 2007-11-22 2015-07-03 Zenyaku Kogyo Kabushikikaisha Dispersiones sólidas que comprenden un cuerpo amorfo compuesto por un compuesto antitumoral heterocíclico
GB0723794D0 (en) 2007-12-05 2008-01-16 Lectus Therapeutics Ltd Potassium ion channel modulators and uses thereof
AU2008343813B2 (en) 2007-12-19 2012-04-12 Amgen Inc. Inhibitors of PI3 kinase
WO2010051819A1 (en) 2008-11-10 2010-05-14 Neurosearch A/S Novel 2,3-diamino-quinazolinone derivatives and their medical use
WO2010080503A1 (en) 2008-12-19 2010-07-15 Genentech, Inc. Heterocyclic compounds and methods of use
AU2011275393B2 (en) 2010-07-08 2014-04-10 Pfizer Inc. Piperidinyl pyrimidine amides as Kv7 potassium channel openers
SG10201505997TA (en) 2010-08-05 2015-09-29 Amgen Inc Benzimidazole And Azabenzimidazole Compounds That Inhibit Anaplastic Lymphoma Kinase
WO2014145852A2 (en) * 2013-03-15 2014-09-18 Knopp Biosciences Llc Imidazo(4,5-b) pyridin-2-yl amides as kv7 channel activators
US10471139B2 (en) 2013-08-15 2019-11-12 The University Of Kansas Toll-like receptor agonists
SMT202300362T1 (it) 2014-09-12 2023-11-13 Biohaven Therapeutics Ltd Benzoimidazol-1,2-il-ammidi come attivatori di canale kv7
SG11202008030WA (en) * 2018-03-19 2020-10-29 Knopp Biosciences Llc Kv7 channel activators compositions and methods of use
BR112022004847A2 (pt) * 2019-09-17 2022-06-07 Knopp Biosciences Llc Método para tratar uma doença ou distúrbio de neurodesenvolvimento

Similar Documents

Publication Publication Date Title
JP2024026104A5 (enExample)
JP2021518844A5 (enExample)
JP2009509920A5 (enExample)
RU2009147708A (ru) Производные оксадиазола и их применение в качестве потенцирующих средств метаботропных глутаматных рецепторов-842
JP2018104454A5 (enExample)
JP2013519728A5 (enExample)
JP2013544277A5 (enExample)
JP2010523562A5 (enExample)
CN110366555A (zh) 甾族类衍生物调节剂、其制备方法和应用
JP2009530237A5 (enExample)
JP2008044931A5 (enExample)
JP2020506899A5 (enExample)
JP2008533087A5 (enExample)
CA2441565A1 (en) Bisarylamines as potassium channel openers
JP2008546714A5 (enExample)
JP2016155815A5 (enExample)
RU2015137619A (ru) Замещенные нафтиридиновые и хинолиновые соединения как ингибиторы мао
JP2020524679A5 (enExample)
JP2007509043A5 (enExample)
JP2012508275A5 (enExample)
RU2013142364A (ru) Замещенные производные 6,7-диалкокси-3-изохинолинола в качестве ингибиторов фосфодиэстеразы 10 (фдэ10а)
JP2022502405A5 (enExample)
JP2016506939A5 (enExample)
JP2015521643A5 (enExample)
TW200613255A (en) Therapeutic diphenyl ether ligands