JP2024023232A5 - - Google Patents
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- JP2024023232A5 JP2024023232A5 JP2023189072A JP2023189072A JP2024023232A5 JP 2024023232 A5 JP2024023232 A5 JP 2024023232A5 JP 2023189072 A JP2023189072 A JP 2023189072A JP 2023189072 A JP2023189072 A JP 2023189072A JP 2024023232 A5 JP2024023232 A5 JP 2024023232A5
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- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- identity
- nucleic acid
- car
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025184908A JP2026031977A (ja) | 2018-06-04 | 2025-10-31 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862680297P | 2018-06-04 | 2018-06-04 | |
| US62/680,297 | 2018-06-04 | ||
| JP2020567215A JP2021525534A (ja) | 2018-06-04 | 2019-06-04 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
| PCT/US2019/035384 WO2019236577A2 (en) | 2018-06-04 | 2019-06-04 | Muc16 specific chimeric antigen receptors and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567215A Division JP2021525534A (ja) | 2018-06-04 | 2019-06-04 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025184908A Division JP2026031977A (ja) | 2018-06-04 | 2025-10-31 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024023232A JP2024023232A (ja) | 2024-02-21 |
| JP2024023232A5 true JP2024023232A5 (enExample) | 2024-10-16 |
| JP7827673B2 JP7827673B2 (ja) | 2026-03-10 |
Family
ID=68764543
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567215A Pending JP2021525534A (ja) | 2018-06-04 | 2019-06-04 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
| JP2023189072A Active JP7827673B2 (ja) | 2018-06-04 | 2023-11-06 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
| JP2025184908A Withdrawn JP2026031977A (ja) | 2018-06-04 | 2025-10-31 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567215A Pending JP2021525534A (ja) | 2018-06-04 | 2019-06-04 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025184908A Withdrawn JP2026031977A (ja) | 2018-06-04 | 2025-10-31 | Muc16特異的キメラ抗原受容体およびそれらの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US11319380B2 (enExample) |
| EP (1) | EP3802615A4 (enExample) |
| JP (3) | JP2021525534A (enExample) |
| KR (1) | KR102974340B1 (enExample) |
| CN (2) | CN112533957B (enExample) |
| AU (1) | AU2019282620B2 (enExample) |
| CA (1) | CA3101641A1 (enExample) |
| IL (1) | IL278976A (enExample) |
| SG (1) | SG11202011895VA (enExample) |
| WO (1) | WO2019236577A2 (enExample) |
| ZA (3) | ZA202008065B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| KR102742741B1 (ko) * | 2017-10-18 | 2024-12-16 | 프레시전 인코포레이티드 | 스페이서를 포함하는 폴리펩타이드 조성물 |
| EP4578507A3 (en) * | 2018-11-01 | 2025-11-12 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Compositions and methods for t cell engineering |
| CN114651003A (zh) | 2019-09-10 | 2022-06-21 | 黑曜石疗法公司 | 用于可调调节的ca2-il15融合蛋白 |
| CN115885038A (zh) * | 2020-06-17 | 2023-03-31 | 国立大学法人京都大学 | 表达嵌合抗原受体的免疫活性细胞 |
| JP2024500189A (ja) * | 2020-12-21 | 2024-01-04 | アロジーン セラピューティクス,インコーポレイテッド | プロテアーゼ活性化cd45ゲートcar |
| TW202233662A (zh) * | 2020-12-31 | 2022-09-01 | 大陸商亘喜生物科技(上海)有限公司 | 膜融合蛋白及其在免疫細胞中的應用 |
| JP7893814B2 (ja) * | 2021-01-19 | 2026-07-22 | オブシディアン セラピューティクス, インコーポレイテッド | T細胞及び腫瘍浸潤リンパ球の拡張のための組成物及び方法 |
| JP2024507958A (ja) * | 2021-02-26 | 2024-02-21 | ナンジン レジェンド バイオテック カンパニー,リミテッド | 外因的に導入されたサイトカインを発現する操作された免疫エフェクター細胞 |
| WO2023150562A1 (en) * | 2022-02-01 | 2023-08-10 | Alaunos Therapeutics, Inc. | Methods for activation and expansion of t cells |
| CN115819613B (zh) * | 2022-05-10 | 2023-10-20 | 四川大学华西医院 | 基于msln前体蛋白构建的嵌合抗原受体免疫细胞制备及其应用 |
| CN116196402A (zh) * | 2022-11-01 | 2023-06-02 | 山东大学齐鲁医院 | 表达双特异性抗体的溶瘤腺病毒联合cart在肿瘤治疗中的应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006502110A (ja) | 2002-07-03 | 2006-01-19 | イミュノジェン・インコーポレーテッド | 非放出Muc1およびMuc16に対する抗体、およびその使用 |
| US7989595B2 (en) | 2005-06-20 | 2011-08-02 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| PE20090245A1 (es) | 2007-05-08 | 2009-03-17 | Genentech Inc | Anticuerpos anti-muc16 disenados con cisteina y conjugados de anticuerpos y farmacos |
| EP2388323B1 (en) | 2008-01-11 | 2016-04-13 | Gene Techno Science Co., Ltd. | Humanized anti-9 integrin antibodies and the uses thereof |
| JP5956342B2 (ja) * | 2009-11-03 | 2016-07-27 | シティ・オブ・ホープCity of Hope | 形質導入T細胞選択のためのトランケート上皮増殖因子レセプタ(EGFRt) |
| CA2793753C (en) * | 2010-03-26 | 2018-06-05 | Memorial Sloan-Kettering Cancer Center | Antibodies to muc16 and methods of use thereof |
| EP3789487A1 (en) | 2013-04-03 | 2021-03-10 | Memorial Sloan Kettering Cancer Center | Effective generation of tumor-targeted t-cells derived from pluripotent stem cells |
| EP2997134B1 (en) * | 2013-05-14 | 2020-06-24 | Board of Regents, The University of Texas System | Human application of engineered chimeric antigen receptor (car) t-cells |
| ES2765710T3 (es) * | 2014-04-03 | 2020-06-10 | Cellectis | Receptores de antígeno quimérico específicos de CD33 para la inmunoterapia del cáncer |
| AU2015292744C1 (en) * | 2014-07-21 | 2021-01-21 | Novartis Ag | Treatment of cancer using humanized anti-BCMA chimeric antigen receptor |
| EP3273994B1 (en) | 2015-03-27 | 2021-12-01 | University of Southern California | Car t-cell therapy directed to lhr for the treatment of solid tumors |
| US10017577B2 (en) | 2015-06-15 | 2018-07-10 | Genentech, Inc. | Antibodies and immunoconjugates |
| US11242375B2 (en) | 2015-09-04 | 2022-02-08 | Memorial Sloan Kettering Cancer Center | Immune cell compositions and methods of use |
| US20190112380A1 (en) * | 2016-03-29 | 2019-04-18 | University Of Southern California | Chimeric antigen receptors targeting cancer |
| CN118652336A (zh) * | 2016-06-08 | 2024-09-17 | 普瑞赛格恩公司 | Cd33特异性嵌合抗原受体 |
| JP2019524706A (ja) * | 2016-07-08 | 2019-09-05 | ジェネンテック, インコーポレイテッド | Muc16陽性癌治療の応答性を評価するためのヒト精巣上体タンパク質4(he4)の使用 |
| JP7295795B2 (ja) | 2016-07-29 | 2023-06-21 | ジュノー セラピューティクス インコーポレイテッド | 免疫調節ポリペプチドならびに関連する組成物および方法 |
| JP7050770B2 (ja) * | 2016-10-05 | 2022-04-08 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | 抗体薬物コンジュゲートの調製方法 |
| CN107557336B (zh) * | 2017-09-15 | 2020-02-14 | 山东兴瑞生物科技有限公司 | 一种抗muc16安全型嵌合抗原受体修饰的免疫细胞及其应用 |
-
2019
- 2019-06-04 CN CN201980052129.8A patent/CN112533957B/zh active Active
- 2019-06-04 US US16/431,193 patent/US11319380B2/en active Active
- 2019-06-04 SG SG11202011895VA patent/SG11202011895VA/en unknown
- 2019-06-04 JP JP2020567215A patent/JP2021525534A/ja active Pending
- 2019-06-04 WO PCT/US2019/035384 patent/WO2019236577A2/en not_active Ceased
- 2019-06-04 AU AU2019282620A patent/AU2019282620B2/en active Active
- 2019-06-04 CA CA3101641A patent/CA3101641A1/en active Pending
- 2019-06-04 EP EP19815389.2A patent/EP3802615A4/en active Pending
- 2019-06-04 KR KR1020207038033A patent/KR102974340B1/ko active Active
- 2019-06-04 CN CN202610008767.1A patent/CN121852427A/zh active Pending
-
2020
- 2020-11-25 IL IL278976A patent/IL278976A/en unknown
- 2020-12-23 ZA ZA2020/08065A patent/ZA202008065B/en unknown
-
2021
- 2021-12-22 ZA ZA2021/10780A patent/ZA202110780B/en unknown
-
2022
- 2022-02-04 US US17/650,018 patent/US11981746B2/en active Active
- 2022-02-04 US US17/650,025 patent/US11976134B2/en active Active
-
2023
- 2023-11-06 JP JP2023189072A patent/JP7827673B2/ja active Active
- 2023-12-19 ZA ZA2023/11718A patent/ZA202311718B/en unknown
-
2024
- 2024-04-05 US US18/628,575 patent/US20240368305A1/en active Pending
-
2025
- 2025-10-31 JP JP2025184908A patent/JP2026031977A/ja not_active Withdrawn
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