JP2024015491A5 - - Google Patents
Info
- Publication number
- JP2024015491A5 JP2024015491A5 JP2023200811A JP2023200811A JP2024015491A5 JP 2024015491 A5 JP2024015491 A5 JP 2024015491A5 JP 2023200811 A JP2023200811 A JP 2023200811A JP 2023200811 A JP2023200811 A JP 2023200811A JP 2024015491 A5 JP2024015491 A5 JP 2024015491A5
- Authority
- JP
- Japan
- Prior art keywords
- antisense oligonucleotide
- length
- toehold
- complementary strand
- antisense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021198890 | 2021-12-07 | ||
| JP2021198890 | 2021-12-07 | ||
| JP2023510304A JP7412668B2 (ja) | 2021-12-07 | 2022-09-30 | アンチセンスオリゴヌクレオチド複合体 |
| PCT/JP2022/036699 WO2023105898A1 (ja) | 2021-12-07 | 2022-09-30 | アンチセンスオリゴヌクレオチド複合体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023510304A Division JP7412668B2 (ja) | 2021-12-07 | 2022-09-30 | アンチセンスオリゴヌクレオチド複合体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024015491A JP2024015491A (ja) | 2024-02-02 |
| JP2024015491A5 true JP2024015491A5 (enExample) | 2025-10-03 |
Family
ID=86730115
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023510304A Active JP7412668B2 (ja) | 2021-12-07 | 2022-09-30 | アンチセンスオリゴヌクレオチド複合体 |
| JP2023200811A Pending JP2024015491A (ja) | 2021-12-07 | 2023-11-28 | アンチセンスオリゴヌクレオチド複合体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023510304A Active JP7412668B2 (ja) | 2021-12-07 | 2022-09-30 | アンチセンスオリゴヌクレオチド複合体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250297249A1 (enExample) |
| EP (1) | EP4446414A4 (enExample) |
| JP (2) | JP7412668B2 (enExample) |
| CN (1) | CN118660965A (enExample) |
| WO (1) | WO2023105898A1 (enExample) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013089283A1 (en) * | 2011-12-16 | 2013-06-20 | National University Corporation Tokyo Medical And Dental University | Chimeric double-stranded nucleic acid |
| AU2014272526A1 (en) * | 2013-05-30 | 2015-12-10 | National University Corporation Tokyo Medical And Dental University | Double-stranded agents for delivering therapeutic oligonucleotides |
| CA2915443A1 (en) * | 2013-06-16 | 2014-12-24 | National University Corporation Tokyo Medical And Dental University | Double-stranded antisense nucleic acid with exon-skipping effect |
| WO2016161388A1 (en) * | 2015-04-03 | 2016-10-06 | University Of Massachusetts | Fully stabilized asymmetric sirna |
| EP3571300A1 (en) * | 2017-01-19 | 2019-11-27 | ProQR Therapeutics II B.V. | Oligonucleotide complexes for use in rna editing |
| CN110799647A (zh) * | 2017-06-23 | 2020-02-14 | 马萨诸塞大学 | 双尾自递送sirna及相关的方法 |
| JP7333079B2 (ja) * | 2018-03-19 | 2023-08-24 | 国立大学法人 東京医科歯科大学 | 毒性が軽減した核酸 |
-
2022
- 2022-09-30 JP JP2023510304A patent/JP7412668B2/ja active Active
- 2022-09-30 WO PCT/JP2022/036699 patent/WO2023105898A1/ja not_active Ceased
- 2022-09-30 EP EP22903832.8A patent/EP4446414A4/en active Pending
- 2022-09-30 CN CN202280081447.9A patent/CN118660965A/zh active Pending
- 2022-09-30 US US18/717,295 patent/US20250297249A1/en active Pending
-
2023
- 2023-11-28 JP JP2023200811A patent/JP2024015491A/ja active Pending
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